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PROFLAVINE |
| Synonyms. Proflavine; 3,6-Acridinediamine; 2,8-Diaminoacridine; 2,8-Diaminoacridinium; 3,6-Diaminoacridine; 3,6-Diaminoacridinium; 3,7-Diamino-5-azaanthracene; Isoflav base; Proflavin; Proflavina; Proflavinum; Acridine-3,6-diamine; |
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| PRODUCT IDENTIFICATION | |
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CAS RN |
92-62-6 |
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EINECS RN |
202-172-4 |
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FORMULA |
C13H11N3 |
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MOLE WEIGHT |
209.25 |
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H.S CODE |
2933.99.7900 |
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SMILES |
c12c(nc3cc(N)ccc3c1)cc(N)cc2 |
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CLASSIFICATION |
Antiseptic, Acridine |
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EXTRA NOTES |
An aminoacridine that is acridine that is substituted by amino groups at positions 3 and 6. A slow-acting bacteriostat that is effective against many Gram-positive bacteria (but ineffective against spores), its salts were formerly used for treatment of burns and infected wounds. [ChEBI] |
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| PHYSICAL AND CHEMICAL PROPERTIES | |
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PHYSICAL STATE. |
beige to brown powder |
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MELTING POINT |
285 C |
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BOILING POINT |
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DENSITY |
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SOLUBILITY IN WATER |
Soluble |
| SOLVENT SOLUBILITY |
Soluble in ethanol. Insoluble in benzene, ether. |
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VAPOR DENSITY |
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log P(octanol-water) |
1.83 |
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VAPOR PRESSURE |
8.94E-08 mm Hg |
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AUTOIGNITION TEMP |
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| pK |
8.75 |
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REFRACTIVE INDEX |
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FLASH POINT |
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| STABILITY AND REACTIVITY | |
| STABILITY | Stable under normal conditions. |
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INCOMPATIBLE MATERIALS |
Strong oxidizing agents |
| POLYMERIZATION |
Has not been reported |
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NFPA RATINGS |
Health: 1, Flammability: 0, Reactivity: 0 |
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| EXTERNAL LINKS & GENERAL DESCRIPTION |
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USA.gov - Proflavine Wikipedia Linking - Proflavine Google Scholar Search - Proflavine U.S. National Library of Medicine - Proflavine PubChem Compound Summary - Proflavine Drug Bank - Proflavine KEGG (Kyoto Encyclopedia of Genes and Genomes) - Proflavine http://www.ebi.ac.uk/chebi/ - Proflavine http://www.ncbi.nlm.nih.gov/ - Proflavine Hazardous Substances Data Bank - Proflavine EPA - Substance Registry Services - Proflavine |
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| SALES SPECIFICATION | |
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APPEARANCE |
beige to brown powder |
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ASSAY |
98% min |
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pH |
7 ~ 9 |
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LOSS ON DRYING |
6.5% max |
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ASH |
0.5% max |
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| TRANSPORT & REGULATORY INFORMATION | |
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UN NO. |
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| HAZARD CLASS |
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| PACKING GROUP | |
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| SAFETY INFORMATION | |
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HAZARD OVERVIEW |
GHS (Globally Harmonised System) Classification: Eye irritation. Hazard statements: Causes eye irritation. Potential Health Effects: Eyes - May cause eye irritation. Skin May - be harmful if absorbed through skin. May cause skin irritation. Ingestion - May be harmful if swallowed. Inhalation - May be harmful if inhaled. May cause respiratory tract irritation. |
| SIGNAL WORD | Warning |
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PICTOGRAMS |
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HAZARD STATEMENTS |
H319 |
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P STATEMENTS |
P305 + P351 + P338 |
| EC DIRECTIVES |
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| HAZARD CODES |
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RISK PHRASES |
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SAFETY PHRASES |
26-36 |
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| PACKING |
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Preserved in light-resistant and well-closed bottles |
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