N-tert-BOC-L-PHENYLALANINOL

PRODUCT IDENTIFICATION

CAS NO. 66605-57-0

N-tert-BOC-L-PHENYLALANINOL

EINECS NO.  
FORMULA C6H5CH2CH[NHCO2C(CH3)3]CH2OH
MOL WT. 251.32

H.S. CODE

 

TOXICITY

 

SYNONYMS N-t-Butoxycarbonyl-L-phenylalaninol; N-Boc-L-Phenylalaninol
Boc-(S)-2-amino-3-phenyl-1-propanol; N-t-Butoxycarbonyl-L-phenylalaninol; (S)-2-(BOC-amino)-3-phenyl-1-propanol; N-(tert-Butoxycarbonyl)-L-phenylalaninol;

DERIVATION

 

CLASSIFICATION

 

PHYSICAL AND CHEMICAL PROPERTIES

PHYSICAL STATE

white to off-white powder

MELTING POINT 94 - 96 C
BOILING POINT  
SPECIFIC GRAVITY  
SOLUBILITY IN WATER Insoluble
pH  
VAPOR DENSITY

 

AUTOIGNITION

 

NFPA RATINGS

 

REFRACTIVE INDEX

 
FLASH POINT

 

STABILITY

Stable under ordinary conditions.

GENERAL DESCRIPTION

Chiral amino alcohol possessing both amine and alcohol is a structural motif for the compounds which have important biological and pharmacological functions within the body as inhibitor of aspartyl proteases, aldose reductase, b-amyloid peptide formation, and dopamine D4 antagonists. The chiral amino alcohol also exhibits anti-inflammatory, anesthetic, antipasmodic, hepatotoxic, anti-diabetic, anti-obesity,and anti-depressant activities. Chiral amino alcohols and their N-protected derivatives (Cbz, t-Boc, and Fmoc) are versatile building blocks, auxiliaries, ligand or resolving agent in asymmetric synthesis for biological and pharmaceutical researches. applications are present in the field of antitumor, anesthetic, antipasmodic, hepatotoxic, antiinflammatory or anti-HIV activities.  Their derivatives include the forms of;

  • C-terminal peptibiols
  • Amphiphylic antibacterial peptides
  • Oligocarbamates
  • Analogs of peptides
  • Aziridines, Halogen aminoalkyls
  • Enantiomerical alpha-alkyl mono and diamines
  • Enantiomerical beta-substituted amines
  • Enantiomerical beta-amino acids beta-amino sulfoxides, beta-amino sulfides and
  • beta-amino thiols.
  • The precursors of diverse compounds such as statines, sphingolipides and peptide isosteres.
SALES SPECIFICATION

APPEARANCE

white to off-white powder

CHEMICAL PURITY

98.0% min

OPTICAL PURITY

98.0% min
OPTICAL ROTATION -25° ~ -29° (C=1, CHCl3)
TRANSPORTATION
PACKING
 
HAZARD CLASS  
UN NO.  
OTHER INFORMATION
Hazard Symbols: XI, Risk Phrases: 36/37/38, Safety Phrases: 22-24/26