PINACOL |
PRODUCT
IDENTIFICATION
|
CAS
NO. |
76-09-5;
52400-10-9 |
|
EINECS
NO. |
200-933-5 |
FORMULA |
HOC(CH3)2C(CH3)2OH |
MOL
WT. |
118.17 |
H.S.
CODE
|
|
TOXICITY |
|
SYNONYMS |
Tetramethylethylene glycol; 2,3-Dimethyl-2,3-dihydroxybutane;
|
2,3-Dimethyl-2,3-butanediol;
meso-2,3-Dimethyl-2,3-butanediol; Pinacone; 2,3-Dihydroxy-2,3-dimethylbutane;
1,1,2,2-Tetramethylethylene glycol; |
DERIVATION |
|
CLASSIFICATION
|
|
PHYSICAL
AND CHEMICAL PROPERTIES
|
PHYSICAL
STATE |
White to off-white crystal |
MELTING
POINT |
40
- 43 C |
BOILING
POINT |
171
- 172
C |
SPECIFIC
GRAVITY |
0.967 |
SOLUBILITY
IN WATER |
soluble in hot water |
pH |
|
VAPOR
DENSITY |
4.1 |
AUTOIGNITION
|
|
NFPA
RATINGS
|
|
REFRACTIVE
INDEX
|
1.4387
- 1.4407 |
FLASH
POINT |
77
C |
STABILITY |
stable
under ordinary conditions. |
GENERAL
DESCRIPTION AND APPLICATIONS
|
Pinacol is a vicinal glycol with general formula RR'C(OH)C(OH)R"R'", where
two adjacent carbon atoms have -OH groups each. The simplest one is
tetramethylethylene glycol, (CH3)2C(OH)C(OH)(CH3)2, when R is methyl group.
Tetramethylethylene glycol is called pinacol itself also. [Pinacolyl alcohol (CAS
RN: 76-09-5) is
not a pinacol but tert-butyl methyl carbinol
which has one -OH]. Tetramethylethylene
glycol is a white solid soluble in hot water, ethanol and ether, insoluble in
cold water; melting point 40 C; boiling point 171 C; specific gravity 0.967
(at 15 C). Pinacol can be prepared by coupling reaction between the carbonyl
groups with a magnesium-mercury amalgam. Acetone is converted to
tetramethylethylene glycol. The pinacol rearrangement is the reaction of
converting a vicinal diol to a ketone (pinacol to pinacolone), migrating an atom
or bond in a reactant molecule to a different site in a reaction molecule.
Pinacolone is the characteric structue molecule, tert-butyl methylketone. It
is used as an intermediate for biologically active products such as antiviral,
antibacterial, antifungal and antituberculous.
Examples
of pinacolyl
molecules
- 1,1-Dibromopinacolone
(CAS
RN: 30263-65-1)
- 1-Bromopinacolone
(CAS
RN: 5469-26-1)
- 1-Monochloropinacoline
(CAS
RN: 13547-70-1
- 2,2,2-Triphenylacetophenone
(CAS
RN: 466-37-5)
- 2,5-Dimethyl-3-hexyne-2,5-diol
(CAS
RN: 142-30-3)
- 3,4-Diethyl-3,4-hexanediol
(CAS
RN: 6931-71-1)
- 5-((2,2-Dimethylpropionyl)methyl)-5-ethylbarbituric acid
(CAS
RN: 69766-59-2)
- 5-((2,2-Dimethylpropionyl)methyl)-5-isopentylbarbituric acid
(CAS
RN: 69766-29-6)
- 5-Allyl-5-((2,2-dimethylpropionyl)methyl)barbituric acid
(CAS
RN: 69766-33-2)
- Benzopinacol
(CAS
RN: 464-72-2)
- Bis(pinacolato)diboron
(CAS
RN: 73183-34-3)
- Boroval
(CAS
RN: 94242-92-9)
- Chlorosoman
(CAS
RN: 7040-57-5)
- Dichloropinacolin
(CAS
RN: 22591-21-5)
- Diethylstilbestrol
pinacolone (CAS
RN: 18922-13-9)
- Dipinacoline glutamate
(CAS
RN: 123729-01-1)
- O-p-Aminophenyl O'-pinacolyl methylphosphonate
(CAS
RN: 52134-57-3)
- Perfluoropinacol
(CAS
RN: 918-21-8)
- Pinacol
(CAS
RN: 76-09-5)
- Pinacol monoformate
(CAS
RN: 65184-58-9)
- Pinacolone
(CAS
RN: 75-97-8)
- Pinacolyl
dimethylphosphinate (CAS
RN: 92411-69-3)
- Pinacolyl
S-(2-dimethylaminoethyl)methylphosphonothioate (CAS
RN: 34388-36-8)
- Pinacolyl
S-(2-trimethylaminoethyl)methylphosphonothioate (CAS
RN: 38770-03-5)
- Pinacolyl methylphosphonic
acid (CAS
RN: 616-52-4)
- Poly(dimethyldichlorosilane, benzpinacol)
(CAS
RN: 70624-20-3)
- Rhodanpinacolin
(CAS
RN: 26094-11-1)
- Soman (CAS
RN: 96-64-0)
|
SALES
SPECIFICATION |
APPEARANCE
|
White to off-white crystal |
PURITY
|
99.0%
min
|
MOISTURE
|
0.5%
max
|
TRANSPORTATION
|
PACKING |
|
HAZARD
CLASS |
|
UN
NO. |
|
OTHER
INFORMATION |
Hazard Symbols: XI, Risk Phrases: 38,
Safety Phrases: 24/25-37 |
|