1,2,3,4-TETRAHYDROQUINOLINE

PRODUCT IDENTIFICATION

CAS NO. 635-46-1

1,2,3,4-TETRAHYDROQUINOLINE

EINECS NO. 211-237-6
FORMULA C9H11N
MOL WT. 133.19
H.S. CODE  

TOXICITY

 
SYNONYMS 1,2,3,4-tetrahidroquinolina; 1,2,3,4-tétrahydroquinoléine;
1,2,3,4-Tetrahydrochinolin; Kusol; Tetrahydroquinoline; 1-Azatetralin;
SMILES  

CLASSIFICATION

 

PHYSICAL AND CHEMICAL PROPERTIES

PHYSICAL STATE clear to yellow  liquid
MELTING POINT 10 - 15 C
BOILING POINT 249 C
SPECIFIC GRAVITY 1.06 - 1.07
SOLUBILITY IN WATER 989 (mmg/l)

SOLVENT SOLUBILITY

1 (g/l)
pKa 4.27 ( at 20 C)
log P 2.29 (Octanol-water)
VAPOR PRESSURE 0.048 ( mmHg)
HENRY'S LAW 2.70E-08 (atm-m3/mole at 25 C)
OH RATE 6.52E-11  at 25 C (Atmospheric)
NFPA RATINGS Health: 1; Flammability: 0; Reactivity: 0

REFRACTIVE INDEX

1.593
FLASH POINT

100 C

STABILITY Stable under ordinary conditions.

GENERAL DESCRIPTION & APPLICATIONS

Quinoline, 1-azanaphthalene, is an aromatic nitrogen compound characterized by a solid-ring structure contains a benzene fused to pyridine at two adjacent carbon atoms. (Pyridine is a ring structure compound of five carbon atoms with a nitrogen atom). Quinoline itself is the simplest member of the quinoline. It is a hygroscopic, yellowish oily liquid; slightly soluble in water, soluble alcohol, ether, carbon disulfide and readily in many organic solvents. It can be obtained by the distillation of coal tar. Quinoline can be prepared from aniline with acrolein under heated sulfuric acid (Skraup synthesis). Various quinoline compounds can be prepared by Skraup synthesis series of different oxidizing agents. Isoquinoline differs from quinoline in nitrogen position (at 2). Quinoline family compounds are widely used as a parent compound to make drugs (especially anti-malarial medicines), fungicides, biocides, alkaloids, dyes, rubber chemicals and flavoring agents. They have antiseptic, antipyretic, and antiperiodic properties. They are also used as catalyst, corrosion inhibitor, preservative, and as solvent for resins and terpenes. They are used in transition-metal complex catalyst chemistry for uniform polymerization and luminescence chemistry. They are used as antifoaming agent in refinery field. Quinaldine, 2-methylquinoline, is used as an anti-malaria and preparing other anti-malaria drugs. It is used in manufacturing oil soluble dyes, food colorants, pharmaceuticals, pH indicators and other organic compounds. Quinaldic Acid is a carboxylic acid substituted quinoline at 2 position, a catabolite of tryptophan (aromatic side chain amino acid). Quinazoline, diazanaphthalene at 1,3 positions, is used as a chemical intermediate for making medicines and other organic compounds. It is a fundamental structure in some antihypertensive agents such as prazosin and doxazosin which are peripheral vasodilator. Quinoxaline, diazanaphthalene at 1,4 positions, is used as a chemical intermediate for making fungicides and other organic compounds.
SALES SPECIFICATION

APPEARANCE

clear to yellow liquid
ASSAY

98% min (GC)

TRANSPORTATION
PACKING  
HAZARD CLASS  
UN NO.  
OTHER INFORMATION
Hazard Symbols: XI, Risk Phrases: 36/37/38, Safety Phrases: 26-36/37
TETRAHYDROQUINOLINE MOLECULES

Product

CAS RN

6-Methyl-1,2,3,4-tetrahydroquinoline 91-61-2

6-Methoxy-1,2,3,4-tetrahydroquinoline

120-15-0

Kynurenine Yellow 492-26-2
Hydrocarbostyril 553-03-7
1,2,3,4-Tetrahydroquinoline 635-46-1
1-Methyl-6-(2-(4-quinolinyl)vinyl)-1,2,3,4-tetrahydroquinoline 1586-53-4
2-Methyl-1,2,3,4-tetrahydroquinoline 1780-19-4
1-Amino-1,2,3,4-tetrahydroquinoline 5825-45-6
1-Phenyl-4-amino-1,2,3,4-tetrahydroquinoline 10257-98-4
5,6,7,8-Tetrahydroquinoline 10500-57-9
1-Cinnamoyl-1,2,3,4-tetrahydroquinoline 13262-31-2
Desoxyoxamniquine 21738-41-0
Oxamniquine 21738-42-1
1-Acetyl-6-bromo-1,2,3,4-tetrahydroquinoline 22190-40-5
Tetrahydroquinoline 25448-04-8
2-((3,4-Dihydroxyphenethylamino)methyl)-1,2,3,4-tetrahydroquinoline dihydrobromide 27114-40-5
7-Nitro-1,2,3,4-tetrahydroquinoline 30450-62-5
6-Methyl-1,2,3,4-tetrahydroquinoline-1-carboxaldehyde 34847-16-0
N-(3,4,5-Trimethoxybenzoyl)-1,2,3,4-tetrahydroquinoline 34952-16-4

6-Fluoro-1,2,3,4-tetrahydro-2-methylquinoline

42835-89-2

2,7-Dimethyl-1,2,3,4-tetrahydroquinoline 42835-92-7

N-Carboxymethyl-6-(2,2-dicyanovinyl)-1,2,3,4-tetrahydroquinoline

47072-52-6

1,3,3-Trimethyl-1,2,3,4-tetrahydroquinoline 53207-55-9
2,7-Dimethyl-1-(2-hydroxyethyl)-1,2,3,4-tetrahydroquinoline 53817-43-9
8-Amino-1,2,3,4-tetrahydroquinoline 54012-92-9
7-Hydroxy-1,2,3,4-tetrahydroquinoline 58196-33-1
N-Dichloroacetyl-6-hydroxy-tetrahydroquinoline 62265-67-2
Quinfamide 62265-68-3
1-Tetrahydroquinolyl-3,3-diphenylpropane hydrochloride 62469-22-1

1-Carbamoyl-1,2,3,4-tetrahydroquinoline

63098-90-8

N-(2-(4-Morpholino)ethyl)-1,2,3,4-tetrahydroquinoline hydrochloride 63680-74-0
8-(3-Aminopropyl)amino-6-methoxy-1,2,3,4-tetrahydroquinoline hydrochloride 63680-69-3
1-Ethyl-2-(1-(2-hydroxyethyl)-2,2,4-trimethyl-1,2,3,4-tetrahydroquinoline- 6-yl)benz(c,d)indolium chloride 63817-45-8
N-Methylurethane of hydrochloride of 7-hydroxy-1-methyl-1,2,3,4-tetrahydroquinoline 63982-20-7
2-Benzylaminomethyl-1,2,3,4-tetrahydroquinoline hydrochloride 68339-85-5
2-(3',4'-Dimethoxybenzylaminomethyl)-1,2,3,4-tetrahydroquinoline hydrochloride 68339-86-6
6-(2-Cyano-4,6-dinitrophenyl)azo-N-ethyl-2,2,4-trimethyl-7-propionamido- 1,2,3,4-tetrahydroquinoline 68900-95-8
N-(2-Quinuclidinmethyl)-1,2,3,4-tetrahydroquinoline 69907-19-3
1-Ethyl-7-hydroxy-1,2,3,4-tetrahydroquinoline 71130-68-2
1-Cyano-3,4-dichloromethylene-2-methoxy-1,2,3,4-tetrahydroquinoline 71636-22-1
7-Amino-1-(2-(2-ethoxyethoxy)ethyl)-2,2,4-trimethyl-1,2,3,4-tetrahydroquinoline 71673-14-8
7-Nitro-1-(2-(2-ethoxyethoxy)ethyl)-2,2,4-trimethyl-1,2,3,4-tetrahydroquinoline 71673-19-3
N-(2-Sulfatoethyl)-2,2,4,7-tetramethyl-1,2,3,4-tetrahydroquinoline 71673-01-3
1-(2-(2-Ethoxyethoxy)ethyl)-2,2,4-trimethyl-1,2,3,4-tetrahydroquinoline 71673-20-6
7-Acetamido-1-(2-(2-ethoxyethoxy)ethyl)-2,2,4-trimethyl-1,2,3,4-tetrahydroquinoline 71673-02-4
7-Nitro-1,2,3,4-tetrahydroquinoline, hydrogen sulfate 73987-44-7
8-(tert-Butyl)-1,2,3,4-tetrahydroquinoline 75413-99-9
6-(tert-Butyl)-1,2,3,4-tetrahydroquinoline 75413-98-8

1-Methyl-6-(4-nitrophenylazo)-1,2,3,4-tetrahydroquinoline

79579-23-0

2,3-Dihydro-6-chloro-1-(1-oxopropyl)-4(1H)-quinolinone 4-oxime 81075-14-1
(E)-6-Methyl-1-(2-methyl-1-oxo-2-butenyl)-1,2,3,4-tetrahydroquinoline 81719-55-3
6-Bromo-4-oximino-1-methylcarbamoyl-1,2,3,4-tetrahydroquinoline 81892-50-4
6-Bromo-4-oximino-1-isobutyryl-1,2,3,4-tetrahydroquinoline 81892-48-0
6-Chloro-4-oximino-1-methoxycarbonyl-1,2,3,4-tetrahydroquinoline 81892-42-4
6-Chloro-4-oximino-1-phenylacetyl-1,2,3,4-tetrahydroquinoline 81892-39-9
6-Fluoro-4-oximino-1-propionyl-1,2,3,4-tetrahydroquinoline 81892-46-8
6-Chloro-4-oximino-1-dimethylcarbamoyl-1,2,3,4-tetrahydroquinoline 81892-52-6
6-Fluoro-4-oximino-1-dimethylcarbamoyl-1,2,3,4-tetrahydroquinoline 81892-51-5
6-Chloro-4-oximino-1-isovaleryl-1,2,3,4-tetrahydroquinoline 81892-38-8
6-Chloro-4-oximino-1-valeryl-1,2,3,4-tetrahydroquinoline 81892-37-7
6-Bromo-4-oximino-1-cinnamoyl-1,2,3,4-tetrahydroquinoline 81892-49-1
6-Bromo-4-oximino-1-dimethylcarbamoyl-1,2,3,4-tetrahydroquinoline 81892-53-7
6-Bromo-4-oximino-1-propionyl-1,2,3,4-tetrahydroquinoline 81892-47-9
6-Chloro-4-oximino-1-acetyl-1,2,3,4-tetrahydroquinoline 81892-35-5
6-Fluoro-4-oximino-1-methoxycarbonyl-1,2,3,4-tetrahydroquinoline 81892-41-3
6-Fluoro-4-oximino-1-ethoxycarbonyl-1,2,3,4-tetrahydroquinoline 81892-44-6
6-Bromo-4-oximino-1-methoxycarbonyl-1,2,3,4-tetrahydroquinoline 81892-43-5
6-Chloro-4-oximino-1-cinnamoyl-1,2,3,4-tetrahydroquinoline 81892-40-2
6-Chloro-4-oximino-1-butyryl-1,2,3,4-tetrahydroquinoline 81892-36-6
6-(sec-Butyl)-1,2,3,4-tetrahydroquinoline 84682-11-1
8-(sec-Butyl)-1,2,3,4-tetrahydroquinoline 84682-10-0
6-Bromo-4-oximino-1-acetyl-1,2,3,4-tetrahydroquinoline 90181-94-5
1,2,3,4-Tetrahydroquinolinepropionic acid 91641-02-0
6-Tricyanovinyl-1,2,3,4-tetrahydroquinoline 97460-75-8
1,6-Dimethyl-1,2,3,4-tetrahydroquinoline hydrochloride 102259-73-4
2-Methyl-1-(2-oxazolin-2-yl)-1,2,3,4-tetrahydroquinoline, hydrobromide 102259-76-7
8-((2-Benzimidazolyl)sulfinylmethyl)-1-ethyl-1,2,3,4-tetrahydroquinoline 112644-23-2
5,6,7,8-Tetrahydro-2-((4-methoxyphenyl)amino)-3-quinolinecarboxamide 117052-10-5
5,6,7,8-Tetrahydro-2-((3-methylphenyl)amino)-3-quinolinecarboxamide 117052-09-2
5,6,7,8-Tetrahydro-2-((2-chlorophenyl)amino)-3-quinolinecarboxamide 117052-13-8
5,6,7,8-Tetrahydro-2-((2-methoxyphenyl)amino)-3-quinolinecarboxamide 117052-11-6
5,6,7,8-Tetrahydro-2-((4-chlorophenyl)amino)-3-quinolinecarboxamide 117052-12-7
5,6,7,8-Tetrahydro-2-((2-methylphenyl)amino)-3-quinolinecarboxamide 117052-08-1
5,6-Epoxy-5,6,7,8-tetrahydroquinoline 130536-45-7
7,8-Epoxy-5,6,7,8-tetrahydroquinoline 130536-46-8
2-Carboxy-4-(carboxymethyl)-5,7-dichloro-1,2,3,4-tetrahydroquinoline 132691-83-9
4-trans-2-Carboxy-5,7-dichloro-4-phenylaminocarbonylamino- 1,2,3,4-tetrahydroquinoline 139051-78-8
syn-5,6-Dihydroxy-7,8-epoxy-5,6,7,8-tetrahydroquinoline 142044-40-4
anti-5,6-Dihydroxy-7,8-epoxy-5,6,7,8-tetrahydroquinoline 142078-76-0
trans-Quinoline-5,6,7,8-dioxide 142129-81-5
cis-Quinoline-5,6,7,8-dioxide 142184-78-9

6-(2,2-Dicyanovinyl)-N-(2-hydroxyethyl)-1,2,3,4-tetrahydroquinoline

142978-25-4

1-Methyl-8-((morpholin-2-yl)methoxy)-1,2,3,4-tetrahydroquinoline monomethane sulfonate 152985-36-9
7-Amino-1,2,3,4-tetrahydroquinoline 153856-89-4
5,6,7,8-Tetrahydro-2-butoxy-3-quinolinecarboxamide 171011-09-9
5,6,7,8-Tetrahydro-2-propoxy-3-quinolinecarboxamide 171011-07-7
5,6,7,8-Tetrahydro-2-(1-methylethoxy)-3-quinolinecarboxamide 171011-08-8
5,6,7,8-Tetrahydro-2-(2-methylpropoxy)-3-quinolinecarboxamide 171011-10-2
5,6,7,8-Tetrahydro-2-ethoxy-3-quinolinecarboxamide 171011-06-6

1-(4-tert-Butylbenzoyl)-1,2,3,4-tetrahydroquinoline

298230-96-3

1-(3,5-Dinitrobenzoyl)-1,2,3,4-tetrahydroquinoline

301674-76-0

7-Amino-1-ethyl-1,2,3,4-tetrahydroquinoline

303982-14-1

7-Amino-1-methyl-1,2,3,4-tetrahydroquinoline 304690-94-6

1-(1-Naphthoyl)-1,2,3,4-tetrahydroquinoline

306745-50-6

1-(2,4-Dichlorobenzoyl)-1,2,3,4-tetrahydroquinoline

306766-49-4

1-(2-Chlorobenzoyl)-1,2,3,4-tetrahydroquinoline

329058-15-3

1-((3-Methyl-1-benzofuran-2-yl)carbonyl)-1,2,3,4-tetrahydroquinoline

617694-02-7