N,N-DIMETHYLETHANOLAMINE

PRODUCT IDENTIFICATION

CAS NO. 108-01-0

n,n-DIMETHYLETHANOLAMINE

EINECS NO. 203-542-8
FORMULA (CH3)2NCH2CH2OH
MOL WT. 89.14
H.S. CODE 2922.19

TOXICITY

Oral rat LD50: 2000 mg/kg
SYNONYMS 2-(Dimethylamino)Ethanol; N,N-Dimethyl-N-ethanolamine;
N,N-Dimethyl-2-aminoethanol; beta-Dimethylaminoethyl alcohol; beta-hydroxyethyldimethylamine; Ddimethylaminoethanol; Deanol; Dimethylethanolamine; Dimethylaminoaethanol (German); N,N-Dimethyl-2-Hydroxyethylamine; N,N-Dimethylaminoethanol; N,N-dimethyl-N-(2-hydroxyethyl)amine;

SMILES

 

CLASSIFICATION

 

PHYSICAL AND CHEMICAL PROPERTIES

PHYSICAL STATE clear to pale yellow liquid
MELTING POINT -70 C
BOILING POINT

133 - 135 C

SPECIFIC GRAVITY 0.88 - 0.89
SOLUBILITY IN WATER soluble (miscible in alcohol and ether)
pH

 

VAPOR DENSITY 3.03

AUTOIGNITION

 

NFPA RATINGS

2; Flammability: 2; Reactivity: 0
REFRACTIVE INDEX

 

FLASH POINT

40 C

STABILITY

Stable under ordinary conditions

APPLICATIONS

Alkanolamines have the combined physical and chemical characteristics of both alcohols and amines in one molecule, which makes them useful intermediates in the synthesis of various target molecules for the use in many diverse areas such as pharmaceutical, urethane catalysts, coatings, personal care, products, Water treatments, corrosion inhibitors, and gas treating industries. There are 1°, 2º or 3º nitrogen atom and one hydroxyl group at least in alkanolamines. Alkanolamines react with inorganic acids carboxylic acids to form salts, soaps, esters, or amides. Alkanolamines are used in both water- based and solvent-based coatings to enhance the solubility, reducibility, pigment dispersing and pH stability. They are used in cathodic electrodeposition systems and as a catalyst for chain-extend. Alkanolamines are used to prepare surface-active soaps through reaction with fatty acids. Surface-active soaps are used commercially as a emulsifier, lubricants, detergents, pesticides and personal care products. Alkanolamines maintain a constant alkalinity in the boiling water flows and condensate not to form solid products which would impede line flow. This function is applied for corrosion Inhibits. Alkanolamines are widely employed in the preparation of  water soluble cationic flocculants and ion exchange resins which adsorb solid and colloidal particles by electrostatic attraction. They are used for water treatment industry. Alkanolamines and their derivatives are widely used as intermediates for the production of active pharmaceutical ingredients such as procaine, antihistamines analgesics from N,N-dimethylethanolamine or N-methyldiethanolamine. Alkanolamines are used to remove Hydrogen sulfide (H2S) and CO2 gas from gas streams in natural and refinery gas operations. Dimethylaminoethanol used for the synthesis of dyestuffs, textile auxiliaries, pharmaceuticals (such as procaine), and corrosion inhibitors. It is used as an antidepressant for water treatment. It is used as an emulsifier and as a catalyst of urethane foaming. N,N-dimethylethanolamine is used  in making sulfurized oils for extreme-pressure lubricants and to lower down the pour point of lubricating oils. N,N-dimethylethanolamine is one of major raw materials to prepare water-soluble ion exchange resins and cationic polymeric flocculants.

Pharmaceutical grade of dimethylethanolamine, called Deanol, is used as an antidepressive or antidyskinesia agent to treat movement disorders. Dyskinesia is can be caused by long-term use of antipsychotic drugs or dopamine antagonists. Dyskinesia appears even after the drugs are no longer taken. Members of antidyskinesia agent include;

Antidyskinesia agent

CAS RN

Deanol 108-01-0
Haloperidol 52-86-8
Pimozide 2062-78-4
Procyclidine 77-37-2
Tetrabenazine 58-46-8
Tiapride 51012-32-9
Trihexyphenidyl 144-11-6
SALES SPECIFICATION

APPEARANCE

clear to pale yellow liquid
ASSAY

98.0% min

AMINE CONTENT

1.0% max

TRANSPORTATION
PACKING 175kgs in drum
HAZARD CLASS 8 (Packing Group: II)
UN NO. 2051
OTHER INFORMATION
Hazard Symbols: C, Risk Phrases: 10/36/37/38, Safety Phrases: 28A