D-KYNURENINE

Synonyms. D-Kynurenine; (R)-2-Amino-4-(2-aminophenyl)-4-oxobutanoic acid; D-2-Amino-4-(2-aminophenyl)-4-oxobutanoic acid; beta-Anthraniloyl-D-alanine; (2R)-2-Amino-4-(2-aminophenyl)-4-oxobutanoic acid; beta-Anthraniloyl-D-alanine;

D-KYNURENINE

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PRODUCT IDENTIFICATION

CAS RN

343-65-7 (DL), 2922-83-0 (L), 13441-51-5 (D)

EINECS RN

 

FORMULA

C10H12N2O3

MOLE WEIGHT

208.21

H.S CODE

2922.50.3500

SMILES

C1=CC=C(C(=C1)C(=O)CC(C(=O)O)N)N

CLASSIFICATION

Metabolite

EXTRA NOTES

Biochem/physiol Actions:D-Kynurenine may be used along with L-kynurenine to assess the specificity and kinetics of kynurenine metabolizing enzymes. D-Kynurenine is used to study the selectivity and activity of the G protein-coupled receptor, GPR109B. D-Kynurenine is used as a substrate in a fluorometric assay of D-amino acid oxidase[sigmaaldich]

 

PHYSICAL AND CHEMICAL PROPERTIES

PHYSICAL STATE

white to off-white crystalline powder

MELTING POINT

 

BOILING POINT

 

DENSITY

 

SOLUBILITY IN WATER

 

SOLVENT SOLUBILITY

 

VAPOR DENSITY

 

log P(octanol-water)

 

VAPOR PRESSURE

 

AUTOIGNITION TEMP

 
pK

 

REFRACTIVE INDEX

 

FLASH POINT

 

 

STABILITY AND REACTIVITY
STABILITY Stable under normal conditions.

INCOMPATIBLE MATERIALS

Strong oxidizing agents.

POLYMERIZATION

Has not been reported

NFPA RATINGS

Health: 1, Flammability: 1, Reactivity: 0

 

EXTERNAL LINKS & GENERAL DESCRIPTION

USA.gov - D-Kynurenine

Wikipedia Linking - Kynurenine

Google Scholar Search - D-Kynurenine

PubChem Compound Summary - D-Kynurenine

Drug Bank -  D-Kynurenine

KEGG (Kyoto Encyclopedia of Genes and Genomes) -  D-Kynurenine

ChEBI (http://www.ebi.ac.uk/chebi/) -  N-formyl-D-kynurenine

NCBI (http://www.ncbi.nlm.nih.gov/) -  D-Kynurenine

Material Safety Data Sheet - D-Kynurenine

Human Metabolome Database - D-Kynurenine

 

SALES SPECIFICATION

APPEARANCE

white to off-white crystalline powder

ASSAY

98% min

LOSS ON DRYING

1.0% max

HEAVY METALS

20ppm max

 

TRANSPORT & REGULATORY INFORMATION

UN NO.

 

HAZARD CLASS

 

PACKING GROUP  

 

SAFETY INFORMATION

HAZARD OVERVIEW

GHS (Globally Harmonised System) Classification: Not a dangerous substance. Potential Health Effects: Eyes - May cause eye irritation. Skin - May be harmful if absorbed through skin May cause skin irritation. Inhalation - May be harmful if inhaled. May cause respiratory tract irritation. Ingestion - May be harmful if swallowed.

HAZARD CODES

 

RISK PHRASES

 

SAFETY PHRASES

 

 

PACKING

Preserved in light-resistant and well-closed bottles

 

PRICE INFORMATION