Fmoc-AEEA
Synonyms. Fmoc-8-amino-3,6-dioxaoctanoic acid; Fmoc-NH-PEG2-CH2COOH; (2-(2-(Fmoc-amino)ethoxy)ethoxy)acetic acid; 8-(Fmoc-amino)-3,6-dioxaoctanoic acid; Fmoc-AEEAc-OH;

Fmoc-AEEA
 

PRODUCT IDENTIFICATION

CAS RN

 166108-71-0

EINECS RN

  

FORMULA

 C21H23NO6

MOLE WEIGHT

 385.41

H.S CODE

 2924.29.7100

SMILES

 C2(C1=C(C=CC=C1)C3=C2C=CC=C3)COC(=O)NCCOCCOCC(=O)O

CLASSIFICATION

PEGylation

EXTRA NOTES

PEG Based Spacer

 

PHYSICAL AND CHEMICAL PROPERTIES

PHYSICAL STATE.

white crystals

MELTING POINT

 

BOILING POINT

 631 C

DENSITY

1.265

SOLUBILITY IN WATER

 
SOLVENT SOLUBILITY  

VAPOR DENSITY

 

log P(octanol-water)

  

VAPOR PRESSURE

  

AUTOIGNITION TEMP

  
pH

 

REFRACTIVE INDEX

 

FLASH POINT

335 C

 
STABILITY AND REACTIVITY
STABILITY Stable under normal conditions.

INCOMPATIBLE MATERIALS

Strong oxidizing agents
POLYMERIZATION

Has not been reported

NFPA RATINGS

 

 

EXTERNAL LINKS & GENERAL DESCRIPTION

Wikipedia Linking - PEGylation

Google Scholar Search

PubChem Compound Summary - Fmoc-AEEA

http://www.ncbi.nlm.nih.gov/ - PEGylation 

http://www.sigmaaldrich.com/
PEG polymers contain numerous inherent favorable biological characteristics including high water solubility and a lack of toxicity and immunogenicity. Thus, the chemical modification of biologically active compounds, such as peptides, antibody fragments, enzymes, or small molecules with polyethylene glycol chains, referred to as “PEGylation”, often leads to improved pharmacokinetics and biological function in many applications.

Local:

PEGylation reagent

CAS RN
Cbz-AEEA 16545-06-8

Fmoc-AEEA

166108-71-0

Fmoc-AEA

260367-12-2
Fmoc-NH-(PEG)4-CH2CH2COOH557756-85-1
Boc-NH-(PEG)2-CH2CH2COOH·DCHA560088-79-1
Boc-PEG-acid (n=7)600141-83-1
Boc-NH-(PEG)4-CH2CH2COOH756525-91-4
Cbz-NH-(PEG)5-CH2CH2COOH  756526-00-8 
Fmoc-NH-(PEG)12-CH2CH2COOH756526-01-9

Fmoc-NH-(PEG)8-CH2CH2COOH

756526-02-0
Azido-PEG-acid (n=8)

846549-37-9

Fmoc-NH-(PEG)3-CH2CH2COOH867062-95-1
Fmoc-DOOA·HCl

868599-73-9

Fmoc-TOTA·HCl

868599-75-1

Fmoc-AEEP

872679-70-4
Methoxytrityl-S-(PEG)4-acid882847-05-4
Boc-NH-(PEG)6-CH2CH2COOH882847-13-4
Fmoc-NH-(PEG)5-CH2CH2COOH882847-32-7
Fmoc-NH-(PEG)6-CH2CH2COOH882847-34-9
Fmoc-NH-(PEG)3-CH2CH2COOH916585-44-9
Trt-NH-(PEG)2-NH2927888-44-6
Fmoc-NH-(PEG)9-CH2CH2COOH 1191064-81-9

 

SALES SPECIFICATION

APPEARANCE

white crystals

PURITY

98.0% min

 

TRANSPORT & REGULATORY INFORMATION

UN NO.

Not regulated

HAZARD SYMBOL

  
PACKING GROUP  

 

SAFETY INFORMATION

HAZARD OVERVIEW

Not known

GHS

  

SIGNAL WORD

 

PICTOGRAMS

 

HAZARD STATEMENTS

 

P STATEMENTS

 
EC DIRECTIVES

 
HAZARD CODES

 

RISK PHRASES

  

SAFETY PHRASES

 22-24/25

 

PACKING

 

 

PRICE INFORMATION