| CAS
NO. |
50-70-4 |
|
| EINECS NO. |
200-061-5 |
| FORMULA |
C6H14O6 |
| MOL
WT. |
182.17 |
|
H.S.
CODE
|
2905.44 |
|
TOXICITY
|
Oral rat LD50: 15900 mg/kg |
| SYNONYMS |
Glucitol;
Cholaxine; D-Glucitol; D-Sorbite; |
| Hexahydric Alcohol;
Karion; L-Gulitol; Nivitin; Sionit; Sorbostyl;
Sorvilande; |
| SMILES |
hydrogenation of glucose sugar
|
|
CLASSIFICATION
|
|
|
PHYSICAL AND CHEMICAL PROPERTIES
(70%)
|
| PHYSICAL
STATE |
clear to
light yellow syrupy
liquid |
| MELTING POINT |
93 to 98
C
|
| BOILING
POINT |
295
C |
| SPECIFIC GRAVITY |
1.28 |
| SOLUBILITY
IN WATER |
Freely soluble
(soluble
in acetic acid, methanol and ethanol) |
|
SOLVENT
SOLUBILITY
|
insoluble in common
organic solvents |
| pH |
ca
7 (10% Sol.) |
| VAPOR DENSITY |
|
|
AUTOIGNITION
|
|
|
NFPA
RATINGS
|
Health: 0 Flammability: 1 Reactivity: 0 |
|
REFRACTIVE
INDEX
|
1.4600 |
| FLASH
POINT |
|
| STABILITY |
Stable
under ordinary conditions |
|
GENERAL
DESCRIPTION & APPLICATIONS
|
|
Sorbitol is a white, sweetish, hygroscopic, crystalline sugar alcohol of
six-carbon. It is found naturally in various berries and fruits. Or it is
prepared synthetically by high-pressure catalytic hydrogenation of glucose sugar
derived from cornstarch. It melts at 93 to 98 C depending on the form. It is
used as a a sweetening agent, food additive, toothpaste, tobacco, toiletries and
in cosmetics. It is used for vitamin-C fermentation. It is used as a excipient
and intravenous osmotic diuretic in pharmaceutical fields. It is also used in
the manufacture of polyethers for polyurethanes and surfactants. |
| SALES
SPECIFICATION (70%
SOLUTION) |
|
APPEARANCE
|
clear to
light yellow syrupy
liquid |
|
SOLID
CONTENT
|
70.0%
min
|
|
REDUCING
SUGAR |
0.5%
max |
|
pH |
5
- 7 |
|
CHLORIDES
|
0.005%
max
|
|
SULFATES
|
0.01%
max
|
|
ASH
|
0.1%
max
|
|
ARSENIC
|
2ppm
max
|
|
HEAVY
METALS
|
5ppm
max
|
|
NICKEL |
5ppm
max |
|
IRON |
10ppm
max |
| TRANSPORTATION |
| PACKING |
250kgs
in drum |
| HAZARD CLASS |
Not regulated |
| UN
NO. |
|
| OTHER
INFORMATION |
|
Hazard
Symbols: n/a, Risk Phrases:n/a Safety Phrases: 24/25 |
|
GENERAL
DESCRIPTION OF EXCIPIENT
|
|
Excipients are added to ensure that the shelf-life of the active ingredients can
be long enough to be active until internal use. Excipients are combined also to
support the active ingredients, so that the latter can be easily administered or
absorbed in the body.
EXAMPLES OF
EXCIPIENT
| Excipient |
CAS
RN
|
| Acacia
gum |
9000-01-5 |
| Calcium sulfate |
7778-18-9 |
| Carboxymethylcellulose
Sodium |
9004-32-4 |
| Carrageenan
gum |
9000-07-1 |
| Crospovidone |
9003-39-8 |
| 1-Deoxy-1-(octylamino)-D-glucitol |
23323-37-7 |
| Dimethyl sulfoxide |
67-68-5 |
| Dioctyl sulfosuccinic acid
and its salts |
|
| Fosveset |
193901-91-6 |
| Gelatin |
9000-70-8 |
| Hydroxypropyl
methylcellulose |
9004-65-3 |
| Karaya gum |
9000-36-6 |
| Laurocapram |
59227-89-3 |
| Meglumine |
6284-40-8 |
| Nonoxynol
|
26027-38-3 |
| N-Stearoylglycine
|
158305-64-7 |
| Octabenzone |
1843-05-6 |
| Octoxynol |
9002-93-1 |
| Phthaloyl chloride |
88-95-9 |
| Polipropene |
9003-07-0 |
| Poloxamer |
106392-12-5 |
| Polyethylene glycol ethers |
25322-68-3 |
| Propyleneglycol
esters |
|
| Sorbitol
|
50-70-4 |
| Sucrose |
57-50-1 |
| Talc |
14807-96-6 |
| Taurodeoxycholic acid
|
516-50-7 |
| Tragacanth
|
9000-65-1 |
| Tricaprilin |
538-23-8 |
| Tromethamine |
77-86-1 |
|