ARGININE

PRODUCT IDENTIFICATION

CAS NO. 74-79-3; 142-49-4; 667422-95-9; 7004-12-8

ARGININE 

EINECS NO. 200-811-1
FORMULA H2NC(=NH)NH(CH2)3CH(NH2)COOH
MOL WT. 174.20

H.S. CODE

2925.29.9000

TOXICITY

 
SYNONYMS L-Arginine; (S)-2-Amino-5-((aminoiminomethyl)amino)pentanoic acid;
1-Amino-4-guanidovaleric acid; Arginina; Argininum; L-(+)-Arginine; Arg; S-(+)-Arginine; 5-((Aminoiminomethyl)amino)-L-norvaline; N5-(Aminoiminomethyl)-L-ornithine; L-alpha-Amino-delta-guanidinovaleric acid; (S)-2-Amino-5-((aminoiminomethyl)amino)pentanoic acid;
SMILES C(CCNC(N)=N)[C@@H](C(O)=O)N

CLASSIFICATION

Ammonia detoxicant, Diagnostic aid [pituitary function determination]

PHYSICAL AND CHEMICAL PROPERTIES

PHYSICAL STATE white crystalline powder
MELTING POINT 223 - 224 C
BOILING POINT

 

SPECIFIC GRAVITY 1.3
SOLUBILITY IN WATER 148.7 g/l at 20 C
pH  
VAPOR DENSITY

 

pKa 2.24 (at 20 C)
log Pow -4.20E+00 (Octanol-water)
VAPOR PRESSURE 8.87E-09 (mmHg)
HENRY'S LAW 1.83E-18 (atm-m3/mole at 25 C)
OH RATE 1.36E-10 (cm3/molecule-sec at 25 C Atmospheric)

AUTOIGNITION

 

NFPA RATINGS

Health: 1; Flammability: 0; Reactivity: 0

REFRACTIVE INDEX

 

FLASH POINT

 

STABILITY

Stable under ordinary conditions.

GENERAL DESCRIPTION & APPLICATIONS

L-arginine is a chemical building block called ¡°an amino acid.¡± It is obtained from the diet and is necessary for the body to make proteins. L-arginine is found in red meat, poultry, fish, and dairy products. It can also be made in a laboratory and used as medicine. L-arginine is used for heart and blood vessel conditions including congestive heart failure (CHF), chest pain, high blood pressure, and coronary artery disease. L-arginine is also used for recurrent pain in the legs due to blocked arteries (intermittent claudication), decreased mental capacity in the elderly (senile dementia), erectile dysfunction (ED), and male infertility. Some people use L-arginine for preventing the common cold, improving kidney function after a kidney transplant, high blood pressure during pregnancy (pre-eclampsia), improving athletic performance, boosting the immune system, and preventing inflammation of the digestive tract in premature infants. L-arginine is used in combination with a number of over-the-counter and prescription medications for various conditions. For example, L-arginine is used along with ibuprofen for migraine headaches; with conventional chemotherapy drugs for treating breast cancer; with other amino acids for treating weight loss in people with AIDS; and with fish oil and other supplements for reducing infections, improving wound healing, and shortening recovery time after surgery. Some people apply L-arginine to the skin to speed wound healing and for increasing blood flow to cold hands and feet, especially in people with diabetes. It is also used as a cream for sexual problems in both men and women. http://www.nlm.nih.gov

Wikipedia Linking: http://en.wikipedia.org/wiki/Arginine

Material Safety Data Sheet: http://www.chemcas.org/

Substrate of nitric oxide synthase, which is converted to citrulline and nitric oxide (NO). Induces insulin release by a nitric oxide-dependent mechanism.
SALES SPECIFICATION

APPEARANCE

White to off-white crystalline powder
SPECIFIC ROTATION +26.9° ~ +27.9° (20 C, c=8 HCl)

LOSS ON DRYING

0.5% max

RESIDUE ON IGNITION

0.1% max

HEAVY METAL

10ppm max

ASSAY

98.5 - 101.0%
TRANSPORTATION
PACKING
 
HAZARD CLASS Not regulated
UN NO.  
OTHER INFORMATION