METHYL INDOLE-2-CARBOXYLIC ACID

PRODUCT IDENTIFICATION
CAS NO 1202-04-6

METHYL INDOLE-2-CARBOXYLIC ACID
EINECS NO. 214-861-7
FORMULA C10H9NO2
MOL WT. 175.19

H.S. CODE

  

TOXICITY

  
SYNONYMS Indole-2-carboxylic acid methyl ester;
1H-Indole-2-carboxylic acid, methyl ester; 2-(Methoxycarbonyl)-indol; 1H-Indol-2-carboxilato de metilo; 1H-Indole-2-carboxylate de méthyle;
DERIVATION

 

CLASSIFICATION

  

PHYSICAL AND CHEMICAL PROPERTIES
PHYSICAL STATE off white crystals
MELTING POINT 151 - 153 C
BOILING POINT

 
SPECIFIC GRAVITY

 
SOLUBILITY IN WATER 470 (mg/l)

SOLVENT SOLUBILITY

  
pH  
VAPOR DENSITY

 

REFRACTIVE INDEX

 
AUTOIGNITION

 
NFPA RATINGS Health: 1 Flammability: 0 Reactivity: 0
FLASH POINT Not considered to be a fire hazard
STABILITY

Stable under ordinary conditions.

GENERAL DESCRIPTION & APPLICATIONS
Indole, also called Benzopyrrole, is a yellow crystalline powder with unpleasant aroma. It has the pyrrole ring (five-membered unsaturated ring structure composed of four carbon atoms and one nitrogen atom) which is fused benzene ring. There are tautomerer called indolenine (unsubstituted 3H-indole) and structural isomer, isoindole. But they are unstable. Indole occurs in some plants or in coal tar, and is formed in the intestine during putrefaction and by certain cultures of bacteria. it is commercially synthesized from phenylhydrazine and pyruvic acid. It is used in perfumery and in preparing tryptophan, one of the 20 amino acids commonly found in animal proteins. It has important application in the industry of plant growth. It is used to prepare indoleacetic acid (auxin) and other plant growth substances which help the development of roots in plant. It is used to make selective herbicides. Indole and its derivatives are widely used in making perfumes, agrochemicals and medicines. Methyl indole-2-carboxylic acid, is used as intermediates for the manufacture of a variety of target compounds.
SALES SPECIFICATION

APPEARANCE

 off white crystals

ACTIVE CONTENT

98.0% min

LOSS ON DRYING

0.5% max
MELTING POINT 151 - 153 C
TRANSPORTATION
PACKING

 
HAZARD CLASS  
UN NO.  
OTHER INFORMATION
European Hazard Symbols: XN, Risk Phrases: 20/21/22, Safety Phrases: 22-26-36/37/39

GENERAL DESCRIPTION OF AUXIN
Auxin is one of five (or more) major plant hormones (Auxin, Cytokinins, Gibberellins, Ethylene and Abscisic acid) which affect numerous plant growth processes functions including cell division and elongation, autumnal loss of leaves, and the formation of buds, roots, flowers, and fruit. Auxin action is inhibited by light which is an important role of the growth of stems toward light (phototropism), against the force of gravity (geotropism) and positively hydrotropic (moisture-seeking). The cells exposed to light don't grow as quickly as those on the shaded side, and thus the plant grows toward the light source. Auxins usually have a ring system with at least one double bond and attached by a side-chain that terminates in a carboxyl group. Indole acetic acid is the exact structure of Auxin activity. Parent compounds of auxin action are;
  • Auxins
    • 4-Chlorophenoxyacetic acid (CAS RN: 122-88-3)
    • (2,4-Dichlorophenoxy)acetic acid (CAS RN: 94-75-7)
    • 4-(2,4-Dichlorophenoxy)butyric acid (CAS RN: 94-82-6)
    • Tris[2-(2,4-Dichlorophenoxy)ethyl] phosphite (CAS RN: 94-84-8)
    • 2-(2,4-Dichlorophenoxy)propanoic acid (CAS RN: 120-36-5)
    • 2-(2,4,5-trichlorophenoxy)propanoic acid (CAS RN: 93-72-1)
    • Indole-3-acetic acid (CAS RN: 87-51-4)
    • Indole-3-butyric acid (CAS RN: 133-32-4)
    • 1-Naphthaleneacetamide (CAS RN: 86-86-2)
    • 1-Naphthaleneacetic acid (CAS RN: 86-87-3)
    • 1-Naphthol (CAS RN: 90-15-3)
    • Naphthoxy acetic acid (CAS RN: 120-23-0)
    • Naphthenic acid, inorganic salts (potassium, sodium)
    • (2,4,5-Trichlorophenoxy) Acetic acid (CAS RN: 93-76-5)
  • Antiauxins
    • Clofibric acid (CAS RN: 882-09-7)
    • 2,3,5-Triiodobenzoic acid (CAS RN: 88-82-4)

Cytokinin is a N6-substituted adenines acting as phytohormones  such as kinetin, zeatin, 6-isopentenyladenine, benzyl adenine. The principal functions are stimulate cell division in concert with auxin (cytokinesis) and influence the pathway of tissue differentiation (organogenesis). 6-Benzylaminopurine is the first generation synthetic cytokinin which elicits plant growth and development responses setting blossoms and stimulating fruit richness by stimulating cell division. Active cytokinin ingredients include:

  • Adenine (CAS RN: 73-24-5)
  • Adenine Hemisulfate salt (CAS RN: 321-30-2)
  • 6-Benzylaminopurine (CAS RN: 1214-39-7(base), 162714-86-5(HCl)
  • N-Benzyl-9-(2-tetrahydropyranyl)adenine (CAS RN: 2312-73-4)
  • N-(2-Chloro-4-pyridyl)-N'-phenylurea (CAS RN: 68157-60-8)
  • 6-(gamma,gamma-Dimethylallylamino)purine (CAS RN: 2365-40-4)
  • 1,3-Diphenylurea (CAS RN: 102-07-8)
  • Kinetin (CAS RN: 525-79-1 (base), 177966-68-6 (HCl)
  • 1-Phenyl-3-(1,2,3-thiadiazol-5-yl) Urea (CAS RN: 51707-55-2)
  • Zeatin (CAS RN: 13114-27-7)
  • trans-Zeatin (CAS RN: 1637-39-4 (base), 6025-81-6 (HCl))
  • trans-Zeatin riboside (CAS RN: 6025-53-2)

Other Plant Growth Regulators include:

  • Abscisic acid (CAS RN: 21293-29-8)
  • Ancymidol (CAS RN: 12771-68-5)
  • Chlorocholine chloride (CAS RN: 999-81-5)
  • Daminozide (CAS RN: 1596-84-5)
  • 3,6-Dichloro-o-anisic acid (CAS RN: 1918-00-9)
  • Gibberellic acid (CAS RN: 77-06-5)
  • Gibberellic acid Potassium salt (CAS RN: 125-67-7)
  • Gibberellin A4 (CAS RN: 468-44-0  ) and other gibberellins (more than 110 gibberellins are known)
  • Glyphosate (CAS RN: 1071-83-6)
  • Jasmonic acid (CAS RN: 3572-66-5)
  • 1,3,5-Trihydroxybenzene (CAS RN: 108-73-6)