1-THIOGLYCEROL

PRODUCT IDENTIFICATION

CAS NO. 96-27-5

1-THIOGLYCEROL

EINECS NO. 202-495-0
FORMULA HSCH2CH(OH)CH2OH
MOL WT. 108.16

H.S. CODE

 

TOXICITY

 

SYNONYMS 3-Mercapto-1,2-propanediol; alpha-Thioglycerol;
alpha-Thioglycerol; Glycerol-1-thiol; 1-Thio-2,3-propanediol; 2,3-Dihydroxypropanethiol; Monothioglycerin; 3-Mercaptopropane-1,2-diol; 3-Sulfanyl-1,2-propanediol;
DERIVATION  

CLASSIFICATION

 

PHYSICAL AND CHEMICAL PROPERTIES (90% in Aq. Solution)

PHYSICAL STATE clear to yellowish viscous solution
MELTING POINT  
BOILING POINT 118 C at 5 mmHg
SPECIFIC GRAVITY 1.23
SOLUBILITY IN WATER slightly soluble (miscible with alcohol, insoluble in ether)
pH  
VAPOR DENSITY

 

AUTOIGNITION

 

NFPA RATINGS

 

REFRACTIVE INDEX

 
FLASH POINT

 

STABILITY

Stable under ordinary conditions

APPLICATIONS

The only existing three-carbon sugar alcohol (triitol) is glycerol. Low molecular weight thiols or their esters such as 2-mercaptoethanol, 1-thioglycerol and dithiothreitol denatures the proteins by reducing disulfide linkages leading to tautomerization and breaking up quaternary protein structure. They are involved in protein processing, induction of genes, oligonucleotide synthesis. They have been studied as anti-cancer agents by acting as alkylating agents to damage the cancer cell DNA.
SALES SPECIFICATION

APPEARANCE

clear to yellowish viscous solution

ASSAY (G.C)

90.0% min

TRANSPORTATION
PACKING
 
HAZARD CLASS  
UN NO.  
OTHER INFORMATION
Hazard Symbols: XI, Risk Phrases: 36/37/38, Safety Phrases: 23