D-ALANINOL

PRODUCT IDENTIFICATION
CAS NO. 35320-23-1

D-ALANINOL
EINECS NO.

 
FORMULA CH3CH(NH2)CH2OH
MOL WT. 75.11

H.S. CODE

  

TOXICITY

 
SYNONYMS (R)-1-Amino-2-propanol; (R)-1-Aminopropan-2-ol;
(R)-(-)-2-Amino-1-propanol;

DERIVATION

 

CLASSIFICATION

  

PHYSICAL AND CHEMICAL PROPERTIES
PHYSICAL STATE

clear to yellowish oily liquid
MELTING POINT  
BOILING POINT 166 - 168 C
SPECIFIC GRAVITY 0.965
SOLUBILITY IN WATER  
pH  
VAPOR DENSITY

 

AUTOIGNITION

  

NFPA RATINGS

  

REFRACTIVE INDEX

 1.4490 - 1.4510
FLASH POINT

84 C
STABILITY

Stable under ordinary conditions. Hygroscopic.

GENERAL DESCRIPTION

Chiral amino alcohols and their N-protected derivatives (Cbz, t-Boc, and Fmoc) are versatile building blocks, auxiliaries, ligand or resolving agent in asymmetric synthesis for biological research and pharmaceutical applications such as antitumor, anesthetic, antipasmodic, hepatotoxic, antiinflammatory or anti-HIV activities. They are used in the synthesis of beta-blockers, HIV protease and ACE inhibitors, chiral auxiliaries and catalytic enantioselective ligands. Their derivatives include the forms of;
  • C-terminal peptibiols
  • Amphiphylic antibacterial peptides
  • Oligocarbamates
  • Analogs of peptides
  • Aziridines, Halogen aminoalkyls
  • Enantiomerical alpha-alkyl mono and diamines
  • Enantiomerical beta-substituted amines
  • Enantiomerical beta-amino acids beta-amino sulfoxides, beta-amino sulfides and beta-amino thiols.
  • The precursors of diverse compounds such as statines, sphingolipides and peptide isosteres.
SALES SPECIFICATION

APPEARANCE

clear to yellowish oily liquid

CHEMICAL PURITY

 98.5% min (G.C)
ENANTIOMERIC EXCESS 99.0% min (G.C)
TRANSPORTATION
PACKING
 
HAZARD CLASS 8 (Packing Group: II)
UN NO. 2735
OTHER INFORMATION
Hazard Symbols: C, Risk Phrases: 34, Safety Phrases: 26-36/37/39-45
Optical Rotation: -20° ~ -24° (C=2 in EtOH)