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SANTONIN |
| Synonyms. Santonin; alpha-santonin; (-)-Santonine; (3S)-2,3,3a,4,5,5a,8,9bbeta-Octahydro-3,5abeta, 9-trimethylnaphtho(1,2-b)furan-2,8-dion; 11-Epiisoeusantona-1,4-dienic acid, 6alpha-hydroxy-3-oxo-, gamma-lactone; (-)-L-alpha-Santonin; L-alpha-Santonin; 3a,5,5a,9b-Tetrahydro-3,5a,9-trimethyl naphtho (1,2-b)puran-2,8(3H,4H)-dione; Santoninic anhydride; Santoninum; Semenen; |
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| PRODUCT IDENTIFICATION | |
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CAS RN |
481-06-1 |
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EINECS RN |
207-560-7 |
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FORMULA |
C15H18O3 |
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MOLE WEIGHT |
246.30 |
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H.S CODE |
2932.20.5050 |
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SMILES |
C1=2[C@@H]3[C@@H](CC[C@@]1(C=CC(C2C)=O)C)[C@H](C)C(O3)=O |
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CLASSIFICATION |
Anti-Infective agent, Sesquiterpene lactone, Naphthofuran |
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EXTRA NOTES |
Other RN: 881738-49-4 |
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| PHYSICAL AND CHEMICAL PROPERTIES | |
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PHYSICAL STATE |
white to off-white crystalline powder |
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MELTING POINT |
175 C |
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BOILING POINT |
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DENSITY |
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SOLUBILITY IN WATER |
200 mg/l |
| SOLVENT SOLUBILITY |
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VAPOR DENSITY |
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log P(octanol-water) |
1.78 |
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VAPOR PRESSURE |
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AUTOIGNITION TEMP |
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| pK |
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REFRACTIVE INDEX |
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FLASH POINT |
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| STABILITY AND REACTIVITY | |
| STABILITY | Stable under normal conditions. |
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INCOMPATIBLE MATERIALS |
Strong oxidizing agents. |
| POLYMERIZATION |
Has not been reported |
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NFPA RATINGS |
Health: 1, Flammability: 1, Reactivity: 0 |
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| EXTERNAL LINKS & GENERAL DESCRIPTION |
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USA.gov - Santonin Wikipedia Linking - Santonin Google Scholar Search - Santonin U.S. National Library of Medicine - Santonin PubChem Compound Summary - Santonin KEGG (Kyoto Encyclopedia of Genes and Genomes) - Santonin ChEBI (http://www.ebi.ac.uk/chebi/) - Santonin NCBI (http://www.ncbi.nlm.nih.gov/) - Santonin Material Safety Data Sheet - Santonin Human Metabolome Database - Santonin Hazardous Substances Data Bank - Santonin EPA - Substance Registry Services - Santonin |
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| SALES SPECIFICATION | |
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APPEARANCE |
white to off-white crystalline powder |
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ASSAY |
98% min |
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MELTING POINT |
172 ~ 175 C |
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LOSS ON DRYING |
1% max |
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HEAVY METALS |
10ppm max |
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| TRANSPORT & REGULATORY INFORMATION | |
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UN NO. |
2811 |
| HAZARD CLASS |
6.1 |
| PACKING GROUP | II |
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| SAFETY INFORMATION | |
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HAZARD OVERVIEW |
GHS (Globally Harmonised System) Classification: Acute toxicit (Inhalation), Acute toxicity (Dermal), Acute toxicity (Oral), Skin irritation, Eye irritation, Specific target organ toxicity. Hazard statements: Harmful if swallowed. Fatal in contact with skin or if inhaled. Causes skiN irritation. Causes serious eye irritation. May cause respiratory irritation. |
| SIGNAL WORD | Danger |
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PICTOGRAMS |
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HAZARD STATEMENTS |
H302-H310-H315-H319-H330-H335 |
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P STATEMENTS |
P260-P280-P284-P302 + P350-P305 + P351 + P338-P310 |
| EC DIRECTIVES |
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| HAZARD CODES |
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RISK PHRASES |
26-28-36/37/38 |
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SAFETY PHRASES |
26-28-36-37-45 |
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| PACKING |
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Preserved in light-resistant and well-closed bottles |
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