2-AMINOINDANE

PRODUCT IDENTIFICATION
CAS NO. 2975-41-9; 2338-18-3 (hydrochloride)

2-AMINOINDANE

EINECS NO. 221-021-3
FORMULA C9H11N
MOL WT. 133.19

H.S. CODE

  

TOXICITY

 
SYNONYMS 2,3-dihydro-1H-Inden-2-amine; Indan-2-amine;
DERIVATION

 

CLASSIFICATION

  

PHYSICAL AND CHEMICAL PROPERTIES

PHYSICAL STATE yellow to brown liquid
MELTING POINT  
BOILING POINT 100 - 103 C at 30 mm Hg
SPECIFIC GRAVITY 1.02 - 1.03
SOLUBILITY IN WATER  
pH  
VAPOR DENSITY  

AUTOIGNITION

 

NFPA RATINGS

  

REFRACTIVE INDEX

 1.561
FLASH POINT  
STABILITY

Stable under ordinary conditions

GENERAL DESCRIPTION & APPLICATIONS
Indene is a clear to yellowish liquid ; boils at 181C and melts at -2 C. It is a polynuclear hydrocarbon compound with a five-membered ring fused to benzene ring. Indan, 2,3-dihydroindene, is a clear to yellowish liquid; boiling point 177 C;  insoluble in water; soluble in alcohol and ether. Indanone is a ketone form of indane. These compounds can be obtained from coal tar distillation; used as solvents, raw material for synthetic resins and to make other organic compounds such as pharmaceutical ingredients and agrochemicals especially plant growth regulators. Some indane compounds have the characteristic odour and  are used for the preparation of perfumes and flavouring agents. A main industrial application of indene is the production of indene/cumarone thermoplastic resin. Indanedione is the nucleus of synthetic anticoagulants for the treatment of disorders in which there is excessive or undesirable clotting, such as thrombophlebitis, pulmonary embolism, and certain cardiac conditions. They inhibits the hepatic synthesis of the vitamin K–dependent coagulation factors. Anticoagulants act as rodenticide by causing massive hemorrhaging. Indanedione class anticoagulants or rodenticides include diphenadione, phenindione,  pindone, and valone. Indane class compounds show various functions such as light and temperature sensitivity, heat resistance, conductivity, emittability, corrosion resistance and detection of amino groups. They are used in the applications of  thermo and light sensitizer, liquid crystal chemistry, optical brightening agents, luminescence chemistry, spectrophotometric analysis, molecular chemistry, organometallic-complexes and biochemorphology industry.

Molecular compounds of aminoindan show pharmacological actions of dopamine antagonist, monoamine oxidase inhibitor, anti-arrhythmia agent, dopamine, serotonin & noradrenaline uptake inhibitor, hypoglycemic agent, and neuroprotective agent.

2-Aminoindan is used as a hypoglycemic agent that stimulates the release of insulin and used in the treatment of diabetes mellitus

Molecular compounds of aminoindan

Product

CAS RN
N-Methyl-N-2-propynyl-1-indanamine hydrochloride 1506-17-8
N-2-Propynyl-1-indanamine 1875-50-9
N,N'-Bis(1-indanyl)-1,4-cyclohexenebis(methylamine) dihydrochloride 2077-76-1
2-Indanamine hydrochloride 2338-18-3
2-Aminoindan 2975-41-9
N,N'-Bis(1-indanyl)-1,4-bicyclo(2.2.2)octanebis(methylamine) dihydrochloride 5085-35-8
Dimefadane [USAN:INN] 5581-40-8
N-(2-Morpholinoacetyl)-N-methyl-1-indanamine 6514-53-0
N-(2-Dimethylaminoacetyl)-1-indanamine 6514-52-9
N-(2-Diethylaminoacetyl)-1-indanamine picrate 6514-55-2
N-(2-Dimethylaminobutyryl)-1-indanamine 6520-58-7
N-(2-Morpholinopropionyl)-1-indanamine 6520-57-6
N-(2-Dimethylaminopropionyl)-N-methyl-1-indanamine hydrochloride 6520-63-4
N-(2-Diethylaminopropionyl)-1-indanamine picrate 6520-65-6
N-(2-Morpholinoacetyl)-1-indanamine 6520-54-3
N-(2-Diethylaminobutyryl)-1-indanamine picrate 6520-59-8
N-(2-Morpholinobutyryl)-1-indanamine 6520-60-1
N-(2-Morpholinopropionyl)-N-methyl-1-indanamine hydrochloride 6547-50-8
N-(2-(2-Benzylphenoxy)ethyl)-2-indanamine hydrochloride 10429-58-0
Aminoindanol hydrochloride 13935-78-9
2-Aminoindan-1-ol 15028-16-7
Methindione 20915-57-5
Indan-5-amine 24425-40-9
N-Methyl-N-2-propynylindanamine 32033-21-9
Indan-4-amine 32202-61-2
Aprindine hydrochloride 33237-74-0
N-Phenylindan-2-amine 33237-72-8
N-(2-Oxazolin-2-yl)-1-indanamine 33587-61-0
1-Aminoindan 34698-41-4
4,5-Dihydroxy-N,N-dimethyl-2-indanamine hydrobromide 35059-16-6
Aprindine 37640-71-4
trans-1-Benzoyloxy-2-dimethylaminoindan hydrochloride 39787-53-6
cis-1-Benzoyloxy-2-dimethylaminoindan hydrochloride 39787-52-5
N,N-Dimethyl-2-aminoindane 51864-45-0
Protoadamantane-4-amine hydrochloride 59177-69-4
N-Methyl-4-protoadamantaneamine hydrochloride 59177-70-7
N-Benzyl-4-protoadamantaneamine hydrochloride 59177-71-8
N-(2-Hydroxyethyl)-4-protoadamantaneamine hydrochloride 59177-73-0
N-(2-Morpholinobutyryl)-2-phenyl-1-indanamine 63992-13-2
N-(2-Diethylaminopropionyl)-2-phenyl-1-indanamine hydrochloride 63992-25-6
5,6-Dimethoxy-N,N-dimethyl-1-indanamine hydrochloride 63992-26-7
N-(2-Dimethylaminoacetyl)-2-phenyl-1-indanamine 63992-27-8
N-(2-Morpholinoacetyl)-2-phenyl-1-indanamine hydrochloride 63992-11-0
N-(2-Diethylaminoacetyl)-2-phenyl-1-indanamine hydrochloride 63992-23-4
N-(2-Morpholinopropionyl)-2-phenyl-1-indanamine 63992-14-3
N-(2-Diethylaminobutyryl)-2-phenyl-1-indanamine hydrochloride 63992-24-5
N-(2-Dimethylaminobutyryl)-2-phenyl-1-indanamine 63992-28-9
N-(2-Dimethylaminopropionyl)-2-phenyl-1-indanamine 63992-10-9
N-(2-Morpholinobutyryl)-N-methyl-1-indanamine hydrochloride hemihydrate 63992-12-1
N-Phenylethyl-4-protoadamantaneamine hydrochloride 67293-84-9
N-(p-Chlorobenzyl)-4-protoadamantaneamine hydrochloride 67293-83-8
2-Di-n-propylaminoindan 71096-41-8
N-(2-Oxazolinyl)-4-indanamine 77733-21-2
7-Methyl-N-(2-oxazolinyl)-4-indanamine 77733-22-3
Indatraline 86939-10-8
N,N-Dimethyl-3-(4'-bromophenyl)-1-indanamine 86945-54-2
N,N-Dimethyl-3-(2',4'-dichlorophenyl)indanamine 86946-16-9
trans-(+-)-3-(3,4-Dichlorophenyl)-2,3-dihydro-N-methyl-1H-inden-1-amine 97229-15-7
1-(Dimethylamino)methyleneaminoindan 101398-65-6
N-(2-Oxazolin-2-yl)-2-indanamine 101692-43-7
2-Methyl-N-(2-oxazolinyl)-4-indanamine 101692-41-5
5-Iodo-2-aminoindan 132367-76-1
5,6-Methylenedioxy-2-aminoindan 132741-81-2
5,6-Methylenedioxy-2-methylaminoindan 132741-82-3
5-Methoxy-6-methyl-2-aminoindan 132980-16-6
Rasagiline [INN] 136236-51-6
5,6-Dimethoxy-2-(dipropylamino)indan hydrochloride 153570-58-2
N,N-Dimethyl-3-(4'-iodophenyl)-1-indanamine 163076-45-7
1-Aminoindan-1,5-dicarboxylic acid 168560-79-0
Ladostigil 209394-27-4
SALES SPECIFICATION

APPEARANCE

 yellow to brown liquid
PURITY

99.0% min

REFRACTIVE INDEX

 1.561
TRANSPORTATION
PACKING  
HAZARD CLASS  
UN NO.  
OTHER INFORMATION
Hazard Symbols: XI, Risk Phrases: 36/37/38, Safety Phrases: 26-36