FISETIN

PRODUCT IDENTIFICATION
CAS NO. 528-48-3

FISETIN

EINECS NO. 208-434-4
FORMULA C15H10O6
MOL WT. 286.24

H.S. CODE

  

TOXICITY

  
SYNONYMS

Fisetin; Fietin; Viset; C.I. Natural Brown 1; C.I. 75620;

2-(3,4-Dihydroxyphenyl)-3,7-dihydroxy-4H-1-benzopyran-4-one; 3,3',4',7-Tetrahydroxyflavone; 5-Desoxyquercetin; Cotinin; Fustel; Fustet; 5-Desoxyquercetin; 2-(3,4-Dihydroxyphenyl)-3,7- dihydroxy-chromen-4-one;

SMILES

c1(c2cc(c(O)cc2)O)oc2c(ccc(c2)O)c(c1O)=O

CLASSIFICATION

Flavonol, Topoisomerase inhibitor, Catechol

EXTRA NOTES

 Fisetin is a flavonol, a structurally distinct chemical substance that belongs to the flavonoid group of polyphenols. It can be found in many plants, where it serves as a colouring agent. Its chemical formula was first described by Austrian chemist Josef Herzig in 1891 (Wikipedia)

PHYSICAL AND CHEMICAL PROPERTIES

PHYSICAL STATE

yellow to brown crystalline powder

MELTING POINT

330 C

BOILING POINT

 

SPECIFIC GRAVITY

 

SOLUBILITY IN WATER  
pH  
VAPOR DENSITY

 

REFRACTIVE INDEX

 

NFPA RATINGS

  

AUTOIGNITION

 

FLASH POINT

 

STABILITY Stable under normal conditions.

EXTERNAL LINKS & GENERAL DESCRIPTION

Wikipedia Linking - Fisetin

Google Scholar Search - Fisetin

Drug Information Portal (U.S. National Library of Medicine) - Fisetin

PubChem Compound Summary - Fisetin

KEGG (Kyoto Encyclopedia of Genes and Genomes) - Fisetin

Chemical Entities of Biological Interest (ChEBI) - Fisetin

http://www.ncbi.nlm.nih.gov/ - Fisetin

http://toxnet.nlm.nih.gov/
Hazardous Substances Data Bank - Fisetin

Local
A brown pigment found in woody plants. An analogue of quercetin. coloring principle of young fustic. Fustin (CAS RN: 20725-03-5) is the 2,3-Dihydrofisetin. Myricetin (3,3',4',5,5',7-Hexahydroxyflavone), Morin (2',3,4',5,7-pentahydroxyflavone), Fisetin (3,3',4',7-Tetrahydroxyflavone are naturally-occurring flavonoids. They have antioxidant properties which protect cells against oxygen radical damage. They are also reported inhibit xanthine oxidase, a free-radical generating enzyme and show and inhibit the oxidation of LDL (low density lipoprotein) by free radicals.

SALES SPECIFICATION

APPEARANCE

yellow to brown crystalline powder

IDENTIFICATION

passes Test IR

ASSAY

98% min (HPLC)

ASH

0.5% max

LOSS ON DRYING

3.0% max

HEAVY METALS

10ppm max

TRANSPORTATION
PACKING
 
HAZARD CLASS  
UN NO.  
OTHER INFORMATION
Hazard Symbols: , Risk Phrases: 36/37/38, Safety Phrases: 26-36

GENERAL DESCRIPTION OF FLAVONOID

Flavonoid is any member of a class of widely distributed biological natural products containing aromatic heterocyclic skeleton of flavan (2-Phenylbenzopyran) but no nitrogen in plants. Generally, flavonoids are biological pigments providing colours from red to blue in flowers, fruit and leaves. Besides their coloring in plants, flavonoids have important roles in the growth and development of plants; protection against UV-B radiation; forming antifungal barriers; antimicrobial, insecticidal and oestrogenic activities; plant reproduction. Flavonoids also exhibit a wide range of biological properties including anti-microbial, insecticidal and oestrogenic activities. Flavonoids are usually classified into main 6 subgroups as below plus flavans, neoflavonoids, flavonols, aurons, catechins according to the structural patterns.
  • Flavonols (Hydroxy derivatives of flavone):Fisetin, Galangin, Kaempferide, Kaempferol, Morin, Myricetin, Myricitrin, Quercetin, Quercetrin, Rhamnetin, Robinin, Rutin, Spirenoside
  • Flavones (skeleton: 2-phenylchromen-4-one): Apigenin, Baicalein, Chrysin, Diosmetin, Diosmin, Flavone, Luteolin, Rpoifolin,Tangeretin, Techtochrysin, Rhamnazin, Nobiletin, Natsudaidain.
  • Isoflavones (skeleton: 3-phenylchromen-4-one): Daidzin, Genistein, Irilone, Luteone, Prunetin, Pratensein,
  • Flavonones (derivation by reduction of the 2(3) C=C bond): Eriodictyol, Hesperidin, Hesperetin, Likvirtin, Naringin; Naringenin; Pinocembrin
  • Flavanols (derivation by reduction of the keto group):(+)-Catechin, (+)-Gallocatechin, (-)-Epicatechin (EC), (-)-Epigallocatechin (EGC), (-)-Epicatechin 3-gallate (ECG), (-)-Epigallocatechin 3-gallate (EGCG), Theaflavin, Theaflavin 3-gallate, Theaflavin 3'-gallate, Theaflavin 3,3' digallate, Thearubigins
  • Anthocyanidins (aglycones of the glycoside anthocyanins): Apigeninidin, Cyanidin, Delphinidin, Diosmetinidin, Guibourtinidin, Fisetinidin, Luteolinidin, Malvidin, Pelargonidin, Peonidin, Robinetinidin, Tricetinidin, Capensinidin, Petunidin, Europinidin, Aurentinidin, Columnidin, 5-Desoxy-malvidin, 5-Desoxy-peonidin, Hirsutinidin, Rosinidin

PRICE INFORMATION