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PODOPHYLLUM |
| Synonyms. Podophyllum; Podophyllin; Podophyllum resin; Podophyllin; Podofillina; |
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| PRODUCT IDENTIFICATION | |
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CAS RN |
9000-55-9 |
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EINECS RN |
232-546-2 |
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FORMULA |
C88H92O34 |
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MOLE WEIGHT |
1693.65 |
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H.S CODE |
2939.90.0000 |
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SMILES |
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CLASSIFICATION |
Keratolytic agent |
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EXTRA NOTES |
Caustic extract from the roots of Podophyllum peltatum and P. emodi. It contains PODOPHYLLOTOXIN and its congeners and is very irritating to mucous membranes and skin. Podophyllin is a violent purgative that may cause CNS damage and teratogenesis. It is used as a paint for warts, skin neoplasms, and senile keratoses. MeSH |
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| PHYSICAL AND CHEMICAL PROPERTIES | |
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PHYSICAL STATE. |
brown powder |
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MELTING POINT |
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BOILING POINT |
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DENSITY |
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SOLUBILITY IN WATER |
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| SOLVENT SOLUBILITY |
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VAPOR DENSITY |
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log P(octanol-water) |
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VAPOR PRESSURE |
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AUTOIGNITION TEMP |
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| pK |
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REFRACTIVE INDEX |
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FLASH POINT |
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| STABILITY AND REACTIVITY | |
| STABILITY | Stable under normal conditions. |
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INCOMPATIBLE MATERIALS |
Oxidizing agents |
| POLYMERIZATION |
Has not been reported |
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NFPA RATINGS |
Health: 4, Flammability: 0, Reactivity: 0 |
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| EXTERNAL LINKS & GENERAL DESCRIPTION |
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USA.gov - Podophyllum Google Scholar Search - Podophyllum U.S. National Library of Medicine - Podophyllum PubChem Compound Summary - Podophyllum KEGG (Kyoto Encyclopedia of Genes and Genomes) - Podophyllum ChEBI (http://www.ebi.ac.uk/chebi/) - Podophyllum NCBI (http://www.ncbi.nlm.nih.gov/) - Podophyllum Material Safety Data Sheet - Podophyllum Human Metabolome Database - Podophyllum Hazardous Substances Data Bank - Podophyllum EPA - Substance Registry Services - Podophyllum |
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| SALES SPECIFICATION | |
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APPEARANCE |
brown powder |
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ASSAY |
50% min |
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| TRANSPORT & REGULATORY INFORMATION | |
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UN NO. |
2811 |
| HAZARD CLASS |
6.1 |
| PACKING GROUP | II |
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| SAFETY INFORMATION | |
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HAZARD OVERVIEW |
GHS (Globally Harmonised System) Classification: Acute toxicity (Inhalation). Acute toxicity (Dermal). Acute toxicity (Oral). Skin corrosion. Serious eye damage. Reproductive toxicity. Hazard statements: Fatal if swallowed or in contact with skin. Causes severe skin burns and eye damage. Fatal if inhaled. May damage fertility or the unborn child. |
| SIGNAL WORD | Danger |
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PICTOGRAMS |
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HAZARD STATEMENTS |
H300+H310-H314-H330-H360 |
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P STATEMENTS |
P201-P260-P264-P280-P284-P302 + P350 |
| EC DIRECTIVES |
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| HAZARD CODES |
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RISK PHRASES |
61-26/27/28-34 |
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SAFETY PHRASES |
53-26-27-36/37/39-45 |
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| PACKING |
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Preserve in light-resistant and well-closed containers |
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