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LAPACHOL |
| Synonyms. Lapachol; 2-Hydroxy-3-(3-methylbut-2-enyl)-1,4-naphthoquinone; 2-Hydroxy-3-(3-methyl-2-butenyl)-1,4-naphthalenedione; Bethabarra wood; C.I. 75490; C.I. Natural Yellow 16; Greenharten; Greenhartin; Lapachic acid; Taiguic acid; Tecomin; Zlut prirodni 16 |
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| PRODUCT IDENTIFICATION | |
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CAS RN |
84-79-7 |
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EINECS RN |
201-563-7 |
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FORMULA |
C15H14O3 |
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MOLE WEIGHT |
242.27 |
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H.S CODE |
2914.69.9000 |
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SMILES |
c12c(C(C(O)=C(C1=O)C\C=C(\C)C)=O)cccc2 |
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CLASSIFICATION |
Antiparasitic agent, Naphthoquinone |
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EXTRA NOTES |
a natural organic compound isolated from the lapacho tree.[3] This tree is known botanically as Handroanthus impetiginosus, but was formerly known by various other botanical names such as Tabebuia avellanedae.[4] Lapachol is also found in other species of Handroanthus. wikipedia |
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| PHYSICAL AND CHEMICAL PROPERTIES | |
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PHYSICAL STATE. |
white to off-white crystalline powder |
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MELTING POINT |
141 ~ 143 C |
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BOILING POINT |
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DENSITY |
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SOLUBILITY IN WATER |
Slightly soluble |
| SOLVENT SOLUBILITY |
Soluble in alcohol, chloroform, benzene, acetic acid. Soluble in aq NaOH solution forming a bright red sodium salt. Slightly soluble in ether |
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VAPOR DENSITY |
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log P(octanol-water) |
3.13 |
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VAPOR PRESSURE |
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AUTOIGNITION TEMP |
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| pK |
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REFRACTIVE INDEX |
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FLASH POINT |
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| STABILITY AND REACTIVITY | |
| STABILITY | Stable under normal conditions. |
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INCOMPATIBLE MATERIALS |
Strong oxidizing agents |
| POLYMERIZATION |
Has not been reported |
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NFPA RATINGS |
Health: 1, Flammability: 0, Reactivity: 0 |
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| EXTERNAL LINKS & GENERAL DESCRIPTION |
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USA.gov - Lapachol Wikipedia Linking - Lapachol Google Scholar Search - Lapachol U.S. National Library of Medicine - Lapachol PubChem Compound Summary - Lapachol KEGG (Kyoto Encyclopedia of Genes and Genomes) - Lapachol NCBI (http://www.ncbi.nlm.nih.gov/) - Lapachol |
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| SALES SPECIFICATION | |
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APPEARANCE |
white to off-white crystalline powder |
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ASSAY |
98% min |
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MELTING POINT |
140 ~ 143 C |
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LOSS ON DRYING |
1% max |
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HEAVY METALS |
20ppm max |
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| TRANSPORT & REGULATORY INFORMATION | |
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UN NO. |
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| HAZARD CLASS |
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| PACKING GROUP | |
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| SAFETY INFORMATION | |
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HAZARD OVERVIEW |
GHS (Globally Harmonised System) Classification: Acute toxicity (Oral), Acute toxicity (Inhalation), Acute toxicity (Dermal), Skin irritation, Eye irritation, Specific target organ toxicity. |
| SIGNAL WORD | Warning |
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PICTOGRAMS |
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HAZARD STATEMENTS |
H302-H312-H315-H319-H335 |
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P STATEMENTS |
P261-P-280-P305 + P351 + P338 |
| EC DIRECTIVES |
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| HAZARD CODES |
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RISK PHRASES |
20/21/22-36/37/38 |
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SAFETY PHRASES |
26-36 |
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| PACKING |
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Preserve in light-resistant and well-closed containers |
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