D-TYROSINOL HYDROCHLORIDE

PRODUCT IDENTIFICATION

CAS NO. 40829-04-7

L-TYROSINOL HYDROCHLORIDE

EINECS NO.  
FORMULA C9H13NO2·HCl
MOL WT. 203.67

H.S. CODE

 

TOXICITY

 

SYNONYMS [(R)-3-(4-Hydroxyphenyl)-2-amino-1-propanol] Hydrochloride;
(R)-beta-Amino-4-hydroxybenzenepropanol hydrochloride;

DERIVATION

 

CLASSIFICATION

 

PHYSICAL AND CHEMICAL PROPERTIES

PHYSICAL STATE

white crystalline powder

MELTING POINT 161 - 165 C (Decomposes)
BOILING POINT  
SPECIFIC GRAVITY  
SOLUBILITY IN WATER Soluble
pH  
VAPOR DENSITY

 

AUTOIGNITION

 

NFPA RATINGS

 

REFRACTIVE INDEX

 
FLASH POINT

 

STABILITY

Stable under ordinary conditions.

GENERAL DESCRIPTION

Chiral amino alcohols and their N-protected derivatives (Cbz, t-Boc, and Fmoc) are versatile building blocks, auxiliaries, ligand or resolving agent in asymmetric synthesis for biological research and pharmaceutical applications such as antitumor, anesthetic, antipasmodic, hepatotoxic, antiinflammatory or anti-HIV activities. They are used in the synthesis of beta-blockers, HIV protease and ACE inhibitors, chiral auxiliaries and catalytic enantioselective ligands. Their derivatives include the forms of;
  • C-terminal peptibiols
  • Amphiphylic antibacterial peptides
  • Oligocarbamates
  • Analogs of peptides
  • Aziridines, Halogen aminoalkyls
  • Enantiomerical alpha-alkyl mono and diamines
  • Enantiomerical beta-substituted amines
  • Enantiomerical beta-amino acids beta-amino sulfoxides, beta-amino sulfides and beta-amino thiols.
  • The precursors of diverse compounds such as statines, sphingolipides and peptide isosteres.
(R,R)-(-)-2,4-Pentanediol is an effective diol for asymmetric chiral applications such as chiral auxiliaries, building blocks, chiral ligands.
SALES SPECIFICATION

APPEARANCE

white crystalline powder

CHEMICAL PURITY

98.5% min (G.C)
ENANTIOMERIC EXCESS 99.0% min (G.C)
TRANSPORTATION
PACKING
 
HAZARD CLASS 8 (Packing Group: II)
UN NO. 2735
OTHER INFORMATION
Hazard Symbols: XI, Risk Phrases: 3637/38, Safety Phrases: 26-37/39
Optical Rotation: +17° ~ +19° (C=1 in water)