1,2-HEXANEDIOL

PRODUCT IDENTIFICATION
CAS NO.

6920-22-5

1,2-HEXANEDIOL

EINECS NO. 230-029-6
FORMULA CH3(CH2)3CH(OH)CH2OH
MOL WT. 118.17

H.S. CODE

 2905.39.9000
TOXICITY  
SYNONYMS 1,2-Dihydroxyhexane; 5,6-Dihydroxyhexane; DL-1,2-Hexanediol;
SMILES OC[C@@H](O)CCCC

CLASSIFICATION

Diol

EXTRA NOTES

Other RN: 87760-48-3

PHYSICAL AND CHEMICAL PROPERTIES

PHYSICAL STATE clear to yellowish liquid
MELTING POINT  
BOILING POINT

223 - 2240 C
SPECIFIC GRAVITY 0.951
SOLUBILITY IN WATER  
pH  
VAPOR DENSITY  

AUTOIGNITION

 
pKa  
log Pow N/A(Octanol-water)
VAPOR PRESSURE N/A(mmHg at 25 C)
HENRY'S LAW N/A(atm-m3/mole at 25 C)
OH RATE N/A(Atmospheric)

NFPA RATINGS

  

REFRACTIVE INDEX

1.442 ± 0.008
FLASH POINT  
STABILITY stable under ordinary conditions. Hygroscopic

EXTERNAL LINKS & GENERAL DESCRIPTION

USA.gov - 1,2-Hexanediol

Wikipedia Linking - Diol

Google Scholar Search - 1,2-Hexanediol

Drug Information Portal (U.S. National Library of Medicine) - 1,2-Hexanediol

PubChem Compound Summary - 1,2-Hexanediol

http://www.ncbi.nlm.nih.gov/ -  1,2-Hexanediol

Material Safety Data Sheet - 1,2-Hexanediol

EPA - Substance Registry Services - 1,2-Hexanediol

http://journals.iucr.org/
.......1,2-Hexanediol solutions exhibited a strong attractive diol-diol interaction, a weak diol-diol attraction was found for 1,6-hexanediol and 1,2-pentanediol, and an extremely weak diol-diol attraction was found in 1,5-pentanediol solutions. The general tendencies are the following: aggregation is stronger as the length of the hydrophobic hydrocarbon chain increases and the 1,2-diols exhibit much stronger attraction then the 1,-diols. The temperature dependence of the aggregation is weak for the 1,2-diols but strong for the 1,-diols, indicating in the latter case the hydrophobic character of the interaction.......

Local:
Glycol: any of a class of organic chemicals characterized by having separate two hydroxyl (-OH) groups, contribute to high water solubility, hygroscopicity and reactivity with many organic compounds, on usually linear and aliphatic carbon chain. The general formula is CnH2n(OH)2 or (CH2)n(OH)2. The broadened names include diols, dihydric alcohols, and dihydroxy alcohols. Ethylene glycol, HOCH2CH2OH, is the simplest member of the glycol family. Mono-, di- and triethylene glycols are the first three members of a homologous series of dihydroxy alcohols. Propylene glycol prepared by hydrolysis of propylene oxide and widely used as an ingredient of antifreeze and humectant in cosmetics is 1,2-propanediol indicating the two hydroxyl group position at 1,2, while trimethylene glycol is 1,3-propanediol with two hydroxyl group on the primary carbon atoms.

Diols contribute to high water solubility, hygroscopicity and reactivity with many organic compounds, on usually linear and aliphatic carbon chain. Alcohols are very weak acids as they lose H+ in the hydroxyl group. Alcohols undergoes dehydration reaction which means the elimination of water molecule  replaced by a pi bond between two adjacent carbon atoms to form alkenes under heating in the presence of strong acids like hydrocloric acid or phosphoric acid. Primary and secondary alcohols can be oxidized to aldehydes and ketones respectively. Carboxylic acids are obtained from oxidation of aldehydes. Oxidation in organic chemistry can be considered to be the loss of hydrogen or gain of oxygen and reduction to gain hydrogen or loss of oxygen. Tertiary alcohols do not react to give oxidation products as they have no H attached to the alcohol carbon. Alcohols undergoes important reactions called nucleophilic substitution in which an electron donor replaces a leaving group, generally conjugate bases of strong acids, as a covalent substitute of some atom. One of important reaction of alcohol is condensation. Ethers are formed by the condensation of two alcohols by heating with sulfuric acid; the reaction is one of dehydration. Almost infinite esters are formed through condensation reaction called esterification between carboxylic acid and alcohol, which produces water. Alcohols are important solvents and chemical raw materials. Alcohols are intermediates for the production of target compounds, such as pharmaceuticals, veterinary medicines, plasticizers, surfactants, lubricants, ore floatation agents, pesticides, hydraulic fluids, and detergents.

Hexanediol

CAS RN

 EINECS
1,2-Hexanediol 6920-22-5 230-029-6
1,3-Hexanediol 21531-91-9

 
1,5-Hexanediol 928-40-5 213-171-3
1,6-Hexanediol 629-11-8 211-074-0
2,4-Hexanediol 19780-90-6

 
2,5-Hexanediol 2935-44-6 220-910-3
3,4-Hexanediol 922-17-8 213-073-0
SALES SPECIFICATION

APPEARANCE

clear to yellowish liquid

PURITY

99.0% min

MOISTURE

0.5% max

TRANSPORTATION
PACKING  
HAZARD CLASS  
UN NO.  
SAFETY INFORMATION

HAZARD OVERVIEW

GHS (Globally Harmonised System) Classification: Skin irritation, Eye irritation, Specific target organ toxicity - single exposure. Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.

GHS

 
SIGNAL WORD

Warning

PICTOGRAMS

HAZARD STATEMENTS

H335-H319-H335

P STATEMENTS

P261-P305 + P351 + P338
EC DIRECTIVES

 
HAZARD CODES

RISK PHRASES

36/37/38

SAFETY PHRASES

26-36



PRICE INFORMATION