|
SALSOLINOL |
| Synonyms. Salsolinol; (R,S)-Salsolinol; 1-Methyl-6,7-dihydroxy-1,2,3,4-tetrahydroisoquinoline; 1,2,3,4-Tetrahydro-1-methylisoquinoline-6,7-diol; 1-Methyl-1,2,3,4-tetrahydroisoquinoline-6,7-diol; |
|
|
| PRODUCT IDENTIFICATION | |
|
CAS RN |
525-72-4 (free base) |
|
EINECS RN |
|
|
FORMULA |
C10H13NO2 |
|
MOLE WEIGHT |
179.22 |
|
H.S CODE |
2933.49.6000 |
|
SMILES |
CC1C2=CC(=C(C=C2CCN1)O)O |
|
CLASSIFICATION |
|
|
EXTRA NOTES |
Other RN: 78579-88-1 |
|
|
| PHYSICAL AND CHEMICAL PROPERTIES (HBr) | |
|
PHYSICAL STATE. |
white to yellow powder |
|
MELTING POINT |
186 ~ 187 C |
|
BOILING POINT |
|
|
DENSITY |
|
|
SOLUBILITY IN WATER |
|
| SOLVENT SOLUBILITY |
|
|
VAPOR DENSITY |
|
|
log P(octanol-water) |
|
|
VAPOR PRESSURE |
|
|
AUTOIGNITION TEMP |
|
| pK |
|
|
REFRACTIVE INDEX |
|
|
FLASH POINT |
|
|
|
| STABILITY AND REACTIVITY | |
| STABILITY | Stable under normal conditions. |
|
INCOMPATIBLE MATERIALS |
Strong oxidizing agents, Strong acids, Acid chlorides, Acid anhydrides |
| POLYMERIZATION |
Has not been reported |
|
NFPA RATINGS |
Health: 2, Flammability: 0, Reactivity: 0 |
|
|
| EXTERNAL LINKS & GENERAL DESCRIPTION |
|
USA.gov - Salsolinol Google Scholar Search - Salsolinol U.S. National Library of Medicine - Salsolinol PubChem Compound Summary - Salsolinol KEGG (Kyoto Encyclopedia of Genes and Genomes) - Salsolinol NCBI (http://www.ncbi.nlm.nih.gov/) - Salsolinol Human Metabolome Database - Salsolinol Biochem/physiol Actions:Salsolinol is the condensation product of acetaldehyde and dopamine. Salsolinol is a potential neurotoxin suspected to contribute to alcohol abuse. It appears that salsolinol excites the ventral tegmental area (VTA) dopamine neurons indirectly by activating μ-opioid receptors (MORs), which inhibit GABA neurons in the VTA. sigmaaldrich |
|
|
| SALES SPECIFICATION (HBr) | |
|
APPEARANCE |
white to yellow powder |
|
ASSAY |
98% min |
|
MELTING POINT |
186 ~ 187 C |
|
LOSS ON DRYING |
1% max |
|
|
| TRANSPORT & REGULATORY INFORMATION | |
|
UN NO. |
|
| HAZARD CLASS |
|
| PACKING GROUP | |
|
|
| SAFETY INFORMATION (HBr) | |
|
HAZARD OVERVIEW |
GHS (Globally Harmonised System) Classification: Acute toxicity (Oral). Skin irritation. Eye irritation. Specific target organ toxicity - single exposure. Hazard statements: Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation. |
| SIGNAL WORD | Warning |
|
PICTOGRAMS |
|
|
HAZARD STATEMENTS |
H315-H319-H335 |
|
P STATEMENTS |
P261-P305 + P351 + P338 |
| EC DIRECTIVES |
|
| HAZARD CODES |
|
|
RISK PHRASES |
36/37/38 |
|
SAFETY PHRASES |
26-36 |
|
|
| PACKING |
|
Preserve in light-resistant and well-closed containers |
|
|