MESTANOLONE

PRODUCT IDENTIFICATION
CAS NO. 521-11-9

MESTANOLONE
EINECS NO. 208-302-6
FORMULA C20H32O2
MOL WT. 304.47

H.S. CODE

  

TOXICITY

 
SYNONYMS Mestanolona; methyl-DHT; 17alpha-Methyldihydrotestosterone;
 17beta-Hydroxy-17alpha-methyl-5alpha-androstan-3-one; 17alpha-Methyl-5alpha- androstan-17beta-ol-3-one;
DERIVATION

 

CLASSIFICATION

  

PHYSICAL AND CHEMICAL PROPERTIES
PHYSICAL STATE white to off-white crystalline powder
MELTING POINT 189 - 196 C
BOILING POINT

 
SPECIFIC GRAVITY

 
SOLUBILITY IN WATER

practically insoluble
pH  
VAPOR DENSITY

 

AUTOIGNITION

 

NFPA RATINGS

 Health: 2 Flammability: 0 Reactivity: 0

REFRACTIVE INDEX

 
FLASH POINT

 
STABILITY

Stable under ordinary conditions

APPLICATIONS
Testosterone is the major androgenic hormone that is responsible for the growth and development of masculine characteristics. It is produced in the Leydig cells (interstitial cells) of the testes. it regulates gonadotropic secretion and wolffian duct differentiation (formation of the epididymis, vas deferens, and seminal vesicle), and stimulates skeletal muscle. It is also responsible for other male characteristics and spermatogenesis after its conversion to dihydrotestosterone by 5alpha-reductase in peripheral tissue. Testosterone is converted to dihydrotestosterone in the target tissues where it appears to mediate many of the biological actions of testosterone. In addition, testosterone possesses protein anabolic properties, manifested by retention of nitrogen, calcium, phosphorus, and potassium, and is important in maintaining muscle mass and bone tissue in the adult male. It is also converted by aromatization to estradiol in peripheral tissue. It has been synthesized for replacement therapy, in the form of various esters having prolonged duration of effects, in treating male hypogonadism, cryptorchidism, frigidity, inoperable female breast cancer, oligospermia, to suppress lactation, and as an anabolic agent. Esters administered by subcutaneous, intramuscular injection, buccally or intramuscularly include;

· Cloxotestosterone (CAS RN: 53608-96-1)
· Ethisterone (Ethynyl testosterone, CAS RN: 434-03-7)
· Mestanolone (CAS RN: 521-11-9)
· 17alpha-Methyltestosterone (CAS RN: 58-18-4)
· Norethindrone (CAS RN: 68-22-4)
· Normethisterone (CAS RN: 514-61-4)
· Oxymetholone (CAS RN: 434-07-1)
· Silandrone (Testosterone trimethylsilyl ether, CAS RN: 5055-42-5)
· Testosterone Acetate (CAS RN: 1045-69-8)
· Testosterone Phenylpropionate (CAS RN: 1255-49-8)
· Testosterone Benzoate (CAS RN: 2088-71-3)
· Testosterone heptanoate (CAS RN: 315-37-7)
· Testosterone phenylacetate (CAS RN: 5704-03-0)
· Testosterone propionate (CAS RN: 57-85-2)
· Testosterone cypionate (CAS RN: 58-20-8)
· Testosterone ketolaurate (CAS RN: 5874-98-6)
· Testosterone Undecanoate
· Testosterone Glucuronide
· Testosterone Hemisuccinate

Alkylated testosterone at 17-alpha position such as methyltestosterone show more pharmacologic activity than testosterone itself. Methyltestosterone, a synthetic androgen, is used to treat testosterone deficiency in males. For females it is used in the relief of postpartum breast pain and swelling after pregnancy. It is used to treat the symptom of menopause and in the palliation of certain inoperable breast cancers. Methyltestosterone is a white to creamy white crystalline powder; melting point 162 - 167 C; practically insoluble in water; soluble in various organic solvents; administered orally or sublingually. The chemical designation is 17beta-hydroxy-17alpha-methyl-4-androsten-3-one.

Methandrostenolone, dehydro form of methyltestosterone, is one of the most effective anabolic steroids. It is used in a therapy of chronic coronary deficiency, in selected cases of interstitial-pituitary insufficiency, ulcerous renal diseases following by loss of protein and azotemia, and in the adjunctive treatment of senile and postmenopausal osteoporosis. Methandrostenolone is a white to creamy white crystalline powder; melting point 163 - 167 C; practically insoluble in water; slightly soluble in ether; soluble in ethanol, acetic acid; administered orally. The chemical designation is 17beta-Hydroxy-17-methylandrosta-1,4-dien-3-one.

Mestanolone (methyl-dihydrotestosterone) is the 17-alpha methylated stanolone, a semisynthetic form of dihydrotestosterone. Stanolone has the same activities with testosterone; used for anabolic effects and antineoplastic actions against in breast cancers. Mestanolone is the orally bioavailable form of stanolone.

SALES SPECIFICATION

APPEARANCE

 white to off-white crystalline powder

ASSAY
97.0 - 103.0%

OPTICAL ROTATION

 +7° ~ +10°

SOLVENT RESIDUES

0.25% max

MELTING POINT

189 - 196 C

LOSS ON DRYING

0.5% max
TRANSPORTATION
PACKING

 
HAZARD CLASS 6.1 (Packing Group: II)
UN NO. 2811
OTHER INFORMATION
European Hazard Symbols: T, Risk Phrases: 45-63, Safety Phrases: 53-26-36/37/39
ANABOLIC STEROIDS
Steroid

CAS RN
19-Norandrostenolone 17-cyclohexylpropionate 912-57-2
19-Nortestosterone homofarnesate 38911-59-0
4-Chloro-11-hydroxy-17-methylandrosta-1,4-dien-3-one 92780-95-5
Androst-5-ene-3beta,17beta-diol 521-17-5
Androstane-3,17-diol 25126-76-5
Bolandiol dipropionate 1986-53-4
Bolasterone 1605-89-6
Boldenone undecylenate 13103-34-9
Bolenol 16915-78-9
Demalon 2881-21-2
Dihydrotestosterone glucuronide 42037-24-1
Dihydrotestosterone propionate 855-22-1
Dromostanolone 58-19-5
Dromostanolone propionate521-12-0
Ethylestrenol 965-90-2
Fluoxymesterone 76-43-7
Formebolone 2454-11-7
Forplix 79127-94-9
Furazabol 1239-29-8
Mepitiostane 21362-69-6
Mestanolone 521-11-9
Mesterolone 1424-00-6
Methandriol 521-10-8
Methandrostenolone 72-63-9
Methenolone 153-00-4
Methenolone acetate 434-05-9
Methenolone enanthate 303-42-4
Methyltestosterone 58-18-4
Mibolerone 3704-09-4
Nandrolone 434-22-0
Nandrolone decanoate 360-70-3
Nandrolone Phenpropionate 62-90-8
Nandrolone p-hexyloxyphenylpropionate 52279-57-9
Norbolethone 1235-15-0
Norethandrolone 52-78-8
Oxandrolone 53-39-4
Oxymetholone 434-07-1
Quinbolone 2487-63-0
Ratibol 104270-00-0
Silabolin 77572-72-6
Stanolone 521-18-6
Stanolone benzoate 1057-07-4
Stanozolol 10418-03-8
Stenbolone acetate 1242-56-4
Testosterone cypionate 58-20-8
Testosterone propionate/Estradiol mixture 75026-40-3
Tibolone 5630-53-5
Tiomesterone 2205-73-4
Trenbolone 10161-33-8
Trenbolone acetate 49707-37-1
Trenbolone acetate 10161-34-9
Trenbolone acetate/Estradiol mixture 39450-18-5