|
WOGONIN |
| Synonyms. Wogonin; 5,7-Dihydroxy-8-methoxy-2-phenyl-4H-1-benzopyran-4-one; 5,7-Dihydroxy-8-methoxyflavone; Vogonin; 5,7-Dihydroxy-8-methoxyflavone; Norwogonin 8-methyl ether; |
|
|
| PRODUCT IDENTIFICATION | |
|
CAS RN |
632-85-9 |
|
EINECS RN |
|
|
FORMULA |
C16H12O5 |
|
MOLE WEIGHT |
284.26 |
|
H.S CODE |
2932.99.6100 |
|
SMILES |
c12c(c(c(O)cc2O)OC)oc(c2ccccc2)cc1=O |
|
CLASSIFICATION |
Flavone, Resorcinol |
|
EXTRA NOTES |
A dihydroxy- and monomethoxy-flavone in which the hydroxy groups are positioned at C-5 and C-7 and the methoxy group is at C-8. ChEBI |
|
|
| PHYSICAL AND CHEMICAL PROPERTIES | |
|
PHYSICAL STATE. |
white to off-white crystalline powder |
|
MELTING POINT |
203 ~ 206 C |
|
BOILING POINT |
|
|
DENSITY |
|
|
SOLUBILITY IN WATER |
|
| SOLVENT SOLUBILITY |
|
|
VAPOR DENSITY |
|
|
log P(octanol-water) |
|
|
VAPOR PRESSURE |
|
|
AUTOIGNITION TEMP |
|
| pK |
|
|
REFRACTIVE INDEX |
|
|
FLASH POINT |
|
|
|
| STABILITY AND REACTIVITY | |
| STABILITY | Stable under normal conditions. |
|
INCOMPATIBLE MATERIALS |
Strong oxidizing agents |
| POLYMERIZATION |
Has not been reported |
|
NFPA RATINGS |
Health: 0, Flammability: 0, Reactivity: 0 |
|
|
| EXTERNAL LINKS & GENERAL DESCRIPTION |
|
USA.gov - Wogonin Wikipedia Linking - Wogonin Google Scholar Search - Wogonin PubChem Compound Summary - Wogonin KEGG (Kyoto Encyclopedia of Genes and Genomes) - Wogonin ChEBI (http://www.ebi.ac.uk/chebi/) - Wogonin NCBI (http://www.ncbi.nlm.nih.gov/) - Wogonin Biochem/physiol Actions Wogonin is an anti-inflammatory agent and COX-2 inhibitor, which inhibits the induction of both iNOS and COX-2. Wogonin inhibits COX-2 (IC50 = 46 μM) without affecting COX-1. Wogonin inhibits iNOS induction and thus inhibts activation-induced C6 glial cell death. Specifically, Wogonin inhibits NF-kappaB-mediated iNOS induction. sigmaaldrich |
|
|
| SALES SPECIFICATION | |
|
APPEARANCE |
white to off-white crystalline powder |
|
ASSAY |
98% min |
|
MELTING POINT |
203 ~ 206 C |
|
HEAVY METALS |
20ppm max |
|
|
| TRANSPORT & REGULATORY INFORMATION | |
|
UN NO. |
|
| HAZARD CLASS |
|
| PACKING GROUP | |
|
|
| SAFETY INFORMATION | |
|
HAZARD OVERVIEW |
GHS (Globally Harmonised System) Classification: Not a dangerous substance. |
|
|
| PACKING |
|
Preserve in light-resistant and well-closed containers |
|
|