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ARECOLINE |
| Synonyms. Arecoline; 1,2,5,6-Tetrahydro-1-methyl-3-pyridinecarboxylic acid methyl ester; 1,2,5,6-Tetrahydro-1-methylnicotinic acid methyl ester; 1-Methyl-delta(3,4)tetrahydro-3-pyridinecarboxylate; Arecaidine methyl ester; Arecaline; Arecholine; Arecolin; Arecoline; Arecoline base; Arekolin; Methyl 1,2,5,6-tetrahydro-1-methylnicotinate; Methyl N-methyl-1,2,5,6-tetrahydronicotinate; Methyl N-methyltetrahydronicotinate; Methylarecaiden; N-Methyltetrahydronicotinic acid, methyl ester; N-Methyltetrahydropyridine-beta-carboxylic acid methyl ester; Methylarecaiden; |
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| PRODUCT IDENTIFICATION | |
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CAS RN |
63-75-2 (net), 300-08-3 (HBr) |
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EINECS RN |
200-565-5 (net), 206-087-3 (HBr) |
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FORMULA |
C8H13NO2 |
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MOLE WEIGHT |
155.19 |
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H.S CODE |
2939.99.0000 |
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SMILES |
C1[N@@](CC(=CC1)C(OC)=O)C |
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CLASSIFICATION |
Muscarinic agonist, Nicotinic agonist, Alkaloid |
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EXTRA NOTES |
An alkaloid obtained from the betel nut (Areca catechu), fruit of a palm tree. It is an agonist at both muscarinic and nicotinic acetylcholine receptors. It is used in the form of various salts as a ganglionic stimulant, a parasympathomimetic, and a vermifuge, especially in veterinary practice. It has been used as a euphoriant in the Pacific Islands. MeSH |
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| PHYSICAL AND CHEMICAL PROPERTIES | |
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PHYSICAL STATE. |
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MELTING POINT |
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BOILING POINT |
209 C |
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DENSITY |
1.0495 |
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SOLUBILITY IN WATER |
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| SOLVENT SOLUBILITY |
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VAPOR DENSITY |
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log P(octanol-water) |
0.35 |
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VAPOR PRESSURE |
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AUTOIGNITION TEMP |
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| pK |
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REFRACTIVE INDEX |
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FLASH POINT |
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| STABILITY AND REACTIVITY | |
| STABILITY | Stable under normal conditions. |
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INCOMPATIBLE MATERIALS |
Strong oxidizing agents |
| POLYMERIZATION |
Has not been reported |
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NFPA RATINGS |
Health: 1, Flammability: 0, Reactivity: 0 |
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| EXTERNAL LINKS & GENERAL DESCRIPTION |
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USA.gov - Arecoline Wikipedia Linking - Arecoline Google Scholar Search - Arecoline U.S. National Library of Medicine - Arecoline PubChem Compound Summary - Arecoline Drug Bank - Arecoline KEGG (Kyoto Encyclopedia of Genes and Genomes) - Arecoline ChEBI (http://www.ebi.ac.uk/chebi/) - Arecoline NCBI (http://www.ncbi.nlm.nih.gov/) - Arecoline |
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| SALES SPECIFICATION (HBr) | |
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APPEARANCE |
white powder |
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ASSAY |
98% min |
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MELTING POINT |
172 ~ 176 C |
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| TRANSPORT & REGULATORY INFORMATION | |
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UN NO. |
2811 |
| HAZARD CLASS |
6.1 |
| PACKING GROUP | III |
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| SAFETY INFORMATION | |
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HAZARD OVERVIEW |
GHS (Globally Harmonised System) Classification: Acute toxicity (Oral). Hazard statements: Toxic if swallowed. |
| SIGNAL WORD | Danger |
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PICTOGRAMS |
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HAZARD STATEMENTS |
H301 |
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P STATEMENTS |
P301 + P310 |
| EC DIRECTIVES |
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| HAZARD CODES |
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RISK PHRASES |
22 |
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SAFETY PHRASES |
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| PACKING |
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Preserve in light-resistant and well-closed containers |
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