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PICROTOXININ |
| Synonyms. Picrotoxinin; (1aR-(1aalpha,2abeta,3beta,6beta,6abeta,8aS*,8bbeta,9R*))-Hexahydro- 2a-hydroxy-8b-methyl-9-(1-methylethenyl)-3,6-methano- 8H-1,5,7-trioxa cyclopenta(ij)cycloprop(a) azulene-4,8(3H)-dione; |
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| PRODUCT IDENTIFICATION | |
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CAS RN |
17617-45-7 |
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EINECS RN |
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FORMULA |
C15H16O6 |
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MOLE WEIGHT |
292.28 |
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H.S CODE |
3002.90.5150 |
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SMILES |
C@@]123C(=O)O[C@H]4[C@@]1([C@]([C@H]1C(=O)O[C@@H]4[C@H]1C (=C)C)(C[ C@H]2O3)O)C |
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CLASSIFICATION |
GABA Antagonist |
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EXTRA NOTES |
Toxic component of picrotoxin; noncompetitive antagonist of ionotropic GABA receptors |
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| PHYSICAL AND CHEMICAL PROPERTIES | |
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PHYSICAL STATE |
white to off-white crystalline powder |
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MELTING POINT |
209 ~ 210 C |
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BOILING POINT |
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DENSITY |
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SOLUBILITY IN WATER |
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| SOLVENT SOLUBILITY |
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VAPOR DENSITY |
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log P(octanol-water) |
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VAPOR PRESSURE |
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AUTOIGNITION TEMP |
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| pK |
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REFRACTIVE INDEX |
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FLASH POINT |
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| STABILITY AND REACTIVITY | |
| STABILITY | Stable under normal conditions. |
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INCOMPATIBLE MATERIALS |
Strong oxidizing agents. |
| POLYMERIZATION |
Has not been reported |
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NFPA RATINGS |
Health: 3, Flammability: 0, Reactivity: 0 |
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| EXTERNAL LINKS & GENERAL DESCRIPTION |
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USA.gov - Picrotoxinin Wikipedia Linking - Picrotoxinin Google Scholar Search - Picrotoxinin U.S. National Library of Medicine - Picrotoxinin PubChem Compound Summary - Picrotoxinin KEGG (Kyoto Encyclopedia of Genes and Genomes) - Picrotoxinin NCBI (http://www.ncbi.nlm.nih.gov/) - Picrotoxinin EPA - Substance Registry Services - Picrotoxinin |
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| SALES SPECIFICATION | |
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APPEARANCE |
white to off-white crystalline powder |
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ASSAY |
98% min |
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MELTING POINT |
209 ~ 210 C |
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LOSS ON DRYING |
1% max |
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| TRANSPORT & REGULATORY INFORMATION | |
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UN NO. |
2811 |
| HAZARD CLASS |
6.0 |
| PACKING GROUP | II |
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| SAFETY INFORMATION | |
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HAZARD OVERVIEW |
GHS (Globally Harmonised System) Classification: Acute toxicity (Oral). Hazard statements: Fatal if swallowed. |
| SIGNAL WORD | Danger |
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PICTOGRAMS |
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HAZARD STATEMENTS |
H300 |
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P STATEMENTS |
P264-P301 + P310 |
| EC DIRECTIVES |
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| HAZARD CODES |
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RISK PHRASES |
28 |
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SAFETY PHRASES |
28-36/37-45 |
T+|
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| PACKING |
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Preserved in light-resistant and well-closed bottles |
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