| CANOGEN BROMIDE | ||
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PRODUCT IDENTIFICATION |
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| CAS NO. | 506-68-3 |
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| EINECS NO. | 208-051-2 | |
| FORMULA | BrCN | |
| MOL WT. | 105.92 | |
|
H.S. CODE |
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| TOXICITY | Oral rat LD50: 25mg/kg | |
| SYNONYMS | Cyanobromide; BrCN; Cyanogen monobromide; | |
| Bromine cyanide; Bromocyan; Bromocyanide; Bromocyanogen; Bromure de cyanogen; | ||
| DERIVATION | ||
|
CLASSIFICATION |
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PHYSICAL AND CHEMICAL PROPERTIES |
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| PHYSICAL STATE | white crystals | |
| MELTING POINT | 50 - 53 C |
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| BOILING POINT | 61 - 62 C (lit) | |
| SPECIFIC GRAVITY | 1.05 - 1.06 | |
| SOLUBILITY IN WATER | Decomposes (freely soluble in alcohol, ether; soluble in benzene, acetonitrile, dichloromethane, ethanol) | |
| pH | ||
| VAPOR DENSITY | ||
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AUTOIGNITION |
400 C | |
|
NFPA RATINGS |
Health: 1; Flammability: 2; Reactivity: 0 | |
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REFRACTIVE INDEX |
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| FLASH POINT | >65 C | |
| STABILITY | Stable under ordinary conditions. Moisture sensitive | |
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GENERAL DESCRIPTION & APPLICATIONS |
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| The term of cyanogen refers to the radical CN- (symbol Cy) or to the molecule that the two cyano groups are bonded together at their carbon atoms (N≡C−C≡N). Cyanogen is an extremely poisonous colorless gas. Cyanogen chloride (NCCl, CAS RN: 506-77-4), canogen bromide (NCBr, CAS RN: 506-68-3) are molecules that one cyano group is replaced with a chlorine and bromine atom respectively. They are useful reagent in organic synthesis especially in the preparation of sulfonyl cyanides and sulfonyl isocyanates as strongly electrophilic cyanogen compound is attacked by the nucleophilic sulfur. Cyanogen bromide is a compound also used in molecular biology. It reacts electrophilically with the pendant hydroxyl groups of proteins and polysaccharides. This reaction is used in forming imidocarbonate and carbamate groups. This also used to digest some proteins and peptides for the production of methionine-free peptides and for peptide mapping in proteomics. It is used as a coupling reagent for phosphoroamidate or pyrophosphate internucleotide bonds in DNA duplexes. | ||
| SALES SPECIFICATION | ||
|
APPEARANCE |
white crystals | |
| ASSAY | 98.5% min | |
|
MELTING POINT |
50 - 53 C |
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| BOILING POINT | 61 - 62 C (lit) | |
| TRANSPORTATION | ||
| PACKING | ||
| HAZARD CLASS | 6.1 (Packing Group: I) | |
| UN NO. | 1889 | |
| OTHER INFORMATION | ||
| Hazard Symbols: T+,N, Risk Phrases: 26/27/28-34-50/53, Safety Phrases: 28-36/37/39-45-60-61 | ||
