BOC-L-PHENYLALANINE

PRODUCT IDENTIFICATION
CAS NO. 13734-34-4

BOC-L-PHENYLALANINE

EINECS NO. 237-305-5
FORMULA C14H19NO4
MOL WT. 265.31

H.S. CODE

  

TOXICITY

  
SYNONYMS Boc-Phe-OH; N-alpha-t-BOC-L-phenylalanine;
N-(tert-butoxycarbonyl)-L-phenylalanine; N-(terc-butoxicarbonil)-L-fenilalanina; N-(tert-butoxycarbonyl)-L-phénylalanine;
DERIVATION

 

CLASSIFICATION

  

PHYSICAL AND CHEMICAL PROPERTIES
PHYSICAL STATE White to off-white crystalline powder
MELTING POINT 86 - 88 C
BOILING POINT

 

SPECIFIC GRAVITY  
SOLUBILITY IN WATER

 

pH  
VAPOR DENSITY

 

AUTOIGNITION

  

NFPA RATINGS

 Health: 1; Flammability: 0; Reactivity: 0

REFRACTIVE INDEX

 

FLASH POINT

 

STABILITY

Stable under ordinary conditions. Moisture and light sensitive

GENERAL DESCRIPTION & APPLICATIONS
Phenylalanine is an essential amino acid obtained in the levo form by hydrolysis of proteins (as lactalbumin). Branched amino-acids (Valine, Isoleucine and Leucine ) with tryptophan and phenylalanine (aromatic side chain amino acids) contribute to the structure of protein by the tendency of its side chain composed only of carbon and hydrogen to participate in hydrophobic interactions which determines the tertiary structure of the peptide chain. In addition to its role in protein synthesis, it is the metabolic precursor of the non-essential amino acid tyrosine which makes hormones, such as norepinephrine and epinephrine in the normal body. Phenylalanine is also converted to phenylethylamine occuring naturally in the brain to elevate mood. It is used to treat depression, inflammation, chronic pain, Parkinson's disease. Phenylalanine is a key intermediate to make aspartame. N-alpha-t-BOC-L-phenylalanine is used in biological research of peptidomimetics. It is used to prepare unnatural and unusual amino acids and amino acid analogs as well as to modify peptides.
SALES SPECIFICATION

APPEARANCE

 White to off-white crystalline powder

ASSAY

 99.0% min
OPTICAL ROTATION [a]20 +24° ~ +26° (C=1 in EtOH)
SOLUTION CLARITY

clear

Fe

10ppm max
HEAVY METALS

10ppm max

As

2ppm max
LOSS ON DRYING

0.5% max
TRANSPORTATION
PACKING
 
HAZARD CLASS Not regulated
UN NO.  
OTHER INFORMATION
Hazard Symbols: XI, Risk Phrases: 36/37/38, Safety Phrases: 26-36

GENERAL DESCRIPTION OF AMINO ACID

Amino Acid

Abbreviation

Formula (Mol WT)

pK1

pK2

pKR

pI

Hydropathy Index

3-Letters

1-Letter

-COOH

-NH3+

R group
Alanine

Ala

A

 C3H7NO2 (89.09)

2.34

9.69

-

6.00

1.8
Arginine

Arg

R

 C6H14N4O2(174.20)

2.17

9.04

12.48

10.76

-4.5
Asparagine

Asn

N

 C4H8N2O3(132.12)

2.02

8.80

-

5.41

-3.5
Aspartic Acid

Asp

D

 C4H7NO4(133.10)

1.88

9.60

3.65

2.77

-3.5
Cysteine

Cys

C

 C3H7NO2S(240.30)

1.96

10.128

8.18

5.07

2.5
Glutamic Acid

Glu

E

 C5H9NO4(147.13)

2.19

9.67

4.25

3.22

-3.5
Glutamine

Gln

Q

 C5H10N2O3(146.15)

2.17

9.13

-

5.65

-3.5
Glycine

Gly

G

 C2H5O2(75.07)

2.34

9.60

-

5.97

-0.4
Histidine

His

H

 C6H9N3O2(155.16)

1.82

9.17

6.00

7.59

-3.2
Isoleucine

Ile

I

 C6H13NO2(131.18)

2.36

9.60

-

6.02

4.5
Leucine

Leu

L

 C6H13NO2(131.18)

2.36

9.60

-

5.98

3.8
Lysine

Lys

K

 C6H14N2O2(146.19)

2.18

8.95

10.53

9.74

-3.9
Methionine

Met

M

 C5H11NO2S(149.21)

2.28

9.21

-

5.74

1.9
Phenylalanine

Phe

F

 C9H11NO2(165.19)

1.83

9.13

-

5.48

2.8
Proline

Pro

P

 C5H9NO2(115.13)

1.99

10.60

-

6.30

1.6
Serine

Ser

S

 C3H7NO3(105.19)

2.21

9.15

-

5.58

-0.8
Threonine

Thr

T

 C4H9NO3(119.12)

2.09

9.10

-

5.60

-0.7
Tryptophan

Trp

W

 C11H10N2O2(204.23)

2.83

9.39

-

5.89

-0.9
Tyrosine

Tyr

Y

 C9H11NO3(181.19)

2.20

9.11

10.07

5.66

-1.3
Valine

Val

V

 C5H11NO2(117.15)

2.32

9.62

-

5.96

4.2