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BERGENIN |
| Synonyms. Bergenin; 4-Methoxy-2-(tetrahydro-3,4,5-trihydroxy- 6-(hydroxymethyl)pyran-2-yl) alpha-resorcylic acid gamma lactone; 3,4,4a,10b-Tetrahydro-3,4,8,10-tetrahydroxy-2 -(hydroxymethyl)- 9-methoxypyrano(3,2-c)(2)benzopyran-6(H)-one; Cuscutin; Corylopsin; Peltophorin; Hydropyrano[3,2-c]isochromen-6(2H)-one; Bergenit Ardisic Acid B; |
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| PRODUCT IDENTIFICATION | |
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CAS RN |
477-90-7 |
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EINECS RN |
201 |
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FORMULA |
C14H16O9 |
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MOLE WEIGHT |
328.27 |
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H.S CODE |
2932.20.3000 |
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SMILES |
Oc1cc2c(c(O)c1OC)[C@@H]1O[C@@H]([C@H]([C@@H]([C@H]1OC2 =O)O) O)CO |
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CLASSIFICATION |
Antinociceptive, Anti-inflammatory |
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EXTRA NOTES |
Bergenin displays antinociceptive and anti-inflammatory properties, in addition to its use in folk medicines as a potent hepatoprotective agent. Bergenin acts by inhibiting the formation of interleukin 1beta and TNF-α, which suggests its potential use for controling inflammatory pain. sigmaaldrich |
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| PHYSICAL AND CHEMICAL PROPERTIES | |
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PHYSICAL STATE |
white to off-white crystalline powder |
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MELTING POINT |
237 ~ 240 C |
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BOILING POINT |
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DENSITY |
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SOLUBILITY IN WATER |
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| SOLVENT SOLUBILITY |
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VAPOR DENSITY |
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log P(octanol-water) |
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VAPOR PRESSURE |
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AUTOIGNITION TEMP |
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| pK |
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REFRACTIVE INDEX |
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FLASH POINT |
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| STABILITY AND REACTIVITY | |
| STABILITY | Stable under normal conditions. |
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INCOMPATIBLE MATERIALS |
Strong oxidizing agents. |
| POLYMERIZATION |
Has not been reported |
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NFPA RATINGS |
Health: 1, Flammability: 0, Reactivity: 0 |
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| EXTERNAL LINKS & GENERAL DESCRIPTION |
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USA.gov - Bergenin Wikipedia Linking - Bergenin Google Scholar Search - Bergenin U.S. National Library of Medicine - Bergenin PubChem Compound Summary - Bergenin KEGG (Kyoto Encyclopedia of Genes and Genomes) - Bergenin ChEBI (http://www.ebi.ac.uk/chebi/) - Bergenin NCBI (http://www.ncbi.nlm.nih.gov/) - Bergenin |
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| SALES SPECIFICATION | |
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APPEARANCE |
white to off-white crystalline powder |
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ASSAY |
98% min |
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MELTING POINT |
235 ~ 240 C |
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HEAVY METALS |
10ppm max |
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| TRANSPORT & REGULATORY INFORMATION | |
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UN NO. |
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| HAZARD CLASS |
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| PACKING GROUP | |
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| SAFETY INFORMATION | |
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HAZARD OVERVIEW |
GHS (Globally Harmonised System) Classification: Skin irritation. Eye irritation. Specific target organ toxicity |
| SIGNAL WORD | Warning |
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PICTOGRAMS |
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HAZARD STATEMENTS |
H315-H319-H335 |
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P STATEMENTS |
P261-P305 + P351 + P338 |
| EC DIRECTIVES |
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| HAZARD CODES |
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RISK PHRASES |
36/37/38 |
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SAFETY PHRASES |
26 |
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| PACKING |
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Preserved in light-resistant and well-closed bottles |
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