ASIATIC ACID

Synonyms. Asiatic acid; (2alpha,3beta,4alpha)-2,3,23-Trihydroxyurs-12-en-28-oic acid; (1S,2R,4aS,6aR,6aS,6bR,8aR,9R,10R,11R,12aR,14bS)-10,11-Dihydroxy- 9-(hydroxymethyl)-1,2,6a,6b,9, 12a-hexamethyl-2,3,4,5,6,6a,7,8,8a,10,11,12,13, 14b-tetradecahydro-1H-picene-4a-carboxylic acid;

ASIATIC ACID

Click for original image

 

PRODUCT IDENTIFICATION

CAS RN

464-92-6

EINECS RN

 

FORMULA

C30H48O5

MOLE WEIGHT

488.70

H.S CODE

2918.29.6500

SMILES

C1[C@@]2(C)[C@H]([C@](C)(CO)[C@H](O)[C@@H]1O)CC[C@@]1([C@ @H] 2CC=C2[C@@]1(C)CC[C@@]1([C@H]2[C@H]([C@@H](CC1)C) C) C(O)=O)C

CLASSIFICATION

Phytochemical, Antioxidant, Anti-inflammatory, Neuroprotective, Pentacyclic triterpene

EXTRA NOTES

Triterpene acid

 

PHYSICAL AND CHEMICAL PROPERTIES

PHYSICAL STATE.

white to off-white powder

MELTING POINT

325 ~ 330 C

BOILING POINT

 

DENSITY

 

SOLUBILITY IN WATER

 

SOLVENT SOLUBILITY

 

VAPOR DENSITY

 

log P(octanol-water)

 

VAPOR PRESSURE

 

AUTOIGNITION TEMP

 
pK

 

REFRACTIVE INDEX

 

FLASH POINT

 

 

STABILITY AND REACTIVITY
STABILITY Stable under normal conditions.

INCOMPATIBLE MATERIALS

Strong oxidizing agents

POLYMERIZATION

Has not been reported

NFPA RATINGS

Health: 1, Flammability: 0, Reactivity: 0

 

EXTERNAL LINKS & GENERAL DESCRIPTION

USA.gov - Asiatic acid

Google Scholar Search - Asiatic acid

U.S. National Library of Medicine - Asiatic acid

PubChem Compound Summary - Asiatic acid

KEGG (Kyoto Encyclopedia of Genes and Genomes) -  Asiatic acid

http://www.ebi.ac.uk/chebi/ -  Asiatic acid

http://www.ncbi.nlm.nih.gov/ -  Asiatic acid

Material Safety Data Sheet - Asiatic acid

Human Metabolome Database - Asiatic acid

Hazardous Substances Data Bank - Asiatic acid

EPA - Substance Registry Services - Asiatic acid

http://www.sigmaaldrich.com/
Application: Starting material for asiatic acid derivative synthesis for use as: ·Anticancer agents ·Glycogen phosphorylase inhibitors ·Hepatoprotectants

 

SALES SPECIFICATION

APPEARANCE

white to off-white powder

ASSAY

98% min

MELTING POINT

> 300 C

LOSS ON DRYING

1% max

HEAVY METALS

10ppm max

 

TRANSPORT & REGULATORY INFORMATION

UN NO.

 

HAZARD CLASS

 

PACKING GROUP  

 

SAFETY INFORMATION

HAZARD OVERVIEW

GHS (Globally Harmonised System) Classification: Not a dangerous substance. Potential Health Effects: Eyes - May cause eye irritation. Skin - May be harmful if absorbed through skin May cause skin irritation. Inhalation - May be harmful if inhaled. May cause respiratory tract irritation. Ingestion - May be harmful if swallowed.

HAZARD CODES

 

RISK PHRASES

 

SAFETY PHRASES

 

 

PACKING

Preserved in light-resistant and well-closed bottles