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DIGITONIN |
| Synonyms. Digitonin; Digitin; beta-D-Galactopyranoside, (2alpha,3beta,5alpha,15beta,25R)-2,15- dihydroxyspirostan-3-yl O-beta-D-glucopyranosyl-(1->3)-O-beta -D-galactopyranosyl-(1->2)-O- (beta-D-xylopyranosyl- (1->3))-O-beta-D-glucopyranosyl-(1->4)-; beta-D-Galactopyranoside, (2alpha,3beta,5alpha, 15beta,25R)-2,15- dihydroxyspirostan-3-yl O-beta-D- glucopyranosyl- (1.fwdarw.3)-O-beta-D-galactopyranosyl- (1.fwdarw.2)-O-(beta-D-xylopyranosyl-(1.fwdarw.3))- O-beta-D-glucopyranosyl-(1.fwdarw.4)-; |
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| PRODUCT IDENTIFICATION | |
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CAS RN |
11024-24-1 |
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EINECS RN |
234-255-6 |
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FORMULA |
C56H92O29 |
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MOLE WEIGHT |
1229.31 |
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H.S CODE |
2938.90.0000 |
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SMILES |
C1[C@@]2([C@@H]3[C@@H](O[C@@]4([C@H]3C)CC[C@@H](C)CO4)[C@H] ([C@H]2 [C@H]2[C@H]([C@@]3([C@H](C[C@@H](O[C@@H]4O [C@@ H]([ C@H](O[C@H]5[C@@H]([C@@H](O[C@H]6[C@@H]([C@H]([ C@H](O )CO6) O)O)[C@@H](O)[C@H](O5)CO)O[C@H]5 [C@@H ]([C@@H](O [C@@H]6O[C @@H]([C@@H](O)[C@@H]([C@H]6O) O)CO)[C@ @H](O)[C@H](O5 )CO)O )[ C @ @H]([C@H]4O)O)C O)[C@@ H](C3)O)CC2)C)C1)O)C |
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CLASSIFICATION |
Glycoside, Steroid, Saponin |
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EXTRA NOTES |
A glycoside obtained from Digitalis purpurea; the aglycone is digitogenin which is bound to five sugars. Digitonin solubilizes lipids, especially in membranes and is used as a tool in cellular biochemistry, and reagent for precipitating cholesterol. It has no cardiac effects MeSH |
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| PHYSICAL AND CHEMICAL PROPERTIES | |
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PHYSICAL STATE |
white to off-white crystalline powder |
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MELTING POINT |
230 ~ 240 C |
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BOILING POINT |
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DENSITY |
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SOLUBILITY IN WATER |
10 g/l |
| SOLVENT SOLUBILITY |
Practically insol in chloroform, ether. |
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VAPOR DENSITY |
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log P(octanol-water) |
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VAPOR PRESSURE |
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AUTOIGNITION TEMP |
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| pK |
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REFRACTIVE INDEX |
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FLASH POINT |
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| STABILITY AND REACTIVITY | |
| STABILITY | Stable under normal conditions. |
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INCOMPATIBLE MATERIALS |
Strong oxidizing agents. |
| POLYMERIZATION |
Has not been reported |
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NFPA RATINGS |
Health: 2, Flammability: 0, Reactivity: 0 |
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| EXTERNAL LINKS & GENERAL DESCRIPTION |
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USA.gov - Digitonin Wikipedia Linking - Digitonin Google Scholar Search - Digitonin U.S. National Library of Medicine - Digitonin PubChem Compound Summary - Digitonin KEGG (Kyoto Encyclopedia of Genes and Genomes) - Digitonin ChEBI (http://www.ebi.ac.uk/chebi/) - Digitonin NCBI (http://www.ncbi.nlm.nih.gov/) - Digitonin Material Safety Data Sheet - Digitonin EPA - Substance Registry Services - Digitonin |
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| SALES SPECIFICATION | |
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APPEARANCE |
white to off-white crystalline powder |
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ASSAY |
95% min |
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MELTING POINT |
230 ~ 240 C |
| OPTICAL ROTATION |
-53° ~ -55° (c=2.8, mEoh) |
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HEAVY METALS |
10ppm max |
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| TRANSPORT & REGULATORY INFORMATION | |
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UN NO. |
3462 |
| HAZARD CLASS |
6.1 |
| PACKING GROUP | III |
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| SAFETY INFORMATION | |
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HAZARD OVERVIEW |
GHS (Globally Harmonised System) Classification: Acute toxicity (Oral). Acute toxicity (Dermal). Acute toxicity (Inhalation). Hazard statement(s): Toxic if swallowed or in contact with skin, Fatal if inhaled. |
| SIGNAL WORD | Danger |
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PICTOGRAMS |
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HAZARD STATEMENTS |
H301-H311-H330 |
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P STATEMENTS |
P260-P280-P284-P310 |
| EC DIRECTIVES |
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| HAZARD CODES |
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RISK PHRASES |
23/24/25 |
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SAFETY PHRASES |
22-28-36/37-45 |
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| PACKING |
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Preserved in light-resistant and well-closed bottles |
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