4-NITROBENZYL CHLOROFORMATE

Synonyms. 4-Nitrocarbobenzoxychloride; Carbonochloridic acid (4-nitrophenyl)methyl ester; 4-Nitrobenzyl chloroformate;

4-NITROBENZYL CHLOROFORMATE

 

PRODUCT IDENTIFICATION

CAS RN

4457-32-3

EINECS RN

224-708-6

FORMULA

ClCO2C6H4NO2

MOLE WEIGHT

215.59

H.S CODE

2915.90.2000

SMILES

O=C(OCc1ccc([N+](=O)[O-])cc1)Cl

CLASSIFICATION

 

EXTRA NOTES

Protection of amines, alcohols in peptide synthesis

 

PHYSICAL AND CHEMICAL PROPERTIES

PHYSICAL STATE.

brown semi-solid

MELTING POINT

32 - 34 C

BOILING POINT

 

DENSITY

 

SOLUBILITY IN WATER

 

SOLVENT SOLUBILITY  

VAPOR DENSITY

 

log P(octanol-water)

 

VAPOR PRESSURE

 

AUTOIGNITION TEMP

 
pH

 

REFRACTIVE INDEX

 

FLASH POINT

113 C

 

STABILITY AND REACTIVITY
STABILITY Stable under normal conditions.

INCOMPATIBLE MATERIALS

Strong oxidizing agents, strong acids

POLYMERIZATION

Has not been reported

NFPA RATINGS

Health: 3; Flammability: 1; Reactivity: 0

 

EXTERNAL LINKS & GENERAL DESCRIPTION

Wikipedia Linking - Chloroformic acid

Google Scholar Search

PubChem Compound Summary - 4-Nitrobenzyl chloroformate

http://www.ncbi.nlm.nih.gov/ - 4-Nitrobenzyl chloroformate

http://journal.kcsnet.or.kr/
Nucleophilic Substitution Reactions of p-Nitrobenzyl Chloroformate

Local:
N-protecting agent for peptidomimetics and biological research. It is used in manufacturing antibacterial agents (imipenem, panipenem, meropenem)

 

SALES SPECIFICATION

APPEARANCE

brown semi-solid

IDENTITY

pass (IR)

PURITY 

98.5% min (HPLC)

MELTING POINT

32 ~ 34 C

 

TRANSPORT & REGULATORY INFORMATION

UN NO.

3261

HAZARD SYMBOL

8
PACKING GROUP II

 

SAFETY INFORMATION

HAZARD OVERVIEW

Combustible Liquid, Lachrymator.

GHS

 

SIGNAL WORD

Danger

PICTOGRAMS

HAZARD STATEMENTS

H314

P STATEMENTS

P280-P305 + P351 + P338-P310

EC DIRECTIVES

 

HAZARD CODES

RISK PHRASES

34-37

SAFETY PHRASES

26-36/37/39-45

 

PACKING

 

 

PRICE INFORMATION