| CAS
NO. |
93-14-1;
12041-73-5; 128707-44-8; 1336-67-0 |
|
| EINECS
NO. |
202-222-5 |
| FORMULA |
C10H14O4 |
| MOL
WT. |
198.22 |
|
H.S.
CODE
|
|
|
TOXICITY
|
|
| SYNONYMS |
Guaiacol glyceryl ether;
Glyceryl guaiacolate; |
| 3-(2-Methoxyphenoxy)-1,2-propanediol;
alpha-Glyceryl guaiacol ether; Equicol; Gecolate; Glyceryl guaiacyl ether;
D-threo-2-(Methylamino)-1-phenylpropan-1-ol;
Guaiacyl glyceryl ether; Guaiphenesin; 1,2-Dihydroxy-3-(2-methoxyphenoxy)propane;
Guaifenesine; Guaifenesinum; Guajacol-glycerinaether;
3-(o-Methoxyphenoxy)-1,2-propanediol; Guaiacol glycerin ether;
Glycerol alpha-(o-methoxyphenyl) ether; Guaiacol glycerol ether;
Guaifenesina; |
| DERIVATION |
|
|
CLASSIFICATION
|
|
|
PHYSICAL AND CHEMICAL PROPERTIES
|
| PHYSICAL
STATE |
white to almost white crystalline powder with a bitter taste |
| MELTING POINT |
78
- 82 C |
| BOILING
POINT |
|
| SPECIFIC GRAVITY |
|
| SOLUBILITY
IN WATER |
Soluble |
| pH |
|
| VAPOR DENSITY |
|
|
REFRACTIVE
INDEX
|
|
|
NFPA
RATINGS
|
|
|
AUTOIGNITION
|
|
|
FLASH
POINT
|
|
| STABILITY |
Stable under normal conditions. |
|
APPLICATIONS
|
|
Guaiacol is the
methyl ether of pyrocatechol. It is a main constituent of creosote obtained from
wood tar (mainly beech) by distillation mostly between 203 and 220 C. It is
synthesized from anisole also. The dimethyl ether of pyrocatechol is called
veratrol. They and their derivatives are used as an external antiseptic,
expectorant, gastric sedative, deodorant, and as a parasiticide.
Methoxyphenols are used in manufacturing stabilizers and
antioxidants for plastics and rubbers. They are also used in analgesics, local
anesthetic, flavorings, biocides, antiseptics.
Expectorant is an agent that promotes the ejection of phlegm, mucus or other
material from the throat, bronchi, trachea or lungs. It is used in many
cough preparations, guaifenesin is a common compound for this application. Expectorants
have muscle relaxing action.
|
| SALES
SPECIFICATION |
|
APPEARANCE
|
white to almost white crystalline powder with a bitter taste |
|
ASSAY
|
98.5 - 101.5% |
|
GUAIACOL |
500ppm
max
|
|
CHLORIDES |
250ppm
max
|
|
SULFATED
ASH
|
0.1%
max
|
|
LOSS
ON DRYING
|
0.5%
max
|
|
IMPURITIES |
1.0%
max
|
|
HEAVY
METALS
|
20ppm
max
|
|
PARTICLE
SIZE
|
20
mesh |
| TRANSPORTATION |
| PACKING |
|
| HAZARD CLASS |
|
| UN
NO. |
|
| OTHER
INFORMATION |
|
Hazard Symbols: XN,
Risk
Phrases: 22, Safety Phrases: 26-36 |
|
EXPECTORANTS
|
|
|