D-METHIONINOL

PRODUCT IDENTIFICATION

CAS NO. 87206-44-8

D-METHIONINOL

EINECS NO.  
FORMULA C5H13NOS
MOL WT. 135.22

H.S. CODE

 

TOXICITY

 

SYNONYMS D-2-Amino-4-methylthiobutan-1-ol;
D-2-Amino-4-metiltiobutan-1-ol; D-2-Amino-4-méthylthiobutane-1-ol; (R)-(+)-2-amino-4-methylthio-1-butanol;

DERIVATION

 

CLASSIFICATION

 

PHYSICAL AND CHEMICAL PROPERTIES

PHYSICAL STATE

clear crystals

MELTING POINT 31 - 33 C
BOILING POINT 198 - 200 C
SPECIFIC GRAVITY 1.09 - 1.10
SOLUBILITY IN WATER  
pH  
VAPOR DENSITY

 

AUTOIGNITION

 

NFPA RATINGS

 

REFRACTIVE INDEX

1.4511
FLASH POINT

90 C

STABILITY

Stable under ordinary conditions. Hygroscopic.

GENERAL DESCRIPTION

METHIONINE, an essential amino acid (sulfur-containing) that is not synthesized by the body and must be obtained from food. It contributes to supply mineral sulfur improving the tone and pliability of the skin, conditioning the hair and strengthens nails and protecting the cells from airborne pollutants. It contributes to the other compounds including S-adenosyl-methionine (SAM), which participate in liabile methyl groups and sulfur to over 100 biochemical reactions for normal brain function, and L-Cysteine, which is a component of Glutathione, an important antioxidant molecule in the body.  Methionine is also a transporter of the antioxidant mineral Selenium. METHIONINE occurs as two optical isomers, a dextro and a levo form.

Chiral amino alcohol possessing both amine and alcohol is a structural motif for the compounds which have important biological and pharmacological functions within the body as inhibitor of aspartyl proteases, aldose reductase, b-amyloid peptide formation, and dopamine D4 antagonists. The chiral amino alcohol also exhibits anti-inflammatory, anesthetic, antipasmodic, hepatotoxic, anti-diabetic, anti-obesity,and anti-depressant activities. Chiral amino alcohols and their N-protected derivatives (Cbz, t-Boc, and Fmoc) are versatile building blocks, auxiliaries, ligand or resolving agent in asymmetric synthesis for biological and pharmaceutical researches. applications are present in the field of antitumor, anesthetic, antipasmodic, hepatotoxic, antiinflammatory or anti-HIV activities.  Their derivatives include the forms of;

  • C-terminal peptibiols
  • Amphiphylic antibacterial peptides
  • Oligocarbamates
  • Analogs of peptides
  • Aziridines, Halogen aminoalkyls
  • Enantiomerical alpha-alkyl mono and diamines
  • Enantiomerical beta-substituted amines
  • Enantiomerical beta-amino acids beta-amino sulfoxides, beta-amino sulfides and
  • beta-amino thiols.
  • The precursors of diverse compounds such as statines, sphingolipides and peptide isosteres.
SALES SPECIFICATION

APPEARANCE

clear crystals

CHEMICAL PURITY

97.5% min

OPTICAL PURITY

97.5% min
OPTICAL ROTATION +11.5° ~ +12.5° (C=neat)
TRANSPORTATION
PACKING
 
HAZARD CLASS  
UN NO.  
OTHER INFORMATION
Hazard Symbols: XI, Risk Phrases: 36/37/38, Safety Phrases: 22-24/26