| (R)-(-)-1-METHYL-3-PYRROLIDINOL | ||
|
PRODUCT IDENTIFICATION |
||
| CAS NO. | 104641-60-3 |
|
| EINECS NO. | ||
| FORMULA | C5H11NO | |
| MOL WT. | 101.15 | |
|
H.S. CODE |
||
| DERIVATION |
|
|
| SYNONYMS | (R)-3-Hydroxy-N-methylpyrrolidine; (R)-MPD; | |
|
TOXICITY |
|
|
|
CLASSIFICATION |
||
|
PHYSICAL AND CHEMICAL PROPERTIES |
||
| PHYSICAL STATE |
yellowish liquid |
|
| MELTING POINT | ||
| BOILING POINT | 50 - 52 C at 1 mm Hg | |
| SPECIFIC GRAVITY | 0.921 | |
| SOLUBILITY IN WATER | ||
| pH | ||
| VAPOR DENSITY |
|
|
|
AUTOIGNITION |
||
|
NFPA RATINGS |
||
|
REFRACTIVE INDEX |
1.4640 | |
| FLASH POINT |
|
|
| STABILITY |
Stable under ordinary conditions. |
|
|
GENERAL DESCRIPTION |
||
| Pyrrolidine is a part of the structure of amino acids (proline, hydroxyproline and hygrine). Chiral pyrrolidines are used as enantiomeric intermediate for the asysmmetric single isomeric drugs including antitumor, anesthetic, antipasmodic, hepatotoxic, antiinflammatory or anti-HIV activity products. They are useful in preparing pyridone carboxylic acid antibacterials, k-receptor opioids, and optically secondary alcohols. | ||
| SALES SPECIFICATION | ||
|
APPEARANCE |
yellowish liquid |
|
|
CHEMICAL PURITY |
99.0% min | |
|
OPTICAL PURITY |
99.0% min | |
|
OPTICAL ROTATION |
-6° ~ -8° (C=1 in Chloroform) | |
| TRANSPORTATION | ||
| PACKING |
|
|
| HAZARD CLASS | Not regulated | |
| UN NO. | ||
| OTHER INFORMATION | ||
| Hazard Symbols: XI, Risk Phrases: 36/37/38, Safety Phrases: 26-37/39 | ||
| GENERAL DESCRIPTION OF PYROLLE | ||
| Pyrrole: One of a class of organic heterocyclic compounds of five-membered diunsaturated ring structure composed of four carbon atoms and one nitrogen atom. The simplest member of the pyrrole family is pyrrole itself, a basic heterocyclic compound; colorless to pale yellow, toxic oil with pungent taste and similar to chloroform odor; insoluble in water; soluble in alcohol, ether, and dilute acids; boils at 129 - 131 C; polymerizes in light. Pyrrole ring system is involved in coloured products (green pigment, chlorophyll; red, hemoglobin; , blue, indigo) in nature. Pyrrolidine, the saturated tetrahydropyrrole, is part of the structures of amino acids (proline, hydroxyproline and hygrine). Pyrroline is a pyrrole in which one of the two solid bonds has been hydrogenated. Pyrrole and its derivatives are widely used as an intermediate in synthesis of pharmaceuticals, medicines, agrochemicals, dyes, photographic chemicals, perfumes and other organic compounds. They are also used as catalysts for polymerization process, corrosion inhibitors, preservatives, and as solvents for resins and terpenes. They are used in metallurgical processes. They are useful in the intensive study of transition-metal complex catalyst chemistry for uniform polymerization, luminescence chemistry and spectrophotometric analysis. | ||
