DESOGESTREL

PRODUCT IDENTIFICATION

CAS NO. 54024-22-5

DESOGESTREL

EINECS NO. 258-929-4
FORMULA C22H30O
MOL WT. 310.48

H.S. CODE

 

TOXICITY

 

SYNONYMS 13-Ethyl-11-methylene-18,19-dinor-17alpha-pregn-4-en-20-yn-17-ol;
(17alpha)-13-Ethyl-11-methylene-18,19-dinorpregn-4-en-20-yn-17-ol; 17alpha- ethynyl- 18-methyl -11-methylene-D4-estren-17β-ol;
DERIVATION

 

CLASSIFICATION

 

PHYSICAL AND CHEMICAL PROPERTIES

PHYSICAL STATE white to off-white crystalline powder
MELTING POINT 219 C
BOILING POINT

 

SPECIFIC GRAVITY

 

SOLUBILITY IN WATER

practically insoluble

pH  
VAPOR DENSITY

 

AUTOIGNITION

 

NFPA RATINGS

Health: 2 Flammability: 0 Reactivity: 0

REFRACTIVE INDEX

 

FLASH POINT

 

STABILITY

Stable under ordinary conditions

APPLICATIONS

Progesterone is a female sex hormone that plays an important physiological role to regularize and rebuild changes to the body caused by estrogen as well as in the luteal phase of the menstrual cycle. Its levels vary during the menstrual cycle. If fertilization occurs, it is produced during pregnancy by the placenta to prevent spontaneous abortion. If fertilization does not take place, the production of progesterone decreases and menstruation occurs. It is the hormone for the mammary glands of milk production. Progesterone is a steroid hormone consists chemically of four fused hydrocarbons containing the functional groups of ketone and aldehyde and two methyl branches. Progesterone is the precursor of all steroid hormones. It is an intermediate in the biosynthesis of androgens, estrogens, and the corticoids. Synthetic compounds with progesterone are used in the prevention of miscarriage, in the treatment of menstrual disorders. It is also used to develop a constituent of some oral contraceptives.  Progestins are a group of synthetic hormones similar to progesterone in structure and functions.

Members of progestin

Progestin

CAS RN

Algestone 595-77-7
Algestone acetophenide 24356-94-3
Allylestrenol 432-60-0
Altrenogest 850-52-2
Anagestone acetate 3137-73-3
Chlormadinone acetate 302-22-7
Cingestol 16915-71-2
Clogestone acetate 3044-32-4
Clomegestone acetate 424-89-5
Cyproterone acetate 427-51-0
Delmadinone acetate 13698-49-2
Desogestrel 54024-22-5
Dimethisterone anhydrous 79-64-1
Dimethisterone 41354-30-7
Dydrogesterone 152-62-5
Ethisterone 434-03-7
Ethynerone 3124-93-4
Ethynodiol diacetate 297-76-7
Etonogestrel 54048-10-1
Flurogestone acetate 2529-45-5
Gestodene 60282-87-3
Gestonorone caproate 1253-28-7
Gestrinone 16320-04-0
Hydroxyprogesterone caproate 630-56-8
Levonorgestrel 797-63-7
Lynestrenol 52-76-6
Medrogestone 977-79-7
Medroxyprogesterone 520-85-4
Medroxyprogesterone acetate 71-58-9
Megestrol 3562-63-8
Melengestrol acetate 2919-66-6
Methynodiol diacetate 23163-51-1
Norethindrone 68-22-4
Norethindrone acetate 51-98-9
Norethynodrel 68-23-5
Norgestimate 35189-28-7
Norgestomet 25092-41-5
Norgestrel 6533-00-2
Norgestrienone 848-21-5
Oxogestone phenpropionate 16915-80-3
Progesterone 57-83-0
Promegestone 34184-77-5
Quingestanol acetate 3000-39-3
Quingestrone 67-95-8
Tibolone 5630-53-5

Desogestrel is a synthetic progestational hormone with little androgenic activity, used often as a component of oral contraceptive in combination with an estrogen.

Contraceptive agents

Product

CAS RN.

5-Thio-D-glucose 20408-97-3
Algestone acetophenide 24356-94-3
Algestone 595-77-7
Anordiol 1045-30-3
Anordrin 56470-64-5
Bisecurin I 8056-92-6
Centchroman 31477-60-8
Chlormadinone acetate 302-22-7
Chlormadinone Acetate 302-22-7
Cloprostenol 40665-92-7
Cyproterone acetate 427-51-0
Desogestrel 54024-22-5
Diallyl disulfide 2179-57-9
Diallyl trisulfide 2050-87-5
Dienogest 65928-58-7
Dimethisterone 79-64-1

Estradiol benzoate

50-50-0

Estradiol cypionate 313-06-4
Estradiol valerate 979-32-8
Estropipate 7280-37-7
Ethinyl estradiol 57-63-6
Ethynodiol diacetate 297-76-7
Etonogestrel 54048-10-1
Fluprostenol 40666-16-8
Gestodene 60282-87-3
Gestrinone 16320-04-0
Gossypol acetic acid 12542-36-8
Gossypol 303-45-7
Levonorgestrel 797-63-7

L-Norgestrel

17489-40-6

Lonidamine 50264-69-2
Lynestrenol 52-76-6
Medroxyprogesterone acetate 71-58-9
Medroxyprogesterone 520-85-4
Megestrol 3562-63-8
Mestranol 72-33-3
Mifepristone 84371-65-3
Molinate 2212-67-1
Neem oil 8002-65-1
Nestorone 7759-35-5
Nonoxynol 15 26027-38-3
Norelgestromin 53016-31-2
Norethindrone enanthate 3836-23-5
Norethindrone acetate 51-98-9
Norethindrone 68-22-4
Norethynodrel 68-23-5
Norgestimate 35189-28-7
Norgestrel 6533-00-2
Norgestrienone 848-21-5
Octoxynol 9 9002-93-1
p-Coumaric acid 7400-08-0
Plumbagin 481-42-5
Polyethylene glycol octylphenyl ether 9036-19-5

Progesterone

57-83-0

Sodium polystyrene sulfonate 37349-16-9
Sulprostone 60325-46-4
Trestolone 3764-87-2
Triptolide 38748-32-2
Triptorelin 57773-63-4
SALES SPECIFICATION

APPEARANCE

white to off-white crystalline powder

IDENTIFICATION

Passes Test A(IR), B(TLC)

ASSAY

98.0 - 102.0%

OPTICAL ROTATION

+53° ~ +57°

SULFATED ASH

0.1% max

LOSS ON DRYING

0.5% max

TRANSPORTATION
PACKING

 

HAZARD CLASS  
UN NO.  
OTHER INFORMATION
Hazard Symbols: T, Risk Phrases: 45-63, Safety Phrases: 53-26-36/37/39