L-ALANINOL

PRODUCT IDENTIFICATION
CAS NO. 2749-11-3

L-ALANINOL
EINECS NO. 220-388-7
FORMULA CH3CH(NH2)CH2OH
MOL WT. 75.11

H.S. CODE

  

TOXICITY

 
SYNONYMS 2-Amino-1-propanol; (S)-(+)-2-Amino-1-propanol;

DERIVATION

 

CLASSIFICATION

  

PHYSICAL AND CHEMICAL PROPERTIES
PHYSICAL STATE

clear to pale yellow liquid
MELTING POINT  
BOILING POINT 166 - 168 C
SPECIFIC GRAVITY 0.960 - 0.965
SOLUBILITY IN WATER  
pH  
VAPOR DENSITY

 

AUTOIGNITION

  

NFPA RATINGS

  

REFRACTIVE INDEX

 1.4480 - 1.451
FLASH POINT

62 C
STABILITY

Stable under ordinary conditions. Hygroscopic.

GENERAL DESCRIPTION

Chiral amino alcohols and their N-protected derivatives (Cbz, t-Boc, and Fmoc) are versatile building blocks, auxiliaries, ligand or resolving agent in asymmetric synthesis for biological research and pharmaceutical applications such as antitumor, anesthetic, antipasmodic, hepatotoxic, antiinflammatory or anti-HIV activities. They are used in the synthesis of beta-blockers, HIV protease and ACE inhibitors, chiral auxiliaries and catalytic enantioselective ligands. Their derivatives include the forms of;
  • C-terminal peptibiols
  • Amphiphylic antibacterial peptides
  • Oligocarbamates
  • Analogs of peptides
  • Aziridines, Halogen aminoalkyls
  • Enantiomerical alpha-alkyl mono and diamines
  • Enantiomerical beta-substituted amines
  • Enantiomerical beta-amino acids beta-amino sulfoxides, beta-amino sulfides and beta-amino thiols.
  • The precursors of diverse compounds such as statines, sphingolipides and peptide isosteres.

An example of end product from L-alaninol is "levofloxacin" , a quinolone class antibiotic.
SALES SPECIFICATION

APPEARANCE

clear to pale yellow liquid

IDENTIFICATION

pass IR

CHEMICAL PURITY

 97.5% min

OPTICAL PURITY

 97.5% min

WATER

 1.0% max
TRANSPORTATION
PACKING
 
HAZARD CLASS 8 (Packing Group: II)
UN NO. 2735
OTHER INFORMATION
Hazard Symbols: C, Risk Phrases: 34, Safety Phrases: 26-36/37/39-45
Optical Rotation: +20° ~ +24° (C=2 in EtOH))