SENECIPHYLLINE

Synonyms. Seneciphylline; (3Z,6R,14aR,14bR)-Ethylidene-3,4,5,6,9,11,13,14,14a,14b- decahydro-6- hydroxy-6-methyl-5-methylene-(1,6)dioxacyclododecino (2,3,4-gh)pyrrolizine-2,7-dione; alpha-Longilobin; 3,19-Didehydro-12-hydroxysenecionan-11,16-dione; Jacodine;

 

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PRODUCT IDENTIFICATION

CAS RN

480-81-9

EINECS RN

201

FORMULA

C18H23NO5

MOLE WEIGHT

333.38

H.S CODE

2939.99.0000

SMILES

C/C=C\1/CC(=C)[C@@](C(=O)OCC2=CCN3[C@H]2[C@@H](CC3)OC1 =O) (C)O

CLASSIFICATION

 

EXTRA NOTES

Overall Carcinogenic Evaluation: Group 3

 

PHYSICAL AND CHEMICAL PROPERTIES

PHYSICAL STATE.

white to off-white crystalline powder

MELTING POINT

217 ~ 218 C

BOILING POINT

 

DENSITY

 

SOLUBILITY IN WATER

 

SOLVENT SOLUBILITY

 

VAPOR DENSITY

 

log P(octanol-water)

-1.88

VAPOR PRESSURE

 

AUTOIGNITION TEMP

 
pK

 

REFRACTIVE INDEX

 

FLASH POINT

 

 

STABILITY AND REACTIVITY
STABILITY Stable under normal conditions.

INCOMPATIBLE MATERIALS

Oxidizing agents

POLYMERIZATION

Has not been reported

NFPA RATINGS

Health: 2, Flammability: 0, Reactivity: 0

 

EXTERNAL LINKS & GENERAL DESCRIPTION

USA.gov - Seneciphylline

Wikipedia Linking - Seneciphylline

Google Scholar Search - Seneciphylline

U.S. National Library of Medicine - Seneciphylline

PubChem Compound Summary - Seneciphylline

KEGG (Kyoto Encyclopedia of Genes and Genomes) -  Seneciphylline

ChEBI (http://www.ebi.ac.uk/chebi/) -  Seneciphylline

NCBI (http://www.ncbi.nlm.nih.gov/) -  Seneciphylline

Material Safety Data Sheet - Seneciphylline

Human Metabolome Database - Seneciphylline

Hazardous Substances Data Bank - Seneciphylline

EPA - Substance Registry Services - Seneciphylline

 

SALES SPECIFICATION

APPEARANCE

white to off-white crystalline powder

ASSAY

98% min

MELTING POINT

217 ~ 218 C

OPTICAL ACTIVITY

-128° (chloroform)

 

TRANSPORT & REGULATORY INFORMATION

UN NO.

1544

HAZARD CLASS

6.1

PACKING GROUP III

 

SAFETY INFORMATION

HAZARD OVERVIEW

GHS (Globally Harmonised System) Classification: Acute toxicity (Oral). Hazard statements: Toxic if swallowed.

SIGNAL WORD Danger

PICTOGRAMS

HAZARD STATEMENTS

H301

P STATEMENTS

P301 + P310

EC DIRECTIVES

 

HAZARD CODES

RISK PHRASES

25

SAFETY PHRASES

45

 

PACKING

Preserve in light-resistant and well-closed containers