TIOXOLONE

Synonyms. Tioxolone; 6-Hydro-2-oxo-1,3-benzoxathiole; 6-Hydroxy-1,3-benzoxathiol-2-one; Thioxolone; Tioxolona; Tioxolonum; Thidoxol; Thioxolon ; Thioxolone; Tioxolon;

TIOXOLONE

Click for original image

 

PRODUCT IDENTIFICATION

CAS RN

4991-65-5

EINECS RN

225-653-0

FORMULA

C7H4O3S

MOLE WEIGHT

168.17

H.S CODE

2934.99.3900

SMILES

c1(ccc2sc(oc2c1)=O)O

CLASSIFICATION

Antiseborrheic agent, Antiacne, Dermatologic

EXTRA NOTES

ATC code: D10AB03

 

PHYSICAL AND CHEMICAL PROPERTIES

PHYSICAL STATE.

white to pale yellow crystalline powder

MELTING POINT

158 ~ 160 C

BOILING POINT

 

DENSITY

 

SOLUBILITY IN WATER

 

SOLVENT SOLUBILITY

 

VAPOR DENSITY

 

log P(octanol-water)

1.67

VAPOR PRESSURE

 

AUTOIGNITION TEMP

 
pK

 

REFRACTIVE INDEX

 

FLASH POINT

 

 

STABILITY AND REACTIVITY
STABILITY Stable under normal conditions.

INCOMPATIBLE MATERIALS

Strong oxidizing agents, Strong bases

POLYMERIZATION

Has not been reported

NFPA RATINGS

Health: 21 Flammability: 0, Reactivity: 0

 

EXTERNAL LINKS & GENERAL DESCRIPTION

USA.gov - Tioxolone

Wikipedia Linking - Tioxolone

Google Scholar Search - Tioxolone

Drug Information Portal (U.S. National Library of Medicine) - Tioxolone

PubChem Compound Summary - Tioxolone

Drug Bank -  Tioxolone

KEGG (Kyoto Encyclopedia of Genes and Genomes) -  Tioxolone

http://www.ebi.ac.uk/chebi/ -  Tioxolone

http://www.ncbi.nlm.nih.gov/ -  Tioxolone

Material Safety Data Sheet - Tioxolone

 

SALES SPECIFICATION

APPEARANCE

white to pale yellow crystalline powder

ASSAY

99% min

MELTING POINT

155 ~ 160 C

WATER

1.0% max

 

TRANSPORT & REGULATORY INFORMATION

UN NO.

 

HAZARD CLASS

 

PACKING GROUP  

 

SAFETY INFORMATION

HAZARD OVERVIEW

OSHA Hazards:Harmful by ingestion., Irritant. GHS (Globally Harmonised System) Classification: Acute toxicity Oral, Skin irritation, Eye irritation, Specific target organ toxicity - single exposure. Harmful if swallowed. Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.

SIGNAL WORD Warning

PICTOGRAMS

PICTOGRAM_GHS07_exclamation.jpg

HAZARD STATEMENTS

H302-H315-H319-H335

P STATEMENTS

P261-P305 + P351 + P338

EC DIRECTIVES

 

HAZARD CODES

CODE_Xn_Xi_harmful_Irritant.gif

RISK PHRASES

22-36/37/38

SAFETY PHRASES

26

 

PACKING

Preserve in light-resistant and well-closed containers