PODOPHYLLUM

Synonyms. Podophyllum; Podophyllin; Podophyllum resin; Podophyllin; Podofillina;

 

 

PRODUCT IDENTIFICATION

CAS RN

9000-55-9

EINECS RN

232-546-2

FORMULA

C88H92O34

MOLE WEIGHT

1693.65

H.S CODE

2939.90.0000

SMILES

 

CLASSIFICATION

Keratolytic agent

EXTRA NOTES

Caustic extract from the roots of Podophyllum peltatum and P. emodi. It contains PODOPHYLLOTOXIN and its congeners and is very irritating to mucous membranes and skin. Podophyllin is a violent purgative that may cause CNS damage and teratogenesis. It is used as a paint for warts, skin neoplasms, and senile keratoses. MeSH
Other RN: 8050-60-0, 8061-07-2, 8063-20-5

 

PHYSICAL AND CHEMICAL PROPERTIES

PHYSICAL STATE.

brown powder

MELTING POINT

 

BOILING POINT

 

DENSITY

 

SOLUBILITY IN WATER

 

SOLVENT SOLUBILITY

 

VAPOR DENSITY

 

log P(octanol-water)

 

VAPOR PRESSURE

 

AUTOIGNITION TEMP

 
pK

 

REFRACTIVE INDEX

 

FLASH POINT

 

 

STABILITY AND REACTIVITY
STABILITY Stable under normal conditions.

INCOMPATIBLE MATERIALS

Oxidizing agents

POLYMERIZATION

Has not been reported

NFPA RATINGS

Health: 4, Flammability: 0, Reactivity: 0

 

EXTERNAL LINKS & GENERAL DESCRIPTION

USA.gov - Podophyllum

Google Scholar Search - Podophyllum

U.S. National Library of Medicine - Podophyllum

PubChem Compound Summary - Podophyllum

KEGG (Kyoto Encyclopedia of Genes and Genomes) -  Podophyllum

ChEBI (http://www.ebi.ac.uk/chebi/) -  Podophyllum

NCBI (http://www.ncbi.nlm.nih.gov/) -  Podophyllum

Material Safety Data Sheet - Podophyllum

Human Metabolome Database - Podophyllum

Hazardous Substances Data Bank - Podophyllum

EPA - Substance Registry Services - Podophyllum

 

SALES SPECIFICATION

APPEARANCE

brown powder

ASSAY

50% min

 

TRANSPORT & REGULATORY INFORMATION

UN NO.

2811

HAZARD CLASS

6.1

PACKING GROUP II

 

SAFETY INFORMATION

HAZARD OVERVIEW

GHS (Globally Harmonised System) Classification: Acute toxicity (Inhalation). Acute toxicity (Dermal). Acute toxicity (Oral). Skin corrosion. Serious eye damage. Reproductive toxicity. Hazard statements: Fatal if swallowed or in contact with skin. Causes severe skin burns and eye damage. Fatal if inhaled. May damage fertility or the unborn child.

SIGNAL WORD Danger

PICTOGRAMS

HAZARD STATEMENTS

H300+H310-H314-H330-H360

P STATEMENTS

P201-P260-P264-P280-P284-P302 + P350

EC DIRECTIVES

 

HAZARD CODES

RISK PHRASES

61-26/27/28-34

SAFETY PHRASES

53-26-27-36/37/39-45

 

PACKING

Preserve in light-resistant and well-closed containers