LITHOCHOLIC ACID

Synonyms. Lithocholic acid; (3-alpha,5-beta)-3-Hydroxycholan-24-oic acid; 17-beta-(1-Methyl-3-carboxypropyl)ethiocholan-3-alpha-ol; 17beta-(1-Methyl-3-carboxypropyl)etiocholan-3alpha-ol; 3-alpha-Hydroxy-5-beta-cholanic acid; 3-alpha-Hydroxycholanic acid; 3-Hydroxycholan-24-oic acid; 3alpha-Hydroxy-5beta-cholan-24-oic acid; 3alpha-Hydroxy-5beta-cholanic acid; 3alpha-Hydroxycholanic acid;

LITHOCHOLIC ACID

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PRODUCT IDENTIFICATION

CAS RN

434-13-9

EINECS RN

207-099-1

FORMULA

C24H40O3

MOLE WEIGHT

376.57

H.S CODE

2918.19.9000

SMILES

C1[C@@]2([C@H](CC[C@H]2[C@@H]2CC[C@H]3[C@@](CC[C@H](O)C3) (C) [C@@H]2C1) [C@@H](CCC(=O)O)C)C

CLASSIFICATION

Bile acid

EXTRA NOTES

A bile acid formed from chenodeoxycholate by bacterial action, usually conjugated with glycine or taurine. It acts as a detergent to solubilize fats for absorption and is itself absorbed. It is used as cholagogue and choleretic.

 

PHYSICAL AND CHEMICAL PROPERTIES

PHYSICAL STATE

white to off-white crystalline powder

MELTING POINT

180 ~ 188 C

BOILING POINT

 

DENSITY

 

SOLUBILITY IN WATER

Insoluble

SOLVENT SOLUBILITY

Slightly soluble in glacial acetic acid. Soluble in ethyl acetate, alcohol

VAPOR DENSITY

 

log P(octanol-water)

6.19

VAPOR PRESSURE

 

AUTOIGNITION TEMP

 
pK

 

REFRACTIVE INDEX

 

FLASH POINT

 

 

STABILITY AND REACTIVITY
STABILITY Stable under normal conditions.

INCOMPATIBLE MATERIALS

Strong oxidizing agents.

POLYMERIZATION

Has not been reported

NFPA RATINGS

Health: 1, Flammability: 0, Reactivity: 0

 

EXTERNAL LINKS & GENERAL DESCRIPTION

USA.gov - Lithocholic acid

Wikipedia Linking - Lithocholic acid

Google Scholar Search - Lithocholic acid

U.S. National Library of Medicine - Lithocholic acid

PubChem Compound Summary - Lithocholic acid

KEGG (Kyoto Encyclopedia of Genes and Genomes) -  Lithocholic acid

ChEBI (http://www.ebi.ac.uk/chebi/) -  Lithocholic acid

NCBI (http://www.ncbi.nlm.nih.gov/) -  Lithocholic acid

Material Safety Data Sheet - Lithocholic acid

Hazardous Substances Data Bank - Lithocholic acid

EPA - Substance Registry Services - Lithocholic acid

 

SALES SPECIFICATION

APPEARANCE

white to off-white crystalline powder

ASSAY

98% min

MELTING POINT

183 ~ 188 C

OPTICAL ROTATION

+32° ~ +36° (c=1.5, EtOH)

LOSS ON DRYING

1% max

HEAVY METALS

10ppm max

 

TRANSPORT & REGULATORY INFORMATION

UN NO.

 

HAZARD CLASS

 

PACKING GROUP  

 

SAFETY INFORMATION

HAZARD OVERVIEW

GHS (Globally Harmonised System) Classification: Acute toxicity (Oral). Hazard statements: Harmful if swallowed.

 

PACKING

Preserved in light-resistant and well-closed bottles