PRODUCT IDENTIFICATION
206-327-7
H.S. CODE
TOXICITY
Oral Rat intraperitoneal LD50: 6429mg/kg
CLASSIFICATION
Proteinogenic amino acid, Ketogenic amino acid, Essential amino acid
EXTRA NOTES
PHYSICAL AND CHEMICAL PROPERTIES
white crystals
AUTOIGNITION
NFPA RATINGS
REFRACTIVE INDEX
Stable under ordinary conditions. Moisture, light sensitive.
EXTERNAL LINKS & GENERAL DESCRIPTION
http://www.exrx.net/
The essential branched chain amino acids (BCAA's) include leucine, isoleucine,
and valine are of special importance for athletes because they are metabolized
in the muscle, rather than in the liver. Theoretically, after digestion
once protein is broken down into individual amino acids these amino acids can
either be used to build new proteins or be burned as fuel to produce energy. If
the athlete's diet is adequate in nutrition then the above "essential" amino
acids will be used for protein synthesis which is optimal for advanced human
performance. It should also be noted that essential amino acids are not produced
in the body such as non-essential amino acids, but rather obtained through
proper nutrition. Therefore, it is often theorized that the supplementation of
BCAA's are of essential importance to athletes due to their ability to alleviate
any deficiencies that the body alone cannot produce. BCAA's have also been known
in reducing fatigue in both anaerobic and endurance sports. It has also been
noted that leucine may be the most critical BCAA because of its anti-catabolic
properties and vital role in protein synthesis
http://www.webmd.com/
Branched-chain amino acids stimulate the building of protein in muscle and
possibly reduce muscle breakdown. Branched-chain amino acids seem to prevent
faulty message transmission in the brain cells of people with advanced liver
disease, mania, tardive dyskinesia, and anorexia.
Local:
Valine, Isoleucine and Leucine are all branched-chain amino acids which can be
burned for fuel in the cells to promotes muscle recovery when in balance with
each other most effective. Only the L-stereoisomers appear in mammalian protein.
They play a role in wound healing and the growth of new tissue. These branched
amino-acids are needed to increase the bio-availability of complex carbohydrate
intake and are absorbed by the muscle cells for anabolic muscle building
activity. Branched amino-acids (Valine, Isoleucine and Leucine ) with tryptophan
and phenylalanine (aromatic side chain amino acids) contribute to the structure
of protein by the tendency of its side chain composed only of carbon and
hydrogen to participate in hydrophobic interactions which determines the
tertiary structure of the peptide chain. Isoleucine, chemically
2-amino-3-methylvaleric acid, is a monocarboxylic amino acid occurring in most
dietary proteins. It is necessary for optimal growth in infants and for nitrogen
equilibrium in human adults. Leucine, chemically 2-amino-4-methylvaleric acid,
is the isomer of isoleucine. Their methyl branch positions are difference,
which show different properties of them. Norleucine, chemically
2-aminohexanoic acid, is the unbranched isomer. The prefix nor- describes
normal structure which has no branched chain of carbon atoms. (In case of
norepinephrine, it has one less methylene group than its homologue, epinephrine). Norleucine is a nonessential amino acid extracted from the
leucine fraction of the decomposition of the proteins of nervous tissue.
Commercial norleucine is synthesized for peptidomimetics to prepare unnatural
and unusual amino acids and amino acid analogs as well as to modify peptides.
APPEARANCE
white crystals
98.5 - 101.0%
SPECIFIC ROTATION
-14° ~ -16° (C=5 in 5N HCl)
LOSS ON DRYING
0.2% max
RESIDUE ON IGNITION
0.1% max
CHLORIDE
0.02% max
SULFATE
0.03% max
HEAVY METALS
10ppm max
IRON
10ppm max
ARSENIC
1ppm max
AMMONIUM SALTS
0.02% max
PRICE INFORMATION