N-BOC-4-(AMINOMETHYL)PIPERIDINE

Synonyms: 4-(Aminomethyl)piperidine-1-carboxylic acid tert-butyl ester; 1-Boc-4-(Aminomethyl)piperidine; tert-Butyl 4-(aminomethyl)piperidine-1-carboxylate; N-Boc-4-(Aminomethyl)piperidine; 1,1-Dimethylethyl 4-(aminomethyl)-1-piperidinecarboxylate; N-(tert-Butoxycarbonyl)-4-aminomethylpiperidine;

N-BOC-4-(AMINOMETHYL)PIPERIDINE

 

PRODUCT IDENTIFICATION

CAS RN

144222-22-0

EINECS RN

 

FORMULA

C11H22N2O2

MOLE WEIGHT

214.30

SMILES

 
H.S. CODE 2933.39.6190

CLASSIFICATION

Piperidine, Pyrrolidine, Azetidine

EXTRA NOTES

 

 

PHYSICAL AND CHEMICAL PROPERTIES

PHYSICAL STATE

clear liquid

MELTING POINT

 

BOILING POINT

237 - 238 C

DENSITY

1.013

SOLUBILITY IN WATER

 

SOLVENT SOLUBILITY

 

pH

 

REFRACTIVE INDEX

1.473

FLASH POINT

> 110 C

 

STABILITY AND REACTIVITY
STABILITY Stable under normal conditions

INCOMPATIBLE MATERIALS

Oxidizing agents.

DECOMPOSITION PRODUCTS

Carbon oxides, nitrogen oxides, possibly hydrogen cyanide (HCN)

POLYMERIZATION

Has not been reported.

NFPA RATINGS

Health: 2. Flammability: 0, Reactivity: 0

 

SAFETY INFORMATION

HAZARD NOTES

Harmful by inhalation. Harmful in contact with skin and if swallowed.

EYE

Cause eye irritation.

SKIN

Harmful if absorbed through skin. May cause skin irritation.

INGESTION

Toxic if swallowed.

INHALATION

Harmful if inhaled. May cause respiratory tract irritation.

CHRONIC

 

PICTOGRAMS

GHS07

HAZARD STATEMENTS

H315 Causes skin irritation
H319 Causes serious eye irritation.
H335 May cause respiratory irritation.

PRECAUTIONARY STATEMENTS

P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P321 Specific treatment (see label).
P405 Store locked up.
P501 Dispose of contents/container in accordance with local/regional/national/international regulations.

WATER HAZARD

class 1

 

EXTERNAL LINKS & GENERAL DESCRIPTION

http://www.sigmaaldrich.com/
Application: Precursor in the preparation of a variety of different protein agonists or antagonists including: (Kinesin spindle protein inhibitors with potential anticancer activity, Orphan G-protein coupled receptor GPR119 agonist with antidiabetic potential, Pim-1 inhibitors, Aspartic acid protease inhibitors. Reactant involved in enantioselective synthesis of N-alkyl terminal aziridines

 

TRANSPORT & REGULATORY INFORMATION

UN NO.

 
HAZARD CLASS

 

PACKING GROUP

 

HAZARD SYMBOL

XI Irritant

RISK PHRASES

36/37/38 Irritating to eyes, respiratory system and skin.

SAFETY PHRASES

26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice
36 Wear suitable protective clothing

 

SALES SPECIFICATION

APPEARANCE

clear to pale yellow liquid

PURITY 97.0%

 

PRICE INFORMATION