Z-Gly-Gly-Leu-pNA

Synonyms. Z-Gly-Gly-Leu-pNA; Benzyloxycarbonyl-glycyl-glycyl-leucine-4-nitroanilide; N-Benzyloxycarbonylglycyl-glycyl-leucine-4-nitroanilide; Z-Gly-gly-leu-4-nitroanilide; N-((Phenylmethoxy)carbonyl)glycylglycyl-N-(4-nitrophenyl)-L-leucinamide;

Z-Gly-Gly-Leu-pNA

 

PRODUCT IDENTIFICATION

CAS RN

53046-98-3

EINECS RN

 

FORMULA

C24H29N5O7

MOLE WEIGHT

499.52

H.S CODE

2924.29.7100

SMILES

C([C@@H](Nc1ccc(cc1)[N+](=O)[O-])CC(C)C)(=O)NC(CNC(CNC(=O)OC c1cc ccc1)=O)=O

CLASSIFICATION

Tripeptide

EXTRA NOTES

A sensitive chromogenic substrate for subtilisins and neutral endopeptidases.

 

PHYSICAL AND CHEMICAL PROPERTIES

PHYSICAL STATE.

white powder

MELTING POINT

 

BOILING POINT

 

DENSITY

 

SOLUBILITY IN WATER

 

SOLVENT SOLUBILITY  

VAPOR DENSITY

 

log P(octanol-water)

 

VAPOR PRESSURE

 

AUTOIGNITION TEMP

 
pH

 

REFRACTIVE INDEX

 

FLASH POINT

 

 

STABILITY AND REACTIVITY
STABILITY Stable under normal conditions.

INCOMPATIBLE MATERIALS

Strong oxidizing agents

POLYMERIZATION

Has not been reported

NFPA RATINGS

Health: 1; Flammability: 0; Instability: 0;

 

EXTERNAL LINKS & GENERAL DESCRIPTION

Wikipedia Linking - Tripeptide

Google Scholar Search

PubChem Compound Summary - Z-Gly-Gly-Leu-pNA

http://www.ncbi.nlm.nih.gov/ - Z-Gly-Gly-Leu-pNA

http://www.peptideguide.com/
Application of Synthetic Peptides: Synthetic peptides are widely used for the following purposes: - To verify the structure of naturally occurring peptides as determined by degradation techniques
- To study the relationship between structure and activity of biologically active protein and peptides and establish their molecular mechanisms
- To develop new peptide-based immunogens, hormones, vaccines, etc
Peptide Drugs: Peptide drugs are either naturally-occurring peptides or altered natural peptides. There are many naturally-occurring peptides that are biologically active. If a patient does not naturally produce a peptide that they need, this peptide can be synthesized and given to them. In addition, the amino acids in an active peptide can be altered to make analogues of the original peptide. If the analogue is more biochemical active than the original peptide it is known as an agonist and if it has the reverse effect is known as an antagonist.
Diagnostic Peptides: Peptides can be designed that change color under certain conditions, and these can be used for diagnostic purposes. For example, a chromogenic peptide substrate can readily detect the presence, absence and varying blood levels of enzymes that control blood pressure and blood clotting ability.

Local:
Peptide is the members of the compounds composed of two or more amino acids joined by the linking between one amino acid residue and the carboxyl group of the next amino acid by hydrolysis into linear, branched or cyclical structures. The link is an amide bond, and is sometimes referred to as a peptide bond. Peptides are playing a promising role in the molecular biology and in the creating medicines. Peptides are used in the study of protein structure and function, antibodies for the inhibition of cancer, for the study of protein structure and function research. Peptides are also used as instrumental in mass spectrometry. Biological activities of peptide are applicable in the fields of nutrition, medicine, and cosmetics.

  • Dipeptide: a molecule consisting of two amino acids
  • Tripeptide a molecule consisting of three amino acids
  • Octapeptide: a molecule consisting of eight amino acids
  • Oligopeptide: a polypeptide composed of approximately 2-12 amino acids length (or 3 to 40 component amino acids)
  • Polypeptide: a single molecule composed of approximately 13 or more amino acids.
  • Protein: a linear polypeptides that are normally synthesized on ribosomes.

 

SALES SPECIFICATION

APPEARANCE

white powder

PURITY

98.0% min (HPLC)

 

TRANSPORT & REGULATORY INFORMATION

UN NO.

Not regulated

HAZARD SYMBOL

 
PACKING GROUP  

 

SAFETY INFORMATION

HAZARD OVERVIEW

Not known

GHS

 

SIGNAL WORD

 

PICTOGRAMS

 

HAZARD STATEMENTS

 

P STATEMENTS

 

EC DIRECTIVES

 

HAZARD CODES

 

RISK PHRASES

 

SAFETY PHRASES

24/25

 

PACKING

 

 

PRICE INFORMATION