(-)-EPIGALLOCATECHIN GALLATE

PRODUCT IDENTIFICATION

CAS NO. 989-51-5

(-)-EPIGALLOCATECHIN GALLATE 

EINECS NO.  
FORMULA

C22H18O11

MOL WT. 458.37

H.S. CODE

 

TOXICITY

 

CLASSIFICATION

 

SYNONYMS

EGCG; Tea catechin;

 (2R,3R)-2-(3,4,5-Trihydroxyphenyl)-3,4- dihydro -1(2H)- benzopyran-3,5,7- triol 3-(3,4,5- trihydroxy benzoate); 3,4-Dihydro-5,7-dihydroxy- 2R-(3,4,5- trihydroxyphenyl)-2H-1- benzopyran-3R-yl- 3,4,5- trihydroxy-benzoate;

PHYSICAL AND CHEMICAL PROPERTIES

PHYSICAL STATE white to pink powder
MELTING POINT 218 C
BOILING POINT  
SPECIFIC GRAVITY  
SOLUBILITY IN WATER Soluble
pH  
VAPOR DENSITY  

AUTOIGNITION

 

NFPA RATINGS

 

REFRACTIVE INDEX

 
FLASH POINT  
STABILITY

Stable under ordinary conditions. Hygroscopic, light sensitive.

APPLICATIONS

(-)-Epigallocatechin gallate is a polyphenolic bioflavonoid derived from a variety of plants especially green and black tea. It, chemically (2R,3R)-2-(3,4,5-Trihydroxyphenyl)- 3,4-dihydro-1 (2H)-benzopyran-3,5,7-triol 3-(3,4,5-trihydroxybenzoate), is soluble in organic solvents (e.g. ethanol, DMSO, dimethyl formamide). EGCG is a principle phenolic antioxidant to inhibit cellular oxidation of low density lipoproteins in the body. Bioflavonoids are called phytochemicals, Vitamin P, and Vitamin C2. There are about 2000 known bioflavonoids including  catechin, citrin, eriodictin, hesperetin, hesperidin, nobiletin, quercetin, rutin, sinensetin, and tangeretin. Vitamin P is not a dietary essential but is known to have the effect on capillary disorders.  It increases the strength of the walls of the blood capillaries and regulates their permeability. It may have an contribution to the total antioxidant activity and detoxifiers. It may enhance the action of Vitamin C. It is  considered that it lowers down cholesterol levels if it taken with Vitamin C. It is also know to have pharmacological action as an anti-inflammatory ,antihistaminic and antiviral agent.
SALES SPECIFICATION

APPEARANCE

white to pink powder

ASSAY

95.0 min
TRANSPORTATION
PACKING  
HAZARD CLASS not regulated
UN NO.  
OTHER INFORMATION
Hazard Symbols: XI, Risk Phrases: 36/37/38, Safety Phrases: 24/25/28A/37/45

GENERAL DESCRIPTION OF FLAVONOID

Flavonoid is any member of a class of widely distributed biological natural products containing aromatic heterocyclic skeleton of flavan (2-Phenylbenzopyran) but no nitrogen in plants. Generally, flavonoids are biological pigments providing colours from red to blue in flowers, fruit and leaves. Besides their coloring in plants, flavonoids have important roles in the growth and development of plants; protection against UV-B radiation; forming antifungal barriers; antimicrobial, insecticidal and oestrogenic activities; plant reproduction. Flavonoids also exhibit a wide range of biological properties including anti-microbial, insecticidal and oestrogenic activities. Flavonoids are usually classified into main 6 subgroups as below plus flavans, neoflavonoids, flavonols, aurons, catechins according to the structural patterns.
  • Flavonols (Hydroxy derivatives of flavone): Fisetin, Galangin, Kaempferide, Kaempferol, Morin, Myricetin, Myricitrin, Quercetin, Quercetrin, Rhamnetin, Robinin, Rutin, Spirenoside
  • Flavones (skeleton: 2-phenylchromen-4-one): Apigenin, Baicalein, Chrysin, Diosmetin, Diosmin, Flavone, Luteolin, Rpoifolin,Tangeretin, Techtochrysin, Rhamnazin, Nobiletin, Natsudaidain.
  • Isoflavones (skeleton: 3-phenylchromen-4-one): Daidzin, Genistein, Irilone, Luteone, Prunetin, Pratensein,
  • Flavonones (derivation by reduction of the 2(3) C=C bond): Eriodictyol, Hesperidin, Hesperetin, Likvirtin, Naringin; Naringenin; Pinocembrin
  • Flavanols (derivation by reduction of the keto group):(+)-Catechin, (+)-Gallocatechin, (-)-Epicatechin (EC), (-)-Epigallocatechin (EGC), (-)-Epicatechin 3-gallate (ECG), (-)-Epigallocatechin 3-gallate (EGCG), Theaflavin, Theaflavin 3-gallate, Theaflavin 3'-gallate, Theaflavin 3,3' digallate, Thearubigins
  • Anthocyanidins (aglycones of the glycoside anthocyanins): Apigeninidin, Cyanidin, Delphinidin, Diosmetinidin, Guibourtinidin, Fisetinidin, Luteolinidin, Malvidin, Pelargonidin, Peonidin, Robinetinidin, Tricetinidin, Capensinidin, Petunidin, Europinidin, Aurentinidin, Columnidin, 5-Desoxy-malvidin, 5-Desoxy-peonidin, Hirsutinidin, Rosinidin

PRICE INFORMATION