L-METHIONINOL |
PRODUCT
IDENTIFICATION
|
CAS
NO. |
2899-37-8 |
|
EINECS
NO. |
220-788-1 |
FORMULA |
C5H13NOS |
MOL
WT. |
135.22 |
H.S.
CODE
|
|
TOXICITY
|
|
SYNONYMS |
L-2-Amino-4-methylthiobutan-1-ol;
|
L-2-Amino-4-metiltiobutan-1-ol;
L-2-Amino-4-méthylthiobutane-1-ol; (S)-(-)-2-amino-4-methylthio-1-butanol;
|
DERIVATION
|
|
CLASSIFICATION
|
|
PHYSICAL
AND CHEMICAL PROPERTIES
|
PHYSICAL
STATE |
clear
crystals
|
MELTING
POINT |
31
- 33 C |
BOILING
POINT |
198 - 200 C |
SPECIFIC
GRAVITY |
1.09
- 1.10 |
SOLUBILITY
IN WATER |
|
pH |
|
VAPOR
DENSITY |
|
AUTOIGNITION
|
|
NFPA
RATINGS
|
|
REFRACTIVE
INDEX
|
1.4511 |
FLASH
POINT |
90
C
|
STABILITY |
Stable
under ordinary conditions. Hygroscopic. |
GENERAL
DESCRIPTION
|
Chiral amino
alcohols and their N-protected derivatives (Cbz, t-Boc, and Fmoc)
are versatile building blocks, auxiliaries, ligand
or resolving agent in asymmetric synthesis for biological research and
pharmaceutical applications such as antitumor, anesthetic, antipasmodic,
hepatotoxic, antiinflammatory or anti-HIV activities. They are used in the
synthesis of beta-blockers, HIV protease and ACE inhibitors, chiral auxiliaries
and catalytic enantioselective ligands. Their derivatives include the forms
of;
- C-terminal
peptibiols
- Amphiphylic
antibacterial peptides
- Oligocarbamates
- Analogs of
peptides
- Aziridines,
Halogen aminoalkyls
- Enantiomerical alpha-alkyl mono and
diamines
- Enantiomerical beta-substituted amines
- Enantiomerical beta-amino acids beta-amino
sulfoxides, beta-amino sulfides and beta-amino thiols.
- The
precursors of diverse compounds such as statines, sphingolipides and peptide
isosteres.
|
SALES
SPECIFICATION |
APPEARANCE
|
clear
crystals
|
CHEMICAL
PURITY
|
97.5%
min |
OPTICAL
PURITY
|
97.5%
min |
OPTICAL
ROTATION |
-20° ~ -22° (C=5 in Water)) |
TRANSPORTATION |
PACKING |
|
HAZARD
CLASS |
|
UN
NO. |
|
OTHER
INFORMATION |
Hazard Symbols: XI, Risk Phrases: 36/37/38,
Safety Phrases: 22-24/26 |
|