Fmoc-AEEA

Synonyms. Fmoc-8-amino-3,6-dioxaoctanoic acid; Fmoc-NH-PEG2-CH2COOH; (2-(2-(Fmoc-amino)ethoxy)ethoxy)acetic acid; 8-(Fmoc-amino)-3,6-dioxaoctanoic acid; Fmoc-AEEAc-OH;

Fmoc-AEEA

 

PRODUCT IDENTIFICATION

CAS RN

166108-71-0

EINECS RN

 

FORMULA

C21H23NO6

MOLE WEIGHT

385.41

H.S CODE

2924.29.7100

SMILES

C2(C1=C(C=CC=C1)C3=C2C=CC=C3)COC(=O)NCCOCCOCC(=O)O

CLASSIFICATION

PEGylation

EXTRA NOTES

PEG Based Spacer

 

PHYSICAL AND CHEMICAL PROPERTIES

PHYSICAL STATE.

white crystals

MELTING POINT

 

BOILING POINT

631 C

DENSITY

1.265

SOLUBILITY IN WATER

 

SOLVENT SOLUBILITY  

VAPOR DENSITY

 

log P(octanol-water)

 

VAPOR PRESSURE

 

AUTOIGNITION TEMP

 
pH

 

REFRACTIVE INDEX

 

FLASH POINT

335 C

 

STABILITY AND REACTIVITY
STABILITY Stable under normal conditions.

INCOMPATIBLE MATERIALS

Strong oxidizing agents

POLYMERIZATION

Has not been reported

NFPA RATINGS

 

 

EXTERNAL LINKS & GENERAL DESCRIPTION

Wikipedia Linking - PEGylation

Google Scholar Search

PubChem Compound Summary - Fmoc-AEEA

http://www.ncbi.nlm.nih.gov/ - PEGylation 

http://www.sigmaaldrich.com/
PEG polymers contain numerous inherent favorable biological characteristics including high water solubility and a lack of toxicity and immunogenicity. Thus, the chemical modification of biologically active compounds, such as peptides, antibody fragments, enzymes, or small molecules with polyethylene glycol chains, referred to as “PEGylation”, often leads to improved pharmacokinetics and biological function in many applications.

Local:

PEGylation reagent

CAS RN

Cbz-AEEA 16545-06-8

Fmoc-AEEA

166108-71-0

Fmoc-AEA

260367-12-2

Fmoc-NH-(PEG)4-CH2CH2COOH557756-85-1
Boc-NH-(PEG)2-CH2CH2COOH·DCHA560088-79-1
Boc-PEG-acid (n=7)600141-83-1
Boc-NH-(PEG)4-CH2CH2COOH756525-91-4
Cbz-NH-(PEG)5-CH2CH2COOH  756526-00-8 
Fmoc-NH-(PEG)12-CH2CH2COOH756526-01-9

Fmoc-NH-(PEG)8-CH2CH2COOH

756526-02-0

Azido-PEG-acid (n=8)

846549-37-9

Fmoc-NH-(PEG)3-CH2CH2COOH867062-95-1
Fmoc-DOOA·HCl

868599-73-9

Fmoc-TOTA·HCl

868599-75-1

Fmoc-AEEP

872679-70-4

Methoxytrityl-S-(PEG)4-acid882847-05-4
Boc-NH-(PEG)6-CH2CH2COOH882847-13-4
Fmoc-NH-(PEG)5-CH2CH2COOH882847-32-7
Fmoc-NH-(PEG)6-CH2CH2COOH882847-34-9
Fmoc-NH-(PEG)3-CH2CH2COOH916585-44-9
Trt-NH-(PEG)2-NH2927888-44-6
Fmoc-NH-(PEG)9-CH2CH2COOH 1191064-81-9

 

SALES SPECIFICATION

APPEARANCE

white crystals

PURITY

98.0% min

 

TRANSPORT & REGULATORY INFORMATION

UN NO.

Not regulated

HAZARD SYMBOL

 
PACKING GROUP  

 

SAFETY INFORMATION

HAZARD OVERVIEW

Not known

GHS

 

SIGNAL WORD

 

PICTOGRAMS

 

HAZARD STATEMENTS

 

P STATEMENTS

 

EC DIRECTIVES

 

HAZARD CODES

 

RISK PHRASES

 

SAFETY PHRASES

22-24/25

 

PACKING

 

 

PRICE INFORMATION