D-MANNOSE

Synonyms. D-Mannose; D-(+)-Mannose; D-Mannopyranose; (+)-Mannose; Carubinose; Seminose; D-Mannopyranose; (+)-Mannose; (3S,4S,5S,6R)-6-(Hydroxymethyl)oxane-2,3,4,5-tetrol;

D-MANNOSE

 

PRODUCT IDENTIFICATION

CAS RN

3458-28-4

EINECS RN

 222-392-4

FORMULA

 C6H12O6

MOLE WEIGHT

 180.16

H.S CODE

 2940.00.6000

SMILES

 O1[C@@H]([C@H]([C@@H]([C@@H](O)[C@@H]1O)O)O)CO

CLASSIFICATION

Carbohydrate

EXTRA NOTES

 Other RN: 147-74-0, 50986-23-7, 50986-24-8

 

PHYSICAL AND CHEMICAL PROPERTIES

PHYSICAL STATE

white crystalline powder

MELTING POINT

132 ~ 134 C

BOILING POINT

  

DENSITY

 

SOLUBILITY IN WATER

 

SOLVENT SOLUBILITY  

VAPOR DENSITY

 

log P(octanol-water)

 -2.43

AUTOIGNITION TEMP

  
pKa

12.92

REFRACTIVE INDEX

 

FLASH POINT

 

 

STABILITY AND REACTIVITY
STABILITY Stable under normal conditions.

INCOMPATIBLE MATERIALS

Strong oxidizing agents

POLYMERIZATION

Has not been reported

NFPA RATINGS

Health: 0; Flammability: 0; Instability: 0;

 

EXTERNAL LINKS & GENERAL DESCRIPTION

Wikipedia Linking - Mannose

Google Scholar Search - D-Mannose

Drug Information Portal (U.S. National Library of Medicine) - D-Mannose

PubChem Compound Summary - D-Mannose

Drug Bank -  D-Mannose

KEGG (Kyoto Encyclopedia of Genes and Genomes) - D-Mannose

http://www.ebi.ac.uk/ - D-Mannose

http://www.ncbi.nlm.nih.gov/ - D-Mannose

http://toxnet.nlm.nih.gov/
Hazardous Substances Data Bank - D-Mannose

http://ajcn.nutrition.org/
Mannose is involved in an extensive series of metabolic transformations being incorporated into glycoproteins and glycolipids or formed into fucose that is then incorporated into glycoproteins. The primary source of mannose is glucose. Mannose occurs as the free sugar in peaches, apples, and oranges but is absorbed from the gastrointestinal tract of rats at only about 12% of the rate of glucose. Mannose conceivably might be liberated from dietary glycoproteins and glycolipids by the action of mannosidase in the gastrointestinal tract but information on this point is lacking. Mannose and fucose are found in a great variety of glycoproteins.

 

SALES SPECIFICATION

APPEARANCE

white crystalline powder

PURITY 

99.0% min (sum of enantiomers, HPLC)

MELTING POINT

132 ~ 134 C

LOSS ON DRYING

0.2% max

RESIDUE ON IGNITION

0.1% max

HEAVY METALS

10ppm max

SPECIFIC ROTATION

+13.0° ~ +14.5° (c=10 in H2O)

 

TRANSPORT & REGULATORY INFORMATION

UN NO.

Not regulated

HAZARD SYMBOL

  
PACKING GROUP  

 

SAFETY INFORMATION

HAZARD OVERVIEW

May cause eye and skin irritation. May cause respiratory and digestive tract irritation. Target Organs:Not known

GHS

  

SIGNAL WORD

Not classified

PICTOGRAMS

 

HAZARD STATEMENTS

None

P STATEMENTS

None

EC DIRECTIVES

 

HAZARD CODES

 

RISK PHRASES

  

SAFETY PHRASES

 24/25