CYTOCHALASIN C

Synonyms. Cytochalasin C; (3S-(3R*,3aS*,6R*,6aS*,7E,10R*,12S*,13E,15S*,15aS*))-15-(Acetyloxy)-3,3a,6,6a, 9,10,12,15- octahydro- 6,12-dihydroxy-4,5,10,12-tetramethyl-3-(phenylmethyl)-1H-cycloundec(d)isoindole- 1,11(2H)-dione; 7(S),18-Dihydroxy-16(S),18(R)-dimethyl-10-phenyl(11)cytochalasa-5,13(E),19(E)-triene-1,17-dione 21(R)-acetate;

CYTOCHALASIN C

Click for original image

 

PRODUCT IDENTIFICATION

CAS RN

22144-76-9

EINECS RN

244-803-6

FORMULA

C30H37NO6

MOLE WEIGHT

507.62

H.S CODE

2933.79.0800

SMILES

N1[C@@H]([C@@H]2C(=C([C@H]([C@H]3[C@]2(C1=O)[C@@H](C=C[ C@@] (C([C@H](CC=C3)C) =O)(C)O)OC(=O)C)O)C)C)Cc1ccccc1

CLASSIFICATION

Mycotoxin, Actin inhibitor

EXTRA NOTES

 

 

PHYSICAL AND CHEMICAL PROPERTIES

PHYSICAL STATE.

white powder

MELTING POINT

2 ~ C

BOILING POINT

2 ~ C

DENSITY

 

SOLUBILITY IN WATER

 

SOLVENT SOLUBILITY

 

VAPOR DENSITY

 

log P(octanol-water)

 

VAPOR PRESSURE

 

AUTOIGNITION TEMP

 
pK

 

REFRACTIVE INDEX

 

FLASH POINT

 

 

STABILITY AND REACTIVITY
STABILITY Stable under normal conditions.

INCOMPATIBLE MATERIALS

Strong oxidizing agents

POLYMERIZATION

Has not been reported

NFPA RATINGS

Health: 1, Flammability: 0, Reactivity: 0

 

EXTERNAL LINKS & GENERAL DESCRIPTION

USA.gov - Cytochalasin C

Wikipedia Linking - Cytochalasin

Google Scholar Search - Cytochalasin C

U.S. National Library of Medicine - Cytochalasin C

PubChem Compound Summary - Cytochalasin C

KEGG (Kyoto Encyclopedia of Genes and Genomes) -  Cytochalasin C

NCBI (http://www.ncbi.nlm.nih.gov/) -  Cytochalasin C

Cytochalasin A is a metabolite of the fungus Drechslera (previously Heiminthosporium) dematioideum. Cytochalasin A is sulfhydryl-reactive, and was shown to inhibit growth and sugar uptake in a Saccharomyces strain. Unlike Cytochalasin B, Cytochalasin C and Cytochalasin D are isomeric metabolites of Metarrhizium anisopliae. Cytochalasin D possesses antibiotic and antitumor activity. It also impairs maintenance of long term potentiation (LTP) of actin filaments. It is implicated in promoting conditions favorable for depolymerizing actin. sigmaaldrich

 

SALES SPECIFICATION

APPEARANCE

white powder

ASSAY

98% min

 

TRANSPORT & REGULATORY INFORMATION

UN NO.

1544

HAZARD CLASS

6.1

PACKING GROUP II

 

SAFETY INFORMATION

HAZARD OVERVIEW

GHS (Globally Harmonised System) Classification: Acute toxicity (Oral). Acute toxicity (Inhalation). Acute toxicity (Dermal). Reproductive toxicity. Hazard statements: Fatal if swallowed or in contact with skin. Fatal if inhaled. Suspected of damaging fertility or the unborn child.

SIGNAL WORD Danger

PICTOGRAMS

HAZARD STATEMENTS

H300 + H310-H330-H361

P STATEMENTS

P260-P264-P280-P284-P302 + P350-P310

EC DIRECTIVES

 

HAZARD CODES

RISK PHRASES

63-26/27/28

SAFETY PHRASES

28-36/37-45

 

PACKING

Preserve in light-resistant and well-closed containers