DIMETHYL SULFONE

PRODUCT IDENTIFICATION

CAS NO. 67-71-0

DIMETHYL SULFONE

EINECS NO. 200-665-9
FORMULA (CH3)2SO2
MOL WT. 94.13
H.S. CODE  

TOXICITY

Oral rat LD50: >5 gm/kg
SYNONYMS SulfonylbisMethane; Methylsulfonylmethane;
Dimetil sulfona (Spanish); Diméthylsulfone (French); Sulphonylbismethane; Methyl sulfone; MSM;

SMILES

 

CLASSIFICATION

 

PHYSICAL AND CHEMICAL PROPERTIES

PHYSICAL STATE white crystalline flakes
MELTING POINT 108 - 110 C
BOILING POINT 238 C
SPECIFIC GRAVITY  
SOLUBILITY IN WATER 150 g/l
pH

 

VAPOR DENSITY  
AUTOIGNITION

 

NFPA RATINGS Health: 1; Flammability: 1; Reactivity: 0

REFRACTIVE INDEX

1.4775 - 1.4790
FLASH POINT 143 C
STABILITY Stable under ordinary conditions. Hygroscopic

APPLICATIONS

Organosulfone compounds are widely used in refineries, steamcrackers, aromatic extraction and petrochemical manufacturing as they acts as;
  • Hydrotreating catalysts
  • Initial catalyst improvers
  • Sulfur sources
  • Catalyst presulfiding
  • Natural gas sulfur recovery

Organosulfone compounds are also used in;

  • Organic synthesis as organosulfur sources into target organic molecules for the manufacture of pharmaceuticals, adhesives biocides and agricultural products.
  • Polymer production
  • Lubricant and fuel additives for extreme pressure functionality
  • Extraction and reaction solvent
  • Metal treatment
  • Fungicide

Sulfoxide (R2SO) is any of various organic sulfur compounds having the group -SO (sulfinyl group) whereas sulfone (RSOOR) with the group -SO2 (sulfonyl group). They are derived from oxidation of sulfides ((R-S-R). Thioethers (organic sulfides) can be oxidized either to oxidation state -1 disulfides (R-S-S-R) or to oxidation state 0 sulfoxides (R-S(=O)-R) which can be further oxidized to the corresponding oxidation state +2 sulfones (R-S(=O)2-R) depending on the structure of the thioether. They are widely used as solvent of both extraction and reaction as well as intermediates for the synthesis of textile chemicals and pharmaceuticals and agrochemicals.

Dimethyl Sulfone is an effective extraction solvent and solvent improver for the separation of aromatic compounds (benzene, toluene and xylenes) from aliphatic hydrocarbons, and for fractionation of unsaturated components (olefins and alkynes) from saturated feedstock. It is used as a thermally stable medium for carrying out chemical reactions in polymerization process as well as to make pharmaceuticals, agrochemicals, paint and coating materials and biocides. Dimethyl Sulfone is known that it is involved in hair and nail growth in the body.

The common examples of sulfone compounds are dapsone (4,4'-sulfonylbisbenzenamine) and its derivative. Dapsone (4,4'-sulfonylbisbenzenamine) is a parent compound in preparing sulfonamide antibacterial agents such as acedapsone, acetosulfone, glucosulfone, sulfoxone and solapsone. Dapsone and its derivatives have bacteriostatic activity against a broad spectrum of gram-negative and gram-positive organisms. Dapsone is a primary treatment for Dermatitis herpetiformis and in the treatment of leprosy (Mycobacterium leprae infections) leads to apparent improvementas. It is used in the prophylaxis of falciparum malaria. It is a white crystalline powder; melting point 175 - 180C; insoluble in water and vegetable oils. Dapsone is also widely used in polymer industry as a cross linkage agent in manufacturing polysulfone amide engineering plastics. Sulfone-containing engineering plastics are thermally stable and have high resistance property to acids and alkalis. Tazobactam is a penicillanic acid sulfone derivative which acts as a beta-lactamase inhibitor similar to sulbactam. Tazobactam is used in combination with piperacillin to widen the spectrum of activity. Sulfone class compounds which have a sulfonyl group attached to two carbon atoms are active as an antibiotic.

SALES SPECIFICATION

APPEARANCE

white crystalline flakes

ASSAY

99.8% min

MELTING POINT

107 - 111 C

HEAVY METALS

10ppm max

RESIDUE ON IGNITION

0.1% max

WATER

0.05% max

TRANSPORTATION
PACKING

25kgs in fiber drum

HAZARD CLASS  
UN NO.  
OTHER INFORMATION
Hazard Symbols: , Risk Phrases: , Safety Phrases: 24-25