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MADECASSOSIDE |
| Synonyms. Madecassoside; O-6-Deoxy-alpha-L-mannopyranosyl-(1.4)-O-beta- D-glucopyranosyl-(1.6)-beta-D-glucopyranosyl (2alpha,3beta,4alpha,6beta)-2,3,6,23- tetrahydroxyurs-12-en-28-oate; |
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| PRODUCT IDENTIFICATION | |
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CAS RN |
34540-22-2 |
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EINECS RN |
252-076-1 |
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FORMULA |
C48H78O20 |
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MOLE WEIGHT |
975.12 |
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H.S CODE |
2938.90.0000 |
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SMILES |
O1[C@@H](O[C@@H]2[C@@H]([C@@H](O)[C@@H](O[C@@H]2CO)OC [C @@H]2[C@@H] ([C@@H]([C@@H](O)[C@@H](OC([C@@]34CC[C@@]5(C) [C@@] 6(C[C@@H] (O)[C@@H]7[C@@]([C@@H]([C@@H](C[C@@]7( [C@@ H]6CC=C5[C@@H]3 [C@@H]([C@@H](CC4)C)C)C)O)O)(C)CO)C)=O)O2 )O)O)O)[C@@H]([C@@H] ([C@@H]([C@@H]1C)O)O)O |
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CLASSIFICATION |
Phytochemical, Pentacyclic triterpene. |
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EXTRA NOTES |
Biochem/physiol Actions:Madecassoside is a triterpenoid compound found in Centella asiatica (Gotu kola), a medicinal herb used in traditional Chinese medicine (TCM), Ayurvedic medicine, and traditional African medicine. Madecassoside has a wide range of reported biological activities including, anti-inflammatory, wound healing, and anti-oxidant activities. It has been reported to suppress LPS-induced TNF-alpha production via inhibition of ERK, p38, and NF-kappaB activity. (sigmaaldrich) |
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| PHYSICAL AND CHEMICAL PROPERTIES | |
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PHYSICAL STATE. |
white powder |
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MELTING POINT |
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BOILING POINT |
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DENSITY |
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SOLUBILITY IN WATER |
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| SOLVENT SOLUBILITY |
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VAPOR DENSITY |
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log P(octanol-water) |
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VAPOR PRESSURE |
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AUTOIGNITION TEMP |
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REFRACTIVE INDEX |
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FLASH POINT |
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| STABILITY AND REACTIVITY | |
| STABILITY | Stable under normal conditions. |
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INCOMPATIBLE MATERIALS |
Strong oxidizing agents |
| POLYMERIZATION |
Has not been reported |
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NFPA RATINGS |
Health: 1, Flammability: 0, Reactivity: 0 |
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| EXTERNAL LINKS & GENERAL DESCRIPTION |
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USA.gov - Madecassoside Wikipedia Linking - Madecassoside Google Scholar Search - Madecassoside U.S. National Library of Medicine - Madecassoside PubChem Compound Summary - Madecassoside KEGG (Kyoto Encyclopedia of Genes and Genomes) - Madecassoside http://www.ebi.ac.uk/chebi/ - Madecassoside http://www.ncbi.nlm.nih.gov/ - Madecassoside EPA - Substance Registry Services - Madecassoside |
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| SALES SPECIFICATION | |
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APPEARANCE |
white powder |
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ASSAY |
90% min |
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LOSS ON DRYING |
1% max |
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HEAVY METALS |
10ppm max |
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| TRANSPORT & REGULATORY INFORMATION | |
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UN NO. |
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| PACKING GROUP | |
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| SAFETY INFORMATION | |
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HAZARD OVERVIEW |
GHS (Globally Harmonised System) Classification: Not a dangerous substance. Potential Health Effects: Eyes - May cause eye irritation. Skin - May be harmful if absorbed through skin May cause skin irritation. Inhalation - May be harmful if inhaled. May cause respiratory tract irritation. Ingestion - May be harmful if swallowed. |
| HAZARD CODES |
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RISK PHRASES |
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SAFETY PHRASES |
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| PACKING |
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Preserved in light-resistant and well-closed bottles |
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