Organosulfone compounds are widely used in refineries, steamcrackers,
aromatic extraction and
petrochemical manufacturing as they acts as;
- Hydrotreating catalysts
- Initial
catalyst improvers
- Sulfur sources
- Catalyst presulfiding
- Natural gas sulfur recovery
Organosulfone compounds are also
used in;
- Organic synthesis as organosulfur
sources into target organic molecules for the manufacture of pharmaceuticals,
adhesives biocides and agricultural products.
- Polymer
production
- Lubricant and
fuel additives for
extreme pressure functionality
- Extraction and reaction solvent
- Metal
treatment
- Fungicide
Sulfoxide (R2SO) is any of various organic sulfur compounds having the group -SO
(sulfinyl group) whereas sulfone (RSOOR) with the group -SO2 (sulfonyl group).
They are derived from oxidation of sulfides ((R-S-R). Thioethers (organic sulfides) can be oxidized either to oxidation state -1
disulfides (R-S-S-R) or to oxidation state 0 sulfoxides (R-S(=O)-R)
which can be
further oxidized to the corresponding oxidation state +2 sulfones (R-S(=O)2-R)
depending on the structure of the thioether. They are widely used as solvent of
both extraction and reaction as well as intermediates for the synthesis of
textile chemicals and pharmaceuticals and agrochemicals.
Dimethyl Sulfone is
an effective extraction solvent and solvent improver
for the separation of aromatic compounds
(benzene, toluene and xylenes) from aliphatic hydrocarbons, and for fractionation of
unsaturated components (olefins and alkynes) from saturated feedstock. It is used
as a thermally stable medium for carrying out chemical reactions in polymerization
process as well as to make
pharmaceuticals, agrochemicals, paint and
coating materials and biocides. Dimethyl Sulfone is known that it is involved in
hair and nail growth in the body.
The common examples of sulfone
compounds are dapsone (4,4'-sulfonylbisbenzenamine) and its derivative. Dapsone
(4,4'-sulfonylbisbenzenamine) is a parent compound in preparing sulfonamide
antibacterial agents such as acedapsone, acetosulfone, glucosulfone, sulfoxone
and solapsone. Dapsone and its derivatives have bacteriostatic activity against
a broad spectrum of gram-negative and gram-positive organisms. Dapsone is a
primary treatment for Dermatitis herpetiformis and in the treatment of leprosy
(Mycobacterium leprae infections) leads to apparent improvementas. It is used in
the prophylaxis of falciparum malaria. It is a white crystalline powder; melting
point 175 - 180C; insoluble in water and vegetable oils. Dapsone is also widely
used in polymer industry as a cross linkage agent in manufacturing polysulfone
amide engineering plastics. Sulfone-containing engineering plastics are
thermally stable and have high resistance property to acids and alkalis.
Tazobactam is a penicillanic acid sulfone derivative which acts as a
beta-lactamase inhibitor similar to sulbactam. Tazobactam is used in combination
with piperacillin to widen the spectrum of activity. Sulfone class compounds
which have a sulfonyl group attached to two carbon atoms are active as an
antibiotic.
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