L-HOMOPHENYLALANINE ETHYL ESTER HCl

PRODUCT IDENTIFICATION

CAS NO. 90891-21-7

L-HOMOPHENYLALANINE ETHYL ESTER HCl

EINECS NO.  
FORMULA C6H5(CH2)2CH(NH2)CO2C2H5·HCl
MOL WT. 243.73

H.S. CODE

2922.49

TOXICITY

 

SYNONYMS S-(+)-2-Amino-4-phenylbutyric acid ethyl ester hydrochloride;
(S)-alpha-Amino-benzenebutanoic acid ethyl ester hydrochloride;
DERIVATION

 

CLASSIFICATION

 

PHYSICAL AND CHEMICAL PROPERTIES

PHYSICAL STATE white powder
MELTING POINT 152 - 157  C
BOILING POINT

 

SPECIFIC GRAVITY  
SOLUBILITY IN WATER  
pH  
VAPOR DENSITY

 

AUTOIGNITION

 

NFPA RATINGS

 

REFRACTIVE INDEX

 
FLASH POINT

 

STABILITY

Stable under ordinary conditions

APPLICATIONS

L-Homophenylalanine is an intermediate for the synthesis of ACE-inhibitors (angiotensin-converting enzyme inhibitor).
SALES SPECIFICATION

APPEARANCE

Off-White crystalline powder

ASSAY (HPLC)

99.0% min

OPTICAL PURITY

99.0% min

OPTICAL ROTATION +40.0° ± 1° (c=2 EtOH)
LOSS ON DRYING 0.3% max
TRANSPORTATION
PACKING
5kgs, 20kgs in can
HAZARD CLASS  
UN NO.  
OTHER INFORMATION
In chemical, the prefix homo- indicates the addition of one methyl(CH2) group to the main skeleton. Phenylalanine is an essential amino acid obtained in the levo form by hydrolysis of proteins (as lactalbumin). Branched amino-acids (Valine, Isoleucine and Leucine ) with tryptophan and phenylalanine (aromatic side chain amino acids) contribute to the structure of protein by the tendency of its side chain composed only of carbon and hydrogen to participate in hydrophobic interactions which determines the tertiary structure of the peptide chain. In addition to its role in protein synthesis, it is the metabolic precursor of the non-essential amino acid tyrosine which makes hormones, such as norepinephrine and epinephrine in the normal body. The prefix nor- describes normal structure which has no branched chain of carbon atoms. But in case of norepinephrine, it has one less methylene group than its homologue, epinephrine. Phenylalanine is also converted to phenylethylamine occuring naturally in the brain to elevate mood. It is used to treat depression, inflammation, chronic pain, Parkinson's disease. Phenylalanine is a key intermediate to make aspartame.