| CAS
NO. |
90-05-1 |
|
| EINECS NO. |
201-964-7
|
| FORMULA |
C7H8O2 |
| MOL
WT. |
124.14 |
|
H.S.
CODE
|
|
|
TOXICITY
|
|
| SYNONYMS |
Pyrocatechol monomethyl ether;
Pyroguaiac acid; |
| 1-hydroxy-2-methoxybenzene; o-Hydroxyanisole;
2-Methoxyphenol; o-Methylcatechol; Catechol monomethyl ether; Guaicol;
Methyl Catechol;
Hydroxy-2-methoxybenzene; |
| SMILES |
|
|
CLASSIFICATION
|
|
|
GENERAL DESCRIPTION OF DIHYDROXYBENZENE |
|
There are three
isomeric compounds of dihydroxybenzene molecule structure, which all have
traditional names respectively. The ortho (1,2) isomer is called catechol (Also
known as catechin; pyrocatechol; pyrocatechuic acid), which forms clear crystals
used as a photographic developer in solution and as a starting material to
produce synthetic catecholamines which have important physiological effects as
neurotransmitters and hormonesany (such as epinephrine, adrenaline,
norepinephrine, and dopamine). The meta (1,3) isomer is resorcinol (also known
as resorcin), which forms clear needle crystals used in the production of diazo
dyes and plasticizers. It is produced by sulfonating benzene with fuming
sulfuric acid and fusing the resulting benzenedisulfonic acid with caustic soda.
Resorcinol is used in resins as an UV absorber. It is used in manufacturing
fluorescent and leather dyes and adhesives. Reaction with formaldehyde produces
resins (resorcinol formaldehyde resins) used to make rayon and nylon. It is used
as a pharmaceutical to treat acne and other greasy skin conditions in
combination with other acne treatments such as sulfur. It is used as an
anti-dandruff agent in shampoo and sunscreen cosmetics. It is also used as a
chemical intermediate to synthesis pharmaceuticals and other organic compounds.
The para (1,4) isomer is hydroquinone (also known as quinol), which forms clear
prisms used as a photographic reducer and developer (except in color film). It
is formed in large quantities by chemical reduction of benzoquinone. This
compound is a general-purpose inhibitor, stabilizer, antioxidant, and
intermediate. One of the major uses of hydroquinone is as an intermediate to make
other inhibitors, stabilizers, antioxidants, agricultural chemicals, and dyes.
Resorcinol and its derivatives are used in resins as UV absorbers. They are used
in manufacturing fluorescent and leather dyes and adhesives (resorcinol
formaldehyde resins). They are used as pharmaceuticals to treat acne and other
greasy skin conditions in combination with other acne treatments such as sulfur.
They are used as an anti-dandruff agent in shampoo and sunscreen cosmetics.
|
|
PHYSICAL AND CHEMICAL PROPERTIES
|
| PHYSICAL
STATE |
amber crystals |
| MELTING POINT |
28 - 32 C |
| BOILING
POINT |
204
- 206 C |
| SPECIFIC GRAVITY |
1.12 |
| SOLUBILITY
IN WATER |
Slightly soluble |
| pH |
|
| VAPOR DENSITY |
4.3 |
|
AUTOIGNITION
|
385 C |
|
NFPA
RATINGS
|
Health: 2 Flammability: 2 Reactivity: 0 |
|
REFRACTIVE
INDEX
|
1.5430 |
| FLASH
POINT |
82
C
|
| STABILITY |
Stable
under ordinary conditions. Light,
air sensitive. |
|
APPLICATIONS
|
|
Guaiacol is the methyl ether of pyrocatechol. It is a main constituent of
creosote obtained from wood tar (mainly beech) by distillation mostly between
203 and 220 C. It is synthesized from anisole also. The dimethyl ether of pyrocatechol is called veratrol. They and
their derivatives are used as an external antiseptic, expectorant, gastric
sedative, deodorant, and as a parasiticide. Methoxyphenols
are used in manufacturing stabilizers and antioxidants for plastics and rubbers.
They are also used in analgesics, local anesthetic,
flavorings, biocides, antiseptics. 2-Methoxyphenol is
used in manufacturing vanillin and other flavorings.
|
| SALES
SPECIFICATION |
|
APPEARANCE
|
off-white crystals |
|
ASSAY |
97.0%
min |
|
MOISTURE |
0.2% max |
| TRANSPORTATION |
| PACKING |
200kgs
in drum |
| HAZARD CLASS |
Not
regulated |
| UN
NO. |
|
| OTHER
INFORMATION |
|
Hazard
Symbols: XN, Risk Phrases: 22-36/38,
Safety Phrases: 26 |
|
MEMBERS
OF EXPECTORANT
|
|
Expectorant
|
CAS
RN
|
| 10-Camphorsulfonic acid |
5872-08-2 |
| 4-Carbomethoxythiazoline
|
60667-24-5 |
| 9-Hydroxy-19,20-bisnorprostanoic
acid |
82598-17-2 |
| 4-Amino-3-bromo-5-((diethylamino)methyl)benzoic acid
ethyl ester HCl |
57814-29-6 |
| Acetylcysteine |
616-91-1 |
| Actifed |
8054-27-1 |
| Adamexina
|
76270-03-6 |
|
|
|
| Ambroxol |
18683-91-5 |
|
|
1066-33-7 |
|
Ammonium
carbamate |
1111-78-0 |
|
Ammonium |
506-87-6 |
|
Ammonium chloride
|
12125-02-9 |
|
|
28300-74-5 |
| Anthorhododendrin
|
53127-04-1 |
| Antimony potassium tartrate |
|
| Asada-ame
|
124399-50-4 |
|
8050-35-9 |
| Bromhexine
|
3572-43-8 |
| Bromhexine hydrochloride |
611-75-6 |
| Brovanexine |
54340-61-3 |
| Carbocysteine |
2387-59-9 |
| Chymaphylline |
76095-52-8 |
| Citiolone |
1195-16-0 |
|
8021-39-4 |
| Dithiothreitol |
3483-12-3 |
| Domiodol |
61869-07-6 |
| Eprazinone
dihydrochloride |
10402-53-6 |
|
Erdosteine
|
84611-23-4 |
|
470-82-6 |
|
|
8000-48-4 |
| Farrerol |
24211-30-1 |
| Fudosteine |
13189-98-5 |
| Iodopropylidene glycerol |
5634-39-9 |
|
Glycyrrhiza |
|
| Guacetisal |
55482-89-8 |
| Guaiacol |
90-05-1 |
|
Guaiacolsulfonic acid |
50855-43-1 |
| Guaifenesin |
93-14-1 |
| Guaimesal |
81674-79-5 |
| Guaithylline |
5634-38-8 |
| Mucantil |
64585-60-0 |
| Ipecac |
8012-96-2 |
| N-Amidinocysteine |
40454-21-5 |
| Letosteine |
53943-88-7 |
| Linctifed |
77944-85-5 |
| Luteolin |
491-70-3 |
| Matteucinol |
489-38-3 |
| Mecysteine |
2485-62-3 |
| 2-Mercaptoethanesulfonic acid sodium salt |
19767-45-4 |
| Nevadensin
|
10176-66-6 |
| Ningpeisinoside
|
139742-29-3 |
| Orange oil
|
8008-57-9 |
| Ozothine
|
8031-65-0 |
| Potassium |
78247-49-1 |
| Potassium Citrate |
6100-05-6 |
| Potassium iodide |
7681-11-0 |
| Prorenoate potassium |
49847-97-4 |
| S-Ethylcysteine
|
2139-90-4 |
| Sobrerol |
498-71-5 |
|
|
7681-82-5 |
| Sodium acetate |
6131-90-4 |
| Solutan |
81064-46-2 |
| Spironolactone |
52-01-7 |
| Stepronin |
72324-18-6 |
| Sulfogaiacol |
1321-14-8 |
| Terpin anhydrous
|
80-53-5 |
| Terpin hydrate
|
2451-01-6 |
| Thiophene-2-carboxylate
|
527-72-0 |
|
|
8007-46-3 |
|