Fmoc-Gly-Gly-OH

Synonyms. Fmoc-Gly-Gly-OH; Fmoc-glycyl-glycine; Fmoc-(Gly)2-OH; N-alpha-(9-Fluorenylmethyloxycarbonyl)-glycinyl-glycin; N-[(9H-Fluoren-9-ylmethoxy)carbonyl]glycyl-glycine ; N-9-Fluorenylmethoxycarbonylglycylglycine  2-((2-(9H-Fluoren-9-ylmethoxycarbonylamino)acetyl)amino)acetic acid;

Fmoc-Gly-Gly-OH

 

PRODUCT IDENTIFICATION

CAS RN

35665-38-4

EINECS RN

 

FORMULA

C19H18N2O5

MOLE WEIGHT

354.36

H.S CODE

2924.19.1150

SMILES

C1=CC=C2C(=C1)C(C3=CC=CC=C32)COC(=O)NCC(=O)NCC(=O)O

CLASSIFICATION

Dipeptide

EXTRA NOTES

 

 

PHYSICAL AND CHEMICAL PROPERTIES

PHYSICAL STATE.

white powder

MELTING POINT

 

BOILING POINT

 

DENSITY

1.34

SOLUBILITY IN WATER

 

SOLVENT SOLUBILITY  

VAPOR DENSITY

 

log P(octanol-water)

 

VAPOR PRESSURE

 

AUTOIGNITION TEMP

 
pH

 

REFRACTIVE INDEX

 

FLASH POINT

 

 

STABILITY AND REACTIVITY
STABILITY Stable under normal conditions.

INCOMPATIBLE MATERIALS

Strong oxidizing agents

POLYMERIZATION

Has not been reported

NFPA RATINGS

Health: 1; Flammability: 0; Instability: 0;

 

EXTERNAL LINKS & GENERAL DESCRIPTION

Wikipedia Linking - Dipeptide

Google Scholar Search

PubChem Compound Summary - Fmoc-Gly-Gly-OH

http://www.ncbi.nlm.nih.gov/ - Fmoc-Gly-Gly-OH

http://www.peptideguide.com/
Dipeptide (DP) is actually one molecule, which consists of 2 amino acids that are joined by a single peptide bond. Since it consists of 2 different amino acids, it can have different sequences, like Ala-Gly or Gly-Ala. Such dipeptides would have different chemical and biological properties. The matter is that if written left to right in Gly-Ala, the glycine has the 'free' amine terminal end, while alanine has the 'free' carboxyl acid terminal end. Dipeptide can be produced in different ways, which are generally divided into 3 methods: chemical synthesis, chemoenzymatic synthesis, and enzymatic synthesis. Meanwhile, the function of di-peptides can be viewed from two points: as a derivative of amino acid and as the dipeptide itself. The first one is quite easy to understand, since although DPs and the constitutive amino acids feature different physicochemical properties, they should still share the same physiological effects, because dipeptides are degraded into the individual amino acids in organisms. For instance, L-Glutamine is heat labile, but L-alanyl-L-glutamine is more tolerant to heat. Another good example is solubility: while Tyr is practically insoluble, you can dissolve Ala-Tyr up to 14 g/L. The most interesting fact is that a number of dipeptides are more soluble than each of the constitutive amino acids. For example, the solubilities of Ala and Gln are 89 and 36 g/L accordingly, but that of Ala-Gln is 586 g/L! Considering these properties and the fact that Ala-Gln and Gly-Tyr are quickly degraded into the individual amino acids when taken into the body, these dipeptides are used as components of patient infusions.

 

 

SALES SPECIFICATION

APPEARANCE

white powder

PURITY

98.0% min (HPLC)

 

TRANSPORT & REGULATORY INFORMATION

UN NO.

Not regulated

HAZARD SYMBOL

 
PACKING GROUP  

 

SAFETY INFORMATION

HAZARD OVERVIEW

Not known

GHS

 

SIGNAL WORD

 

PICTOGRAMS

 

HAZARD STATEMENTS

 

P STATEMENTS

 

EC DIRECTIVES

 

HAZARD CODES

 

RISK PHRASES

 

SAFETY PHRASES

24/25

 

PACKING

 

 

PRICE INFORMATION